Laqif, Abdurahman
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EFFECT ON AUTO TRANSPLANTION TO ESTRADIOL LEVEL OF EARLY MENOPAUSE WISTAR RATS Laqif, Abdurahman; Mushthafa, Mufti; Budhiastuti, Uki Retno
Jurnal Ilmu Keperawatan dan Kebidanan Vol 11, No 1 (2020): JURNAL ILMU KEPERAWATAN DAN KEBIDANAN
Publisher : STIKES Muhammadiyah Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26751/jikk.v11i1.734

Abstract

Latar Belakang : Modalitas pengobatan utama untuk tumor ganas adalah operasi, kemoterapi dan / atau radioterapi yang bersifat gonadotoksik. Terapi kanker dapat mempengaruhi fungsi ovarium, baik produksi hormon dan potensi reproduksi. Konsekuensi terburuk adalah insufisiensi ovarium prematur dan infertilitas. Salah satu  cara mempertahankan fungsi reproduksi berupa simpan beku dan auto transplantasi ovarium. Metode: Penelitian eksperimental analitik ini dilakukan pada 27 tikus Wistar (Rattus novergicus) yang dibagi menjadi 3 kelompok. Kelompok 1 (K1) tidak dilakukan bilateral ooforektomi. Kelompok 2 (K2) dilakukan bilateral ooforektomi tanpa auto transplantasi. Kelompok 3 (K3) dilakukan bilateral ooforektomi dengan auto transplantasi. Pengambilan sampel dilakukan pada hari pertama, hari ke delapan (tujuh hari pasca bilateral ooforektomi, pada masa early menopause) dan harike 36 (28 hari setelah auto transplantasi). Pengukuran kadar estradiol menggunakan rat estradiol ELISA kit. Analisis data menggunakan ANOVA test dan Post Hoc test pada SPSS (Software Package for Social Science). Hasil : Rerata kadar estradiol yang diukur pada hari ke 36 pada K1=15,889 ng/mL, pada K2=14,879 ng/mL dan pada K3=22,664 ng/mL. Tidak didapatkan perbedaan signifikan antara K1 dan K2 (p>0,05). Didapatkan perbedaan bermakna antara K1 dan K3 (p< 0,05), juga antara K2 dan K3 (p< 0,05). Hal ini menunjukkan terdapat pengaruh auto transplantasi pada kadar estradiol. Kesimpulan : Ada pengaruh auto transplantasi terhadap kadar estradiol pada tikus Wistar early menopause. Kadar estradiol pada kelompok dengan auto transplantasi meningkat sangat signifikan (p<0.05) dibandingkan dengan kelompok tanpa auto transplantasi.Kata Kunci : Kadar estradiol, Early menopause, Auto transplantasi
Improved Understanding of IUD and Implant Family Planning Acceptors in Family Planning Services at Solo Peduli Clinic Budihastuti, Uki Retno; Laqif, Abdurahman; Melinawati, Eriana; Prakosa, Teguh; Udiyanto, Hermawan; Priyanto, Heru; Darto, Darto; Ratnasari, Affi Angelia; Anggraeni, Asih; Prisasanti, Dympna Prameilita
Journal of Maternal and Child Health Vol 5, No 4 (2020)
Publisher : Journal of Maternal and Child Health

