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All Journal Majalah Kedokteran Gigi Indonesia ODONTO Dental Journal Odonto dental journal
Vincensia Maria Karina
Department Of Periodontics, Faculty Of Dentistry, Universitas Gadjah Mada, Yogyakarta
Dentistry Health Professions Medicine & Pharmacology

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DIFFERENCES IN EFFECTIVENESS OF OCIMUM-SANCTUM 4% GEL AND 25% METRONIDAZOLE GEL POST SCALING ROOT-PLANING IN CHRONIC PERIODONTITIS Vincensia Maria Karina; Sri Pramestri Lastianny; Rina Meiliyanawaty
ODONTO : Dental Journal Vol 8, No 1 (2021): July 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.8.1.141-146

Abstract

Background: Chronic periodontitis is a disease that causes inflammation of the tooth supporting tissue, loss of periodontal attachment, and loss of alveolar bone. Root planning scaling treatment is carried out to remove irritants and microorganisms. The use of additional materials is required when the pocket depth is more than 5 mm. One of the herbal ingredients that has the potential as an adjunct to periodontal therapy is the 4% ocinumsanctum.Method: The sample consisted of 20 periodontal pockets with a depth of 4-6 mm which were given scaling root planning which were divided into two groups, namely 10 pockets given 4% maximum sanctum gel and 10 pockets given Metronidazole gel 25%. evaluations of the papillary bleeding index, TNF-α, and IL-β were performed at baseline, and on day 21. TNF-α and IL-β levels were taken through the gingival sulcus fluid and then tested using ELISA.Result: Papillary bleeding index, TNF-α, and IL-β levels showed a significant reduction in both groups but there was no significant difference between the 4% ocimum sanctum group and Metronidazole gel.Conclusion: ocimum sanctum application 4% post scaling root planning was able to lower papillary bleeding index score, TNF-α levels, and IL-β.
Effect of the application of curcumin (Curcuma Longa) oral gel on periodontal inflammation in patients with type 2 diabetes melitus Nur Rahman Ahmad Seno Aji; Vincensia Maria Karina; Osa Amila Hafiyyah; Kwartarini Murdiastuti; Ahmad Syaify
Majalah Kedokteran Gigi Indonesia Vol 7, No 3 (2021): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.69036

Abstract

Patients with Type 2 Diabetes mellitus (T2DM) were more prone to suffer from periodontitis due to unique alteration in host immune response. Application of curcumin oral gel as adjunctive therapy was expected to improve periodontal condition due to its anti-inflammatory properties. The objective of this study was to evaluate the effect of curcumin oral gel on periodontal inflammation in patients with T2DM. Sixteen periodontal pockets (n=16) from patients with T2DM were administered with curcumin oral gel using blunt cannula after periodontal curettage. Gingival Index (GI) and Periodontal Pocket Probing Depth (PPD) were evaluated a month after application. GI was assessed using visible sign of inflammation parameters including swelling, redness and bleeding upon probing. PPD was assessed using UNC-15 periodontal probe. The results were analyzed by Wilcoxon test (two related samples). The results showed that GI before treatment decreased by 51.61% a month post application. There was statistically significant difference (Sig 0.003) between GI mean before and after curcumin application. PPD decreased by 42.81% and showed statistically significant difference (Sig 0.000) by Wilcoxon Test. It is concluded that application of curcumin oral gel post curettage could decrease periodontal inflammation in patients with T2DM.
DIFFERENCES IN EFFECTIVENESS OF OCIMUM-SANCTUM 4% GEL AND 25% METRONIDAZOLE GEL POST SCALING ROOT-PLANING IN CHRONIC PERIODONTITIS Vincensia Maria Karina; Sri Pramestri Lastianny; Rina Meiliyanawaty
Odonto : Dental Journal Vol 8, No 1 (2021): July 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (433.76 KB) | DOI: 10.30659/odj.8.1.141-146

Abstract

Background: Chronic periodontitis is a disease that causes inflammation of the tooth supporting tissue, loss of periodontal attachment, and loss of alveolar bone. Root planning scaling treatment is carried out to remove irritants and microorganisms. The use of additional materials is required when the pocket depth is more than 5 mm. One of the herbal ingredients that has the potential as an adjunct to periodontal therapy is the 4% ocinumsanctum.Method: The sample consisted of 20 periodontal pockets with a depth of 4-6 mm which were given scaling root planning which were divided into two groups, namely 10 pockets given 4% maximum sanctum gel and 10 pockets given Metronidazole gel 25%. evaluations of the papillary bleeding index, TNF-α, and IL-β were performed at baseline, and on day 21. TNF-α and IL-β levels were taken through the gingival sulcus fluid and then tested using ELISA.Result: Papillary bleeding index, TNF-α, and IL-β levels showed a significant reduction in both groups but there was no significant difference between the 4% ocimum sanctum group and Metronidazole gel.Conclusion: ocimum sanctum application 4% post scaling root planning was able to lower papillary bleeding index score, TNF-α levels, and IL-β.
Co-Authors Ahmad Syaify, Ahmad Kwartarini Murdiastuti Nur Rahman Ahmad Seno Aji Osa Amila Hafiyyah Rina Meiliyanawaty Sri Pramestri Lastianny, Sri Pramestri