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All Journal Jurnal MIPA PHARMACON
Mansauda, Karlah Lifie Riani
Universitas Sam Ratulangi
Biochemistry, Genetics & Molecular Biology Chemistry Mathematics Medicine & Pharmacology Physics

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Neomycin Sulfate Emulgel Formulation With Avocado Seed Starch As Gelling Agent Vinny Valentina Kaitu; Hosea Edy; Karlah Lifie Riani Mansauda
PHARMACON Vol. 12 No. 1 (2023): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.12.2023.42938

Abstract

Emulgel is a combined form of emulsion and gel dosage that is stable with the addition of a gelling agent. Starch can also be used as an additive in gel dosage as a gelling agent. This study aims to formulate a modification of acetylation of avocado seed starch as a gelling agent for neomycin sulfate emulgel preparations. Avocado seed starch was modified by the acetylation method. The emulgel formula was made with a concentration of avocado seed starch gelling agent of 2%, 4%, 6%, and 8%. The physical evaluation of neomycin sulfate emulgel preparations included organoleptic tests, homogeneity tests, pH tests, adhesion tests, and dispersion tests. The results showed that acetylated modified avocado seed starch can be used as a gelling agent in emulgel preparations and that all neomycin sulfate emulgel preparation formulas met the requirements for physical evaluation of the preparation.
Co-Authors Adithya Yudistira ERLADYS MELINDAH RUMONDOR, ERLADYS MELINDAH Hosea Edy Jayanto, Imam Kumakauw, Vanesa Vebiola Langi, Priski Mokoginta, Rizkah V. Rante, Trian Rizki Kala’ Ryan Irwanto Tunggal Simbala, Herny E. I. Simbala, Herny Emma Inonta Sumerah, Marsella Sumerah, Marsella E. Surya Sumantri Abdullah Tunggal, Ryan Irwanto Vinny Valentina Kaitu