Yulyani Nur Azizah
Department Of Chemistry, Science And Technology Faculty, Syarif Hidayatullah Islamic State University, South Tangerang, 15412, Indonesia

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Facial Mask Formulation Enriched with Moringa Leaves (Moringa oleifera) Extract and Their Activity as Antioxidants and Antibacterials Hendrawati Hendrawati; Yulyani Nur Azizah; Niah Kusuma Hapsari
Jurnal Kimia Valensi Jurnal Kimia VALENSI Volume 6, No. 2, November 2020
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v6i2.16982

Abstract

Moringa leaves (Moringa oleifera) are useful for skin health as an additional ingredient for cosmetics, such as facial mask. This study aims to determine the optimum formula of Moringa leaves extract in powder mask, evaluate its activity as an antioxidant and antibacterial, while also ascertaining its characteristics, based on the quality requirements of SNI 16-6070-1999 and SNI 16-4399-1996 for cosmetics and skin moisturizers, respectively. Facial mask formula was made through various concentrations of Moringa leaves methanol extract 12.5%, 17.5%, 25%, and 35%, with its optimum formulation determined by panelists’ preference level, based on organoleptic test results. Furthermore, the antioxidant activity was carried out, using the 1,1-diphenyl-2-picrylhydrazil (DPPH) method, while that of the antibacterial towards Staphylococcus aureus bacteria was performed, through the use of the diffusion technique, with the active compound also being analyzed, using GC-MS (Gas Chromatography-Mass Spectrophotometry). The results however, showed that the antioxidant and antibacterial activities in the facial mask formula were lower than when in their extract form. The facial mask formula with the addition of 35% Moringa leaves extract (F4), had the highest inhibitory value of 66,04%, while the antibacterial activity against S. aureus occured at concentrations ≥ 0.125 g/mL. Also, the result of GC-MS analysis of Moringa leaves extract, showed quinic (peak 7, Rt = 21,165 minutes) and linoleic acid as the highest peak (peak 12, Rt = 29,439 minutes). Based on panelists' preference level, the result of Anova and Duncan Test analysis showed that the most optimum facial mask product was with 17.5% Moringa leaves extract (F2), with a score of 3.29. Therefore, all characterization of mask formula with 12.5%, 17.5%, 25%, and 35% additional amount of Moringa leaves extract, have met up with the requirements for SNI 16-6070-1999 and SNI 16-4380-1996 criterias, together with the pH value of 5.45 - 6.02, specific gravity 1 g/mL, emulsion stability 96.57 - 97.05%, and negative microbial contamination.
Synthesis, Characterization and Antioxidant Activity of Kobalt (II)-Hydrazone Complex Yulyani Nur Azizah; Irma Mulyani; Deana Wahyuningrum; Damar Nurwahyu Bima
EduChemia (Jurnal Kimia dan Pendidikan) Vol 5, No 2 (2020)
Publisher : Department of Chemical Education Faculty of Teacher Training and Education Universitas Su

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (623.189 KB) | DOI: 10.30870/educhemia.v5i2.7987

Abstract

The potency of the first-row transition metal complexes with Schiff's base ligand as an antioxidant has been widely studied by researchers. In this study, hydrazone-type Schiff base compounds, salicylaldehyde-2,4-dinitrophenylhydrazone (SDPH), resulted from the condensation of salicylaldehyde (1.5 mmol) and 2,4-dinitrophenylhydrazine (1.5 mmol) were synthesized and characterized with 1H-NMR. The synthesized SDPH was used as ligands in the formation of Co(II) metal complexes. The Co(II)-SDPH complexes were synthesized with reflux reaction at 60oC for 6 hours in molar ratio 1:3. Triethylamine is used to synthesis Co(II)-SDPH, which serves to deprotonate SDPH ligands. ESI-MS analysis showed that the complex is a neutral dimeric complex.The complex has the chemical formula [Co2(SDPH)2[(Et)3N]2(acn)2(OH)2} ([M+Na]+ = 1061 g/ mol), shown on the ESI-MS spectrum. Coordinate bonds between Co (II) metal ions with ligands are observed in the presence of shifting of the C=N wave number, as well as the loss of the vibrating peaks of the O-H groups to the infrared spectra of complexes. The IR spectrum of complexes was suggested that SDPH behave as a bidentate ligand through the azomethine nitrogen atom and phenolic oxygen atom. The ligand and its Co(II) complex have been screened for antioxidant activity against DPPH (2,2-diphenyl-1-picrylhydrazine). Based on the activity test results, the IC50 value of Co(II)-SDPH complex was lower than ligand. These results show that Co(II)-SDPH are potentials as antioxidants.
Physico-Chemical Characteristics of Lampung Natural Zeolite Functionalized Mercapto-Silane Yulyani Nur Azizah; Faizal Rachman
EduChemia (Jurnal Kimia dan Pendidikan) Vol 8, No 1 (2023)
Publisher : Department of Chemical Education Faculty of Teacher Training and Education Universitas Su

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30870/educhemia.v8i1.18514

Abstract

Lampung natural zeolite (ZAL) is a potential adsorbent for metal pollutants.However, its adsorption capacity is still low due to the presence of impurities that cover the pores and active sites on its surface. To improve the adsorption performance, especially on soft acid Lewis metals/cations, ZAL needs to be activated and functionalized with organosilanes containing thiol groups (-SH) as soft Lewis bases such as (3-mercaptopropyl) trimethoxysilane (MPTMS). This study aims to determine the physicochemical properties of organosilane-modified natural zeolites. The MPTMS silanization process in ethanol: water (1:1, v/v) media was carried out on ZAL activated with 1 M HCl. Qualitatively, the success of the functionalization can be directly observed from the dispersion of the zeolite in organic and aqueous phases, where the hydrophobicity of the silane-modified zeolite (ZM-EA) increased compared to the natural zeolite. The functional group analysis results showed typical peaks of S-H and C-H at 2554 and 2930 cm-1. MPTMS functionalization produced five peaks of the typical diffraction pattern of clinoptilolite at 2θ: 10,4o; 17,8o; 22,8o; 28,3o; 30,5o; dan 32,4o. SEM-EDX results on ZM-EA showed the presence of a sulfur component of 4.75% (% At) with a Si/Al ratio >7.