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Abstract

Background: Family planning acceptor's understanding of intra uterine device (IUD) and implant contracep­tion is still low, due to the lack of knowledge and negative percep­tions about IUD and im­plants contraception in the society. Therefore, it needs an effort to increase the understanding of family planning acceptors to reduce fertility rates through increasing the use of contraception. This study aimed to ana­lyze understanding and satisfac­tion of family planning acceptors with the satisfaction aspects of counseling, the comfort­able effect on the insertion of contraceptives, and the satis­faction of family planning services at the Solo Peduli Clinic.Subjects and Method: A cross sectional study was conducted at Solo Peduli Clinic, Surakarta, Central Java, from June to August 2020. A sample of 60 women divided into 2 groups: (1) 30 women who have used IUD and implant contraceptives, and (2) 30 women that will be given counselling and insertions of IUD and implant contraceptives. The study subject was selected by fixed disease sampling. The dependent variable was satisfaction. The independent variables were counselling, com­fortable effect, and family planning service. The data were collected by questionnaire and analyzed by a multiple logistic regression run on SPSS ver. 25.Results: The average level of satisfaction of counseling, the comfortable effect of using contraceptives, and satisfaction with family planning services has an "very satisfied". Good counselling (OR= 1.592; 95% CI= 1.097 to 2.310; p= 0.014), insertion conve­nience (OR= 1.428; 95% CI= 0.976 to 2.090; p= 0.066), and good family planning service (OR= 1.761; 95% CI= 1.191 to 2.603; p= 0.004) increased satisfaction.Conclusion: Good counselling, insertion convenience, and good family planning service increase satisfaction.Keywords: Family planning acceptors, IUD, implants, family planning servicesCorrespondence: Uki Retno Budihastuti. Department of Obste­trics and Gynecology, Dr. Moewardi Hospital/ Faculty of Medicine, Universitas Sebelas Maret, Jl. Kolonel Sutarto 132, Surakarta, Central Java. Email: ukiretno@staff.uns.ac.id. Mobile: 08122656140.Journal of Maternal and Child Health (2020), 05(04): 436-445https://doi.org/10.26911/thejmch.2020.05.04.11 
The Effect of Hypnotherapy on Postpartum Pain and Depression in Women with Post Caesarean Delivery Mahandaru, Araafi Hariza; Respati, Supriyadi Hari; Sulistyowati, Sri; Laqif, Abdurahman; Prasetya, Hanung
Indonesian Journal of Medicine Vol 6, No 2 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Postoperative pain is one of the most common problems in women after cesarean section. Caesarean section is also associated with post-partum depression. Hypno­therapy is one of the complementary therapy options that are effective and efficient in reducing pain symptoms and post-partum depression. This study aimed to analyze the effect of hypnotherapy on the level of pain and post-partum depression in post-cesarean section patients.Subjects and Method: This was an expe­rimental single-blind randomized controlled trial with a post-test group design, which was conducted from January to April 2021, at the Dr. Moewardi and Universitas Sebelas Maret Hospitals, Surakarta. A sample of 80 patients with cesarean section was divided into two groups, namely 40 pati­ents in the hypno­therapy group and 40 patients in the control group. The indepen­dent variable was hypno­therapy. The depen­dent variables were pain and depression. Hypnotherapy was carried out by self-hypnosis using audio recordings of hypnotherapy in 2 sessions before and after the cesarean section procedure. The pain was measured by the Numeric Rating Scale. Post-partum depression was measured by the Edinburgh Postnatal Depression Scale. The data were analyzed by an independent t-test.Results: Post-cesarean section pain in the group of hypnotherapy (Mean= 4.58; SD= 1.20) was lower than without hypnotherapy (Mean= 6.48; SD= 1.01), and it was statis­tically significant (p<0.001). Postpartum de-pression in the group of hypnothera­py (Mean= 6.08; SD= 1.60) was lower than non-hypnotherapy group (Mean= 8.48; SD= 3.78), and it was statis­tically significant (p <0.001).Conclusion: Hypnotherapy has a significant effect on reducing pain and post-partum depression in post-cesarean section patients.Keywords: Hypnotherapy, pain levels, post-partum depression, post-cesarean sectionCorrespondence: Araafi Hariza Mahandaru. Department of Obstetrics and Gynecology, Faculty of Medi­cine, Universitas Sebelas Maret/ Dr. Moe­wardi Hospital, Surakarta, Jl. Kolonel Sutar­to, Jebres, Surakarta 57126, Central Java. Email: mahandarurafi@gmail.com.Indonesian Journal of Medicine (2021), 06(02): 194-205https://doi.org/10.26911/theijmed.2021.06.02.08 
Apakah Endometriosis Mempengaruhi Kualitas Embryo pada Pasien Invitro Fertilization? Suryoningrat, Dewanto; Laqif, Abdurahman; Soetrisno, Soetrisno; Budihastuti, Uki Retno; Sulistyowati, Sri
JURNAL KESEHATAN REPRODUKSI Vol 8, No 1 (2021)
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkr.63039

