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All Journal Buletin Peternakan Jurnal Sains dan Teknologi Peternakan Warta Perkaretan Journal of Biobased Chemicals (JOBC) Sewagati
Rahmawati, Atiqa
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Engineering Materials Science & Nanotechnology Social Sciences Veterinary Other

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Journal : Journal of Biobased Chemicals (JOBC)

 1 
Comparison of Pegagan (Centella asiatica (L.)) Extraction with Ultrasound-Assisted Extraction and Microwave-Assisted Extraction Methods Using Response Surface Methodology Rahmawati, Ayu Ulum; Rahmawati, Atiqa
Journal of Biobased Chemicals Vol. 2 No. 1 (2022): Journal of Biobased Chemicals
Publisher : Program Studi Teknik Kimia Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (590.032 KB) | DOI: 10.19184/jobc.v2i1.117

Abstract

Pegagan (Centella asiatica (L.)) is one of the herbaceous plants that grow, and flowers throughout the year. Pegagan has been used for hundreds of years, especially in the dermatology, and cosmetology industries. Pegagan (Centella asiatica (L.)) has distinctive bioactive components, namely triterpene ester glycoside compounds in the form of asiaticoside, and madecoside as well as triterpene group compounds in the form of asiatic acid, and madecasic acid. There are various extraction methods to produce the following compounds namely, conventional extraction methods, and modern extraction methods. The two methods have differences in the results obtained. Therefore, the difference in the extraction method will determine the result of the difference in the levels of a compound. So that this research was carried out on the effect of Pegagan (Centella asiatica (L.)) extraction using a comparison of the Microwave-Assisted Extraction (MAE), and Ultrasound-Assisted Extraction (UAE) methods on the total phenol content in the Pegagan (Centella asiatica (L.)) extracted. Analysis of the extracteded bioactive content was carried out by analyzing the total phenol content using the Folin-Ciocalteau reagent method and analyzing the data through the Analysis of Response Surface Design expert 11 to see the significance of the research variables. The results obtained from the study are in the form of a comparison of the optimal conditions for the total phenol content, namely, the comparison between the UAE, and MAE methods for Centella asiatica (L.). extracted with ethanol solvent which is more optimal by using the MAE method because in a short time it can produce 1130.7882 mg.
Optimization of Extraction of Bioactive Compound from Pegagan Leaves Using Ethanol Solvent With Microwave-Assisted Extraction Method (MAE) Rohmah, Fira Ulvatur; Rahmawati, Atiqa; Rizkiana, Meta Fitri; Susanti, Ari
Journal of Biobased Chemicals Vol. 2 No. 1 (2022): Journal of Biobased Chemicals
Publisher : Program Studi Teknik Kimia Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (514.436 KB) | DOI: 10.19184/jobc.v2i1.119

Abstract

Treatment using natural ingredients in Indonesia is the main choice that is growing in society. This is because treatment with natural ingredients has relatively milder side effects compared to synthetic treatment. Therefore, further research is needed on natural ingredients that can be used as natural medicines, one of which is pegagan (Centella asiatica (L.)). Several studies have found bioactive compounds in pegagan that can be used as medicine by various methods. The author wants to know the optimal conditions for extracting pegagan bioactive compounds using the microwave-assisted extraction (MAE) method. This study used pegagan leaf size 40 mesh that had been dried. pegagan leaves were extracted using ethanol as a solvent with microwave power, solvent concentration, and extraction time as variables. Variable power 150 watts, 300 watts, and 450 watts. Variable solvent concentration 25%, 50%, and 75%. Variable extraction time for 5, 10, and 15 minutes. Analysis of the results of the study was carried out using total phenol analysis using the Folin-Ciocalten method. The research data obtained optimum operating conditions at 75% solvent concentration, 450-watt microwave power, and extraction time of 10 minutes with a total phenol content of 1251.410225 mg AGE/g sample.
Co-Authors Abdullah, Sofwan Siddiq Adamu, Dahiru J M Adetya, Nais Pinta Agustian, Mertza Fitra Ajie, Baskoro Andri Saputra Ari Susanti Asfan, Muhammad Dwi Wulandari Heru Budi Susanto, Heru Budi Jonathan, Sebastian Lubis, Dina Mariana Uli Maryati, Tutik Meta Fitri Rizkiana Mizan, Al Nurwantoro Putri, Naimah R. Lukas Martindro Satrio Ari Wibowo, R. Lukas Martindro Satrio Ari Rahmawati, Ayu Ulum Robbika, Fadzkurisma Rohmah, Fira Ulvatur Tarigan, Deo Steven Barney Ukhdiyati, Mustafidah Uma Fadzilia Arifin, Uma Fadzilia Wibowo, Raden Lukas Martindro Satrio Ari Yuliatmo, Ragil