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Formulasi Fast Disintegrating Tablet Ekstrak Etanol Avicennia marina fructus dengan Metode Granulasi Basah Mia Fitriana; Muhammad Habibie; Abidzar Mirza; Rafli Al Anshari
Jurnal Pharmascience Vol 9, No 1 (2022): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v9i1.12853

Abstract

Avicennia marina fructus mengandung kandungan senyawa berupa alkaloid, flavonoid, saponin, glikosida yang terbukti memiliki aktivitas antidiabetes. Prevalensi diabetes melitus semakin meningkat pada pasien geriatri. Pasien geriatri cenderung mengalami kesulitan menelan tablet konvensional sehingga perlu dibuat sediaan yang lebih cepat hancur seperti fast disintegrating tablet. Salah satu metode granulasi yang dapat digunakan untuk membuat fast disintegrating tablet adalah menggunakan metode granulasi basah.  Penelitian ini bertujuan untuk Penelitian ini bertujuan untuk menentukan formula fast disintegrating tablet yang memilik sifat fisika yang baik.Ekstraksi dilakukan dengan metode maserasi.  Tiga formula dibuat dengan memvariasikan bahan penghancur yakni explotab®. Serbuk sediaan dievaluasi laju alir, sudut diam dan bobot jenis benar. Sediaan tablet dilakukan evaluasi keseragaman bobot dan waktu hancur. Hasil menunjukkan bahwa ketiga formula memenuhi syarat pada evaluasi granul laju alir, sudut diam dan bobot jenis benar dan uji evaluasi keseragaman bobot tablet. Formula I dan III tidak memenuhi syarat uji waktu hancur tablet, sedangkan formula II memenuhi syarat waktu hancur fast disintegrating tablet yang baik. Kesimpulan dari penelitian ini adalah formula yang menghasilkan sifat fisik sediaan yang baik adalah formula II dengan komposisi ekstrak A. marina fructus 2,5%, explotab® 6%, magnesium stearat 2,5 %, aerosil 0,5%, talkum 0,5%, gelatin 0,1%, dan manitol 87,9%. Kata Kunci: Fast Disintegrating Tablet, Evaluasi, Diabetes   Avicennia marina fructus contains compounds in the form of alkaloids, flavonoids, saponins, glycosides which are proven to have antidiabetic activity. The prevalence of diabetes mellitus has been increasing in geriatric patients. Geriatric patients tend to have difficulty swallowing conventional tablets, so it is necessary to make preparations that disintegrate more quickly, such as fast disintegrating tablets. One of the granulation methods that can be used to make fast disintegrating tablets is the wet granulation method. The purpose of this study was to determine the formula for fast disintegrating tablets that had good physical properties. Extraction was carried out by the maceration method. Three formulas were made by varying the disintegrator agent, namely explotab®. The granule preparations were evaluated for flow rate, angle of repose and the density. The tablet preparations were evaluated for weight uniformity and disintegration time. The results showed that the three formulas met the requirements for evaluating the granule flow rate, angle of repose and the density and the weight uniformity of tablet. Formula I and III did not meet the requirements for the disintegration time of tablets, while formula II met the requirements for a good disintegrating time for fast disintegrating tablets. The conclusion of this research was the formula that produced good physical properties of the preparation was formula II with a composition of 2.5% A. marina fructus extract, 6% explotab®, 2.5% magnesium stearate, 0.5% aerosil, 0.5% talc, 0.1% gelatin and 87.9% mannitol.
Prinsip Komunikasi Islam Sebagai Etika Bermedia Sosial Muhammad Ilmi Saggaf; Muhammad Wildan Arif; Muhammad Habibie; Khairul Atqiya
Journal of Communication Studies Vol 1 No 01 (2021): JCS: Journal of Communication Studies
Publisher : Program Studi Komunikasi dan Penyiaran Islam, Fakultas Dakwah, Institut Agama Islam Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1027.911 KB) | DOI: 10.37680/jcs.v1i01.698

