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Histoid Leprosy Rinasari, Umi; Sawitri, Sawitri; Listiawan, M. Yulianto; Prakoeswa, Cita Rosita; Agusni, Indropo; Santoso, Rachmat; Izumi, Shinzo
Indonesian Journal of Tropical and Infectious Disease Vol. 1 No. 1 (2010)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (210.114 KB) | DOI: 10.20473/ijtid.v1i1.3719

Abstract

Histoid Leprosy is a variant of lepromatous leprosy with characteristic clinical and histopathological features. Usually it is occured in lepromatous patients who relaps after dapsone monotherapy, in those with dapsone resistance , sometimes even after multidrug treatment, or at times, de novo with characteristic clinical and histopathological features. A 36 years old male, originated from Papua, visited to the skin outpatient clinic with translucent shiny nodules on the left elbow and thumb for the last 18 months. The nodules were multiple, painless and firm. There were nasal congestion, tickening of ear lobes and loss of eye brows. Patient did not have any history of previous antileprotic treatment. Routine blood examination was normal. Bacteriological examination of slit skin smear revealed acid-fast bacilli of Bacterial Index 4+ and Morfologic Index 10%. Histopathology of skin suggested lepromatous leprosy of histoid type with characteristic interlacing bundles of spindle shaped cells. Anti-PGL1 antibody (ELISA) revealed high titer of IgM (>5.300 u/ml) and also IgG anti PGL-1 (>5.300 u/ml). Polymerase chain reaction examination test to detect M.leprae was positive and direct sequencing of M.leprae isolate shows no mutation, which means no resistancy to MDT treatment. Treatment with MDTWHO regiment give clinical improvements and the histoid lesions disappered after 3 months treatment.The histoid form of leprosy in this case developed without any prior treatment of anti leprotic drugs ( de novo ). Some theoretical aspects of the patho-mechanism of histoid leprosy are discussed.
PREFERENSI MINAT MAHASISWA FEB UNSOED NASABAH PERBANKAN SYARIAH DALAM MENGGUNAKAN JASA PERBANKAN SYARIAH Santoso, Rachmat; Ahmad, Abdul Aziz; Arintoko, Arintoko
Indonesian Journal of Islamic Business and Economics (IJIBE) Vol 4 No 1 (2022): IJIBE
Publisher : Islamic Economic Scholar Association and Faculty of Economics and Business Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32424/1.ijibe.2022.4.1.8737

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh variabel biaya, pendapatan, pelayanan, lokasi, dan bagi hasil terhadap minat mahasiswa Fakultas Ekonomi dan Bisnis Universitas Jenderal Soedirman Purwokerto yang merupakan nasabah perbankan syariah untuk menggunakan jasa perbankan syariah. Penelitian ini menggunakan sampel sebanyak 103 nasabah mahasiswa. Pengambilan sampel menggunakan rumus Zikmund. Hasil analisis menunjukkan bahwa variabel rendahnya biaya, pendapatan, pelayanan, lokasi dan bagi hasil berpengaruh terhadap minat mahasiswa menggunakan perbankan syariah. Kemudian variabel yang paling penting untuk preferensi minat mahasiswa menggunakan perbankan syariah adalah variabel pelayanan.