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All Journal JURNAL INFO KESEHATAN Klinikal Sains (Jurnal Analis Kesehatan) INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Jurnal Ners Jurnal teknologi Kesehatan Borneo MAHESA : Malahayati Health Student Journal Jurnal EduHealth JURNAL ILMIAH GLOBAL EDUCATION Innovative: Journal Of Social Science Research Jurnal Vokasi Kesehatan Jurnal Laboratorium Khatulistiwa Jurnal Ilmiah Global Education
Ari Nuswantoro
Poltekkes Kemenkes Pontianak
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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AKTIVITAS ANTIBAKTERI EKSTRAK DAUN KITOLOD (Isotoma longiflora) TERHADAP PERTUMBUHAN BAKTERI Streptococcus pyogenes Ari Nuswantoro; Kartini Kartini
Klinikal Sains : Jurnal Analis Kesehatan Vol 11 No 2 (2023): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v11i2.3343

Abstract

Kitolod is a plant that is easy to grow in the tropics, including Indonesia. Kitolod leaves contain flavonoids, alkaloids, tannins, saponins and terpenoids that have the potential to be used as antibacterial agents to inhibit the growth of pathogenic bacteria such as Streptococcus pyogenes. This study aims to determine the antibacterial activity of kitolod leaf extract on the growth of Streptococcus pyogenes. This research is quasi-experimental with purposive sampling technique. Kitolod leaves were extracted by maceration method using ethanol then dissolved in 15% DMSO to obtain concentrations of 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, and 90%. Each concentration was replicated three times, and the control used the antibiotic bacitracin. After carrying out the antimicrobial sensitivity test using the Kirby-Bauer diffusion method, the results obtained were inhibition zones of 17.66 mm (sensitive), 18.16 mm (sensitive), 18.50 mm (sensitive), 19 mm (sensitive), 19. 83 mm (sensitive), 21.16 mm (sensitive), 21.83 mm (sensitive), 22.33 mm (sensitive), and 23.83 mm (sensitive) respectively, while the bacitracin control was 17.5 mm (sensitive). Thus, kitolod leaf extract proved to have antibacterial activity against the growth of Streptococcus pyogenes.
Resistance Profile Antibiotics Pathogenic Bacteria from SWAB Wounds of Pontianak City Diabetes Treatment Clinic Patients Azura azura; Sri Tumpuk; Ari Nuswantoro
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diabetes mellitus (DM) is a type of metabolic disorder where the sufferer has high blood sugar levels due to the body's failure to respond or produces insufficient amounts of insulin, or a metabolic disorder caused by hyperglycemia due to abnormalities in insulin secretion and insulin action or both. One of the complications of diabetes is ulcers, where a superficial infection occurs on the sufferer's skin and becomes a strategic location for bacterial growth. Most of the drugs that are widely used to inhibit or kill bacteria that cause infections in humans are antibiotics which carry the risk of drug resistance. Antibiotic resistance is a growing problem in many parts of the world. Antibiotic resistance can occur due to inappropriate or excessive use of antibiotics. This study aims to determine the susceptibility of pathogenic bacteria to several antimicrobial agents or antibiotics and to determine the percentage of antibiotic resistance in diabetes mellitus patients who experience complications, which will make it easier to choose the right antibiotic for healing. This research uses a descriptive method using samples of bacterial isolates which have been identified as 11 samples of Staphylococcus aureus bacterial isolates, 11 samples of Pseudomonas aeruginosa isolates and 39 samples of Klebsiella pneumoniae bacterial isolates. Antimicrobial susceptibility test (AST) disk diffusion method (Kirby & Bauer test) using Mueller Hinton media. With eight different types of antibiotics, this test was carried out to prove antimicrobial activity by measuring the diameter of the antimicrobial activity inhibition zone. Resistance test results were obtained in Staphylococcus aureus experiencing the highest resistance to the antibiotic Gentamycin (CN) at 63.63%, in Pseudomonas aeruginosa experiencing high resistance to the antibiotic Ampicillin (AMP) at 54.54%, and in Klebsiella pneumoniae experiencing the highest resistance. against the antibiotic Ampicillin (AMP) was 41.02%. Preventing antibiotic resistance in wound healing is very important to ensure antibiotics remain effective in treating infections. Therefore, this research was carried out in order to determine the correct type of antibiotic for healing wounds in diabetes mellitus sufferers.
Normal dan Dislipidemia: Profil Lipid Pasien Hipertensi- Prolanis di Kota Pontianak Sharen Sen; Ari Nuswantoro; Laila Kamilla; Dinasti Aprilia
MAHESA : Malahayati Health Student Journal Vol 4, No 1 (2024): Volume 4 Nomor 1 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i1.13266

