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All Journal HAYATI Journal of Biosciences JURNAL PENDIDIKAN TAMBUSAI International Journal of Applied Mathematics, Sciences, and Technology for National Defense Jurnal Pengabdian Sosial
Azzahra, Salsabila
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Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Law, Crime, Criminology & Criminal Justice Mathematics Physics Public Health Social Sciences

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Specific function of vitamin D in bone Ramadhani, Dennisa Putri; AD, Hammanda; Azzahra, Salsabila; Rizkyadsyah, Akbar; Ulayya, Anis; Fendiyanto, Miftahul Huda
International Journal of Applied Mathematics, Sciences, and Technology for National Defense Vol 2, No 2 (2024): International Journal of Applied Mathematics, Sciences, and Technology for Natio
Publisher : FOUNDAE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58524/app.sci.def.v2i2.347

Abstract

There are two sources of vitamin D, namely from food and sun exposure. The content of vitamin D is given beneficial in bone and mineral metabolism. Vitamin D helps absorption of calcium in the intestines, thereby accelerating bone mineralization. Bone metabolism is a complex process that occurs throughout life. Very high doses of vitamin D can stimulate an increased rate of bone loss. Vitamin D deficiency causes bone demineralization. Which can cause a decrease in calcium absorption. The functions of these metabolites vary widely in vital metabolic pathways. This review aims to determine the specific function of vitamin D in bone. The search for the data base was carried out by the analytical method.  Vitamin D which is absorbed from food or comes from the skin turns into an active form in the form of 1,25- (OH) 2-D3 which will enter the bloodstream, playing an important role in bone and extra-skeletal health.
Analisis Pengaruh Strategi Promosi Word of Mouth pada Bisnis Kecil dan Menengah Pancong Lumer 88 Nabiilah, Rifdah; Azzahra, Salsabila; Junita, Sielve Dwi; Noviyanti, Indah
Jurnal Pendidikan Tambusai Vol. 8 No. 2 (2024)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

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Abstract

Pancong Lumer 88 merupakan usaha kecil dan menengah yang bergerak dibidang kuliner yang menjual kue Pancong dengan berbagai macam rasa dan topping dengan harga yang terjangkau. Penelitian ini bertujuan untuk memahami dampak dari strategi promosi word of mouth (WOM) terhadap Usaha Pancong Lumer 88. Penelitian ini berupa artikel berdasarkan sumber deskriptif dan kualitatif menggunakan data primer dan data sekunder. Untuk memperoleh informasi yang lebih detail dan akurat tanpa menggunakan kuesioner, Peneliti melakukan wawancara langsung dengan pihak Pancong Lumer 88. Hasil dari penelitian ini membuktikan bahwa straregi promosi Word Of Mouth (WOM) memiliki dampak yang signifikan terhadap keputusan pembelian Pancong Lumer 88.
Naringin Effect on SARS-CoV-2 Pseudovirus Entry and Spike Mediated Syncytia Formation in hACE2-overexpressing Cells Septisetyani, Endah Puji; Prasetyaningrum, Pekik Wiji; Paramitasari, Komang Alit; Suyoko, Ahmad; Himawan, Alayna Lillahida Indri; Azzahra, Salsabila; Wisnuwardhani, Popi Hadi; Anam, Khairul; Ramadani, Ratna Dwi; Santoso, Adi; Ningrum, Ratih Asmana; Herawati, Neng; Rubiyana, Yana
HAYATI Journal of Biosciences Vol. 31 No. 2 (2024): March 2024
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.31.2.336-347