Abstract

Latar Belakang Invitro Fertilization merupakan salah satu manajemen infertilitas yang baik, namun masih didapatkan adanya kesamaan peluang kegagalan perkembangan embrio sebanyak 50% dibandingkan dengan pasien yang tidak mengalami endometriosis.Tujuan: untuk mengetahui hubungan endometriosis dan kualitas embrio pada pasien yang menjalani program invitro fertilization.Metode: Data yang dikumpulkan merupakan data pada rekam medis pasien Klinik Fertilitas Sekar yang menjalani invitro fertilization di Klinik Fertilitas Sekar RSUD Dr. Moewardi Surakarta pada Januari 2010 – Desember 2019. Analisis menggunakan uji deskriptif dan Uji T tidak berpasangan. Hasil dianggap signifikan jika p ≤ 0,05.Hasil dan Pembahasan: Dalam penelitian ini, rerata kualitas embrio baik memiliki perbedaan yang signifikan (p<0.05) antara pasien dengan endometriosis dan pasien tanpa endometriosi, sedangkan kualitas embrio buruk tidak memiliki perbedaan yang signifikan (p>0.05).Kesimpulan: Endometriosis memiliki hubungan yang signifikan dengan kualitas embrio pada wanita yang menjalani program IVF.
Biopsychosocial Analysis of Factors on COVID-19 Screening Awareness of Infertile Couples in Assisted Reproductive Technology Budihastuti, Uki Retno; Laqif, Abdurahman; Melinawati, Eriana; Prakosa, Teguh; Udiyanto, Hermawan; Priyanto, Heru Priyanto; Darto, Darto; Rantasari, Affi Angelia; Wasyanto, Trisulo; Anggraeni, Asih; Wijayanti, Agung Sari
Journal of Maternal and Child Health Vol. 6 No. 5 (2021)
Publisher : Journal of Maternal and Child Health

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Abstract

Background: The development of screening methods for infertility patients during the Coronavirus-2019 (COVID-19) pandemic provides new challenges in the adaptation of children's want programs in the era of the COVID-19pandemic. Several screening methods have been developed but various factors affect the awareness of couples to want to do COVID-19 screening. This study aimed to analyze biopsychosocial factors associated with awareness of COVID-19 screening in infertile couples.Subjects and Method: A cross-sectional study conducted at The Sekar Polyclinic of Dr. Moewardi Regional General Hospital during the COVID-19 pandemic. A number of 60 infertile couple of reproductive age who underwent the ART program was selected by random sampling. The dependent variable was awareness for COVID-19 screening. The independent variables were anxiety, knowledge, age, and length of infertility. The data were obtained from medical record and questionnaire and analyzed by a multiple logistic regression.Results: Anxiety (OR= 26; 95% CI; p<0.001) and above-average knowledge levels (OR=16; 95% CI; p<0.001) affected awareness for COVID-19 screening. While the age and length of infertility do not affect awareness for COVID-19 screening (p >0.05).Conclusion: Anxiety and above-average knowledge levels affect awareness for COVID-19 screening.Keywords: biopsychosocial, COVID-19 screening, infertile, assisted reproductive technology.Correspondence:
Relationships between Smoking, Age, Body Mass Index, and Abstinence with DNA Fragmentation Index in Male Infertile Patients Ediningtyas, Atifa Nadira; Laqif, Abdurahman; Melinawati, Eriana; Respati, Supriyadi Hari
Journal of Maternal and Child Health Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Infertility increases annually, by 0.370% in women and 0.291% in men. One of the causes of male infertility is idiopathic in the form of cigarettes, alcohol, drugs, obesity, psychological stress, old age, dietary factors, and exposure to toxins in the environment or work. These factors can cause oxidative stress that can lead to sperm DNA damage or sperm DNA fragmentation as measured through the DNA Fragmentation Index (DFI). So this study to analyzed about the relationship between smoking, age, Body Mass Index, and abstinence period with DNA Fragmentation Index in infertile patient.Subjects and Method: This type of research is observational analytics with a cross-sectional approach. The study was conducted at the Sekar Clinic of Dr. Moewardi Hospital Surakarta. A total of 35 subjects of male infertility patients performed DNA examinations of sperm fragmentation. Inde