Abstract

ABSTRACT The primary cause of cardiovascular disease (CVD) is hypertension (HT). Through the Prolanis program, BPJS treats HT patients in Indonesia through various activities, including physical activity and monitoring lipid profiles, which until now have not been widely reported. The aim of this study was to describe the lipid profile of HT patients participating in Prolanis in Pontianak City. The samples are the medical records from 110 patients chosen using the total sampling method in 2022 at the Unit Pelaksana Teknis Pusat Laboratorium Kesehatan Kota Pontianak. Information gathered from 99 women and 11 men revealed that 80.8% of the women had hypercholesterolemia; triglycerides and HDL were mainly within normal ranges; LDL ranged from normal (13.6%) to extremely high (8.2%); and the ratios of cholesterol to HDL and triglycerides to HDL were mainly normal. One of the Prolanis program's goals, physical exercise, appears to have an impact on the patient's typical lipid profile. Nonetheless, the fact that some people have dyslipidemia raises awareness of the risk of CVD and supports the necessity of keeping this program in place. Keywords: Cardiovascular Disease, Lipid Profile, Hypertensive Patients, Prolanis  ABSTRAK Penyebab utama penyakit kardiovaskular (CVD) adalah hipertensi (HT). Melalui program Prolanis, BPJS menangani pasien HT di Indonesia melalui berbagai kegiatan, termasuk aktivitas fisik dan pemantauan profil lipid, yang hingga saat ini belum banyak dilaporkan. Tujuan dari penelitian ini adalah untuk mendeskripsikan profil lipid pasien HT yang mengikuti Prolanis di Kota Pontianak. Sampel penelitian ini adalah rekam medis dari 110 pasien yang dipilih dengan menggunakan metode total sampling pada tahun 2022 di Unit Pelaksana Teknis Pusat Laboratorium Kesehatan Kota Pontianak. Informasi yang dikumpulkan dari 99 wanita dan 11 pria menunjukkan bahwa 80,8% wanita mengalami hiperkolesterolemia; trigliserida dan HDL sebagian besar dalam kisaran normal; LDL berkisar dari normal (13,6%) hingga sangat tinggi (8,2%); dan rasio kolesterol terhadap HDL serta trigliserida terhadap HDL sebagian besar dalam kisaran normal. Salah satu tujuan program Prolanis, yaitu latihan fisik, tampaknya berdampak pada profil lipid pasien. Meskipun demikian, fakta bahwa beberapa orang memiliki dislipidemia meningkatkan kesadaran akan risiko CVD dan mendukung perlunya mempertahankan program ini. Kata Kunci: Penyakit Kardiovaskular, Profil Lipid, Pasien Hipertensi, Prolanis
IDENTIFIKASI DAN PROFIL RESISTENSI BAKTERI PADA MINUMAN AIR TAHU DAN AIR TEBU DI WILAYAH KOTA PONTIANAK Aditia Aditia; Ari Nuswantoro; Herlinda Djohan; Bagus Muhammad Ihsan; Nurul Uq'ma; Anisya Nur Shafitri; Affifatuzahara Affifatuzahara; Fahma Ajeng Al-qorifah; Benedikta Anjelica
Jurnal Ilmiah Global Education Vol. 4 No. 4 (2023): JURNAL ILMIAH GLOBAL EDUCATION, Volume 4 Nomor 4, Desember 2023
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/jige.v4i4.1860

