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All Journal GEMA TEKNOLOGI
Yudanto, Yusuf Arya
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Computer Science & IT

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EKSTRAKSI SENYAWA BIOAKTIF THEAFLAVIN TEH OOLONG (CAMELLIA SINESIS) DENGAN AIR SEBAGAI GREEN SOLVENT Amalia, Rizka; Yulianto, Mohamad Endy; Purwantisari, Susiana; Yudanto, Yusuf Arya; Pangestu, Ilyas Teguh
Gema Teknologi Vol 21, No 1 (2020): April 2020 - October 2020
Publisher : Vocational School Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/gt.v21i1.32287

Abstract

Theaflavin, a polyphenolic compounds found  in oolong tea and black tea, thought to have medicinal potency. Theaflavins and their derivatives such as theaflavin gallate have shown a broad spectrum of antiviral activity against several viruses, including influenza A, B and hepatitis C viruses. Previous research show that theaflavins could inhibit RdRp activity through blocking the active site in the catalytic pocket of RdRp in SARS‐CoV‐2, SARS‐CoV and MERS‐CoV.. This research aims to extract theaflavins in oolong tea with water solvent at a temperature of 100oC, pressure > 1 atm and varied extraction times (10-60 minutes). The effect of oolong tea extraction time towards the  theaflavin content was observed. The results showed that with the longer extraction time, the theaflavin levels were reduced due to the degradation of thermal theaflavins into thearubigins. The model exponential equation obtained is  y=14,91488 e-0,2631x + 0,11865, with the R2=0.99161. The best operating conditions was obtained at 10 minutes of extraction time, resulted in 1.19% of the total theaflavin content of oolong tea.
Co-Authors AGUS PURWANTO Budiyono Budiyono Fathurrahman, Hanif Muhammad Heny Kusumayanti Ida Hayu Dwimawanti Mohamad Endy Y Yulianto Pangestu, Ilyas Teguh Rizka Amalia Susiana Purwantisari Windyandari, Aulia Windyandari Yusim, Adi Kurniawan