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All Journal International Journal of Nasopharyngeal Carcinoma
Afriani Dewi, Yussy
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Health Professions Medicine & Pharmacology

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CHARACTERISTICS OF RECURRENCE NASOPHARYNGEAL CARCINOMA IN HASAN SADIKIN HOSPITAL PERIOD 2017-2019 Adithya Prawiranata, Mohammad; Afriani Dewi, Yussy
INTERNATIONAL JOURNAL OF NASOPHARYNGEAL CARCINOMA Vol. 2 No. 02 (2020): International Journal of Nasopharyngeal Carcinoma
Publisher : TALENTA PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijnpc.v2i02.3843

Abstract

Abstract Introduction: Nasopharyngeal carcinoma is a malignancy that occurs in the squamous epithelium in the nasopharynx region. Recurrent Nasopharyngeal carcinoma is defined as tumor recurrence after the complete remission. Patients with recurrent NPC always experience local, regional, or both failure, with or without distant metastases and can damage surrounding tissue.. Methods: This research method was a retrospective descriptive based on medical record data in patients with recurrent nasopharyngeal carcinoma at ORL-HNS outpatient ward subdivision of Head Neck Surgery, RSHS, Bandung from 2017 to 2019. Result: In RSHS Bandung, there was 1727 patient NPC period 2017-2019. There was 135 recurrent nasopharyngeal carcinoma patients (7,8 %) consist of 96 male and 39 female, aged over 40 years as many as 107 patients. More patients were found in T3-T4 (56%), N2-N3(56%), M0 (91%), stage III-IV (75%). The duration of the patient experienced a relapse after initial therapy for more than 24 months (52%).  Conclusion: Characteristics of recurrent nasopharyngeal carcinoma most of them come with stage III-IV, T3-T4 without distant metastases, with a recurrence within less than 24 months. There was 7,8% recurrent nasopharyngeal carcinoma patients Keywords: Charactherisic, Nasopharyngeal Carcinoma, Recurrence
EFFECT OF SEA CUCUMBER OIL AND HONEY IN POST RADIOTHERAPY NASOPHARYNGEAL CARCINOMA PATIENTS Hendrawan, Wawan; Soeseno, Bogi; Basriyadi S, Tonny; Afriani Dewi, Yussy; Burhanuddin, Ade
INTERNATIONAL JOURNAL OF NASOPHARYNGEAL CARCINOMA Vol. 2 No. 02 (2020): International Journal of Nasopharyngeal Carcinoma
Publisher : TALENTA PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijnpc.v2i02.3899

Abstract

Abstract Introduction: Nasopharyngeal carcinoma is one of the most commonly found cases of head and neck malignancy. The most common side effects of radiotherapy is skin damaged. Until now, there is no standard therapy that has been given to post radiotherapy patient in Hasan Sadikin Hospital. Sea cucumber and honey can accelerate the healing process of the wound caused by radiotherapy. Objective: This study was conducted to compare the effects of the use topical sea cucumber oil and honey in patient with nasopharyngeal carcinoma post radiotherapy. Method: The study was conducted at Radiotherapy Clinic in Hasan Sadikin Hospital from may until September 2015 with patients who experienced skin damaged level two or more based on the criteria of Radiation Therapy Oncology Group (RTOG). This was an experimental study. Subjects were selected consecutively between the two groups: sea cucumber oil group and honey group. The draft analysis was done using Randomized Controlled Trial (RCT). Result: 30 patients were divided equally into two groups, sea cucumber group and honey group. Most of the nasopharyngeal carcinoma patients were >45 years old, the ratio man to woman was 2-3:1, with the BMI was <18.5. All subjects in this study experienced recovery rate up to level 1 (p=1.0), after one week of treatment. In the 2nd week after treatment all patients in the sea cucumber group achieved recovery up to level 0, and in the honey group as much as 2 patients only experienced the recovery rate to level 0, while the remaining 13 subjects remained at level 1 (p=0.0001). It was found that the wound healing process occurs better in sea cucumber oil group than the honey group (p=0.0001). Conclusion: Sea cucumber oil accelerates the healing process of the skin tissue damaged in patients with nasopharyngeal carcinoma after radiotherapy, faster than with honey.
Co-Authors Adithya Prawiranata, Mohammad Basriyadi S, Tonny Bogi Soeseno Burhanuddin, Ade Desyandri Desyandri