Abstract

Tofu and sugarcane juice drinks are in great demand because they taste delicious and affordable. These drinks can be contaminated with pathogenic bacteria due to hygiene and poor environment. Contamination of pathogenic bacteria that are resistant to antibiotics is a serious health threat.  The objective of this study is to identify and provide antibiotic resistance bacteria from tofu and sugarcane juice drinks overview. This Study is a descriptive-observation with a cross-sectional design. Bacterial identification is carried out by culture, while resistance testing is carried out by Kirby-Bauer. Penicillin, amoxicillin, ampicillin, ciprofloxacin, chloramphenicol, gentamicin, tetracycline, and vancomycin were used. 43 samples of tofu water drink and 70 samples of sugarcane juice drink were selected by purposive sampling. Staphylococcus aureus, Salmonella typhi, Enterobacter aerogenes, and Klebsiella pneumoniae founds in tofu drinks, while Enterobacter aerogenes, Salmonella typhi, Shigella dysenteriae, and Escherichia coli founds in sugarcane juice. Staphylococcus aureus resistant to penicillin (100%), Salmonella typhi resistant to penicillin (66.6%), Enterobacter aerogenes resistant to tetracycline (70%), Klebsiella pneumoniae resistant to penicillin (100%), Shigella dysenteriae resistant to ampicillin and gentamicin (100%), and Escherichia coli resistant to vancomycin (100%). Pathogenic-resistant bacteria in tofu and sugarcane juice drinks show the risk of spreading resistant bacteria which can trigger bacterial resistance with a wider spectrum.
Gambaran Kadar Glukosa Darah Sewaktu Pada Ibu Hamil di Puskesmas Tambelan Sampit Kota Pontianak Aditiya Ramadan; Ari Nuswantoro; Linda Triana; Bagus Muhammad Ihsan
Jurnal Ners Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v8i1.22203

Abstract

characterised by high blood sugar levels as well as problems with protein, lipid, and carbohydrate metabolism as a result of inadequate insulin activity. Patients who have wounds infected by pathogenic bacteria, both Gram positive and Gram negative, run the risk of developing a number of problems, including neuropathy, hypertension, coronary heart disease, retinopathy, nephropathy, and gangrene. This cross-sectional, observational, descriptive study aims to pinpoint pathogenic bacteria in the diabetic patients' wounds at the diabetes wound care clinic in Pontianak City. The bacterial identification stage includes inoculation on enrichment media, Gram staining, inoculation and observation of colonies on differential-selective media, and biochemical tests. Examination results showed that Klebsiella pneumoniae was identified in 20 samples (57%), Pseudomonas aeruginosa in 8 samples (23%), and Staphylococcus aureus in 7 samples (20%). According to the study, diabetic wound problems put DM patients at risk of contracting dangerous microorganisms and spreading them to others. In order to prevent infection and other health issues, patients are instructed on how to properly care for their wounds. They are also provided the correct follow-up by medical professionals.
Co-Authors Aditia Aditia Aditiya Ramadan Affifatuzahara Affifatuzahara Anisya Nur Shafitri Azura azura Bagus Muhammad Ihsan Benedikta Anjelica Desi Wahyumarniasari Devi Nurfitri Bintang Dinasti Aprilia Dinasti Aprillia Dinasti Aprillia Dinasti Aprillia Edy Suwandi Edy Suwandi Fahma Ajeng Al-qorifah Gervacia Jenny Ratnawati Herlinda Djohan Indah Purwaningsih Jessica Ningtyas Berlianti Juliana Cristyaningsih Kartini Kartini Laila Kamilla Linda Triana Maulidiyah Salim Natasya Intan Ramadhani Nur Reza Nurul Uq'ma P Purwanto Ratih Indrawati Rizki Zanuba Arifah Sharen Sen Slamet Sri Tumpuk Sugito Sugito Sugito Sugito