Abstract

A molecular docking study demonstrates the interaction between naringin, a citrus flavonoid, with SARS-CoV-2 spike RBD. Nevertheless, in vitro investigation of the inhibitory effect of naringin on SARS-CoV-2 entry and syncytia models has yet to be carried out. We synthesized VSV∆G-GFP/Spike* pseudovirus (PSV) as a SARS-CoV-2 model by pseudotyping VSV∆G-GFP/S* in BHK-21 cells overexpressing the SARS-CoV-2 spike glycoprotein. In the SARS-CoV-2 PSV entry assay, we utilized CHO-K1 cells transfected with hACE2 plasmid, which were then treated with naringin and SARS-CoV-2 PSV/naringin. After 16-18 h incubation, PSV internalization represented by the GFP signal was observed under a fluorescence microscope. Immunofluorescence staining was also performed to probe the SARS-CoV-2 spike and confirm the PSV entry. We performed a syncytia assay using 293T cells co-transfected with SARS-CoV-2 spike/hACE2. Six hours after transfection, the cells were treated with naringin and incubated for another 16-18 hours. Then, we observed syncytia using a phase contrast microscope. Based on fluorescence foci quantification, the results indicated that naringin might inhibit SARS-CoV-2 PSV entry at a concentration of 100 µM (P<0.05). However, naringin did not prevent syncytia formation compared to solvent control. These PSV entry and syncytia assay results suggested that naringin potentially inhibited SARS-CoV-2 viral infection but not cell-to-cell viral transmission.
Peningkatan Pengetahuan Masyarakat Dalam Mengungkap Potensi Desa Barusari Kabupaten Garut Di Bidang Pertanian Melalui Citizen Journalism Payu, Satria Muhammad Jahsy; Ridwan, Zalfa Adira; Siddiqa, Kamila; Nurhakim, Ridwan; Mulyani, Syifa Salsabila; Azzahra, Salsabila; Sumarna, Cahya; Azizah, Siti Nur; Sholihati, Rena; Widiarti, Intan; Fauzi, Muhammad
Jurnal Pengabdian Sosial Vol. 1 No. 11 (2024): September
Publisher : PT. Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/7071gh30

Abstract

Kemudahan masyarakat dalam mengakses internet belum dibarengi dengan kemampuan memanfaatkannya secara konstruktif. Program jurnalisme warga dapat menjadi salah satu cara pemanfaatan internet, khususnya melalui media sosial, untuk menstimulasi potensi desa. Keberadaan Internet telah memicu minat baru terhadap jurnalisme warga. Workshop Jurnalisme Warga Desa Barusari bertujuan untuk meningkatkan kapasitas masyarakat dalam mengeluarkan potensi lokal khususnya di sektor pertanian dan UMKM melalui pemberdayaan jurnalisme warga. Metode yang digunakan kuantitatif dengan memberikan edukasi dan pelatihan citizen journalism kepada masyarakat Desa Barusari melalui metode pembelajaran konvensional, diskusi, kemudian praktek setelah pemberian materi dan diskusi selesai dilakukan. Narasumber pelatihan Jurnalistik yaitu dari media Garut intan news dan Dinas pertanian. Hasil yang didapat ditunjukan untuk mengedukasi kepada masyarakat terkait pentingnya citizen journalism bagi desa agar dapat meningkatkan potensi yang ada di desa Barusari. Berdasarkan pada grafik.1 yang dihasilkan bahwa kegiatan program pelatihan ini sangat bermanfaat dan dapat membantu masyarakat khususnya warga Desa Barusari dalam peningkatan pengetahuan dalam mengungkap potensi desa di bidang pertanian melalui Citizen Journalism. Kesimpulan yang didapat untuk meningkatkan pengetahuan masyarakat tentang pentingnya citizen journalism dalam mengungkap potensi desa, khususnya di bidang pertanian.
Co-Authors AD, Hammanda Anam, M. Khairul Endah Puji Septisetyani, Endah Puji Fendiyanto, Miftahul Huda Himawan, Alayna Lillahida Indri Intan Widiarti Junita, Sielve Dwi Komang Alit Paramitasari Muhammad Fauzi Mulyani, Syifa Salsabila Nabiilah, Rifdah Neng Herawati, Neng Noviyanti, Indah Nurhakim, Ridwan Payu, Satria Muhammad Jahsy Popi Hadi Wisnuwardhani, Popi Hadi Prasetyaningrum, Pekik Wiji Ramadani, Ratna Dwi Ramadhani, Dennisa Putri RATIH ASMANA NINGRUM Ridwan, Zalfa Adira Rizkyadsyah, Akbar Santoso, Adi Sholihati, Rena Siddiqa, Kamila Siti Nur Azizah, Siti Nur Sumarna, Cahya Suyoko, Ahmad Ulayya, Anis Yana Rubiyana, Yana