Abstract

In the era of globalization, the process of delivering a message and receiving it is so fast and easy. This is evidenced by the existence of social networking applications that are present on smartphones. The use of social media is very diverse, so that many people, ranging from ordinary people to journalists, can spread what they want. However, unfortunately, sometimes there are those who spread information on social media who do not pay attention to communication ethics, causing untrue news such as hoaxes, defamation, denunciation, etc. all of which are out of the realm of ethics. Whereas in Islam really uphold ethics in communication and prioritize ethics. And in principle, it leads people to experience a peaceful and comfortable life. So as media users must apply ethics, one of these ethics is the principle of Islamic communication, in which this communication has four main points, namely; honest, positive message, tabayyun and silm. Which Islamic communication has two main sources, namely the Al-Quran and As-Sunnah.
PENERAPAN PERATURAN DAERAH NOMOR 14 TAHUN 2015 TENTANG PENYELENGGARAAN KEBERSIHAN, KEINDAHAN, KETERTIBAN DAN KESEHATAN LINGKUNGAN TERHADAP FENOMENA BADUT ANAK DI KOTA BANJARMASIN Muhammad Habibie; Nahdhah Nahdhah
Jantera Hukum Bornea Vol. 5 No. 01 (2022): Januari 2022
Publisher : Fakultas Hukum UVAYA Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (507.322 KB)

Abstract

Peningkatan pertumbuhan penduduk dan semakin berkembangnya Kota Banjarmasin dari tahun ke tahun maka berimbas pula dalam hal pekerjaan dan semakin banyak persaingan ditambah lagi pandemi covid-19 sehingga banyaknya pengangguran dan kesenjangan ekonomi yang tidak terbendung. Maka banyak anak bekerja sebagai pengamen, badut anak, dan pengemis guna membantu perekonomian keluarga mereka. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang menyebabkan maraknya badut anak di jalanan Kota Banjarmasin dan upaya pemerintah untuk menertibkan badut anak berdasarkan Peraturan Daerah Nomor 14 Tahun 2015 Tentang Kebersihan, Keindahan, Ketertiban, dan Kesehatan Lingkungan terhadap fenomena badut anak di Kota Banjarmasin. Metode penelitian yang digunakan adalah metode empiris. Sumber data dipilih secara purposive sampling. Pengumpulan data dilakukan dengan teknik observasi, wawancara dan dokumentasi. Analisis hasil penelitian menggunakan langkah-langkah reduksi data dan verification. Hasil penelitian menunjukkan bahwa maraknya badut anak di Kota Banjarmasin disebabkan karena faktor ekonomi untuk membantu orang tua mereka. Upaya yang dilakukan pemerintah untuk menertibkan badut anak berdasarkan Peraturan Daerah Nomor 14 Tahun 2015 Tentang Kebersihan, Keindahan, Ketertiban, dan Kesehatan Lingkungan dalam Pasal 14 Ayat (3) Huruf A melalui razia secara berkala disepanjang jalan Kota Banjarmasin. Kemudian mereka dibawa ke Rumah Singgah Dinas Sosial dan Dinas Pemberdayaan Perempuan dan Perlindungan Anak Kota Banjarmasin untuk dilakukan pembinaan. Penertiban sudah dilaksanakan secara maksimal dan optimal, akan tetapi belum mampu mengurangi jumlah badut anak jalanan di Kota Banjarmasin. Beberapa kendala yang dihadapi dalam penerapan Peraturan Daerah tersebut dalam hal penertiban badut anak sifatnya masih umum dan tidak mengatur ketentuan sanksi pelanggaran terhadap Pasal 14 Ayat (3) Huruf A untuk badut anak
Keterampilan Dasar Melempar, Menangkap, Dan Memukul Bola Pada Siswa Kelas Iv SD Negeri Kebun Bunga 1 Banjarmasin Muhammad Habibie; Ari Tri Fitrianto
Aisyah Journal Of Physical Education (AJoPE) e-ISSN : 3046-790X Vol. 2 No. 1 (2023): Aisyah Journal Of Physical Education (AJoPE)
Publisher : Universitas Aisyah Pringsewu

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Abstract

The purpose of this study was to find out how high the level of basic skills in throwing, catching, and hitting the ball in grade IV students of SD Negri 1 Kebun Bunga, Banjarmasin. Academic Year 2022/2023. The research method uses observation techniques and test techniques which are carried out practically, namely the practice of basic movement abilities with small ball games. Researchers observed children's activities in the learning process in cycles one and two. While the test results data obtained from tests conducted at the end of learning. The research procedure was carried out in accordance with the research put forward by (Widyatmoko, 2016) "The stages carried out in each research cycle include: planning stage, action stage, observing stage, and reflecting stage. These steps constitute a single action unit which is referred to as a cycle of action. The results of the research using observation techniques and practical test techniques. Get an increase in basic movement abilities. As for the increase in students' basic movement abilities with an average value of cycle I was 77.5 while the average value of cycle II was 87. The increase in the average value of cycle I to cycle II was 10.5. The benefits of this research for the general public as the development of insight into learning activities and for teachers as an alternative in the use of small ball games in physical education learning.