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Giant Lipoma of The Breast: Special Clinical Finding Abdul Hafiz, Muhammad Zaki; Daan khambri; Anandia Putriyuni
Biomedical Journal of Indonesia Vol. 7 No. 2 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i2.296

Abstract

Lipomas are the most common benign tumors of mesenchymal origin.Lipoma of breast is somewhat difficult to diagnose clinically because of fattyconsistency of breast. Giant lipoma is the mass of lipoma that exceeds atleast 10 cm in one dimension or weighs a minimum of 1000 gr.Only veryfew case reports giant lipoma of the breast available in literature becauserarity in size and location. Due to the fatty composition of the breast,difficulties in diagnosis, threatment, and reconstruction are oftenencountered.Presently, we have reported a case of this rare entity in 49years old female with giant tumor of the left breast that most of its mass,causing breast asymmetry and feel heavy. The operative finding: looks likelipoma between pectoralis major muscle and pectoralis minor muscle witha diameter of 31 cm and weighs 3.1 kg. After excision the tumor we need tomammoplasty.Pathology anatomy examination showed a lipoma.
ADENOKARSINOMA PROSTAT: PENILAIAN PROGNOSTIK DAN DERAJAT HISTOPATOLOGI Anandia Putriyuni; Noza Hilbertina
Majalah Kedokteran Andalas Vol 37, No 2 (2014): Published in September 2014
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (615.516 KB) | DOI: 10.22338/mka.v37.i2.p93-100.2014

Abstract

AbstrakKanker prostat merupakan kanker kedua terbanyak pada pria di seluruh dunia. Tujuan penelitian ini adalah untuk mengetahui faktor prognostik adenokarsinoma prostat seperti derajat histopatologi berdasarkan the 2005 ISUP modified Gleason system, invasi perineural dan kadar PSA serum sebelum operasi. Ini adalah suatu penelitian deskriptif kasus adenokarsinoma prostat yang didiagnosis di laboratorium patologi anatomi periode 2010-2012. Data usia dan kadar PSA diperoleh dari rekam medik. Review sediaan histopatologi dilakukan untuk konfirmasi skor Gleason, lalu dikelompokan berdasarkan derajat histopatologi. Kasus adenokarsinoma prostat yang memenuhi kriteria inklusi adalah 163. Hasil penelitian menunjukkan kasus adenokarsinoma prostat terbanyak pada kelompok usia 61-70 tahun sebanyak 38,65%, derajat histopatologi poorly differentiated yaitu 46,63%, invasi perineural 22,7% dan 83,33% kadar PSA serum >20 ng/ml. Pada kelompok usia 51-60 tahun adenokarsinoma prostat terbanyak ditemukan dengan derajat histopatologi well differentiated; sedangkan kelompok usia 61-70 tahun, 71-80 tahun dan 81-90 tahun terbanyak poorly differentiated. Invasi perineural positif terbanyak pada derajat histopatologi poorly differentiated. Semua derajat histopatologi adenokarsinoma prostat menunjukkan kadar PSA serum terbanyak >20 ng/ml. Penelitian ini menunjukkan kecenderungan peningkatan usia, invasi perineural dan kasus dengan kadar PSA serum >20 ng/ml bersamaan dengan peningkatan derajat histopatologi adenokarsinoma prostat.AbstractProstate cancer is the second most common cancer in men around the world. The objective of this study was to determine prognostic factors of prostate adenocarcinoma such as histopathological grading based on the 2005 ISUP modified Gleason system, perineural invasion, and PSA serum. This was a descriptive study of prostate adenocarcinoma diagnosed in Pathology Department from 2010 to 2012. The age and PSA serum level were taken from the medical records. The histological slides were reviewed to confirm Gleason score, and then classified into the histopathological grading. The number of prostate adenocarcinoma cases included in this study was 163. The result shows that the majority of cases were found at 61–70 years old (38.65%), histopathological grading was mostly poorly differentiated (46.63%), positive perineural invasion 22.7% and 83.33% PSA serum above 20 ng/ml. Prostate adenocarcinomas found at age 51-60 years old were mostly well differentiated. On the other hand, cases found at age above 60 years old were mostly poorly differentiated. Perineural invasion was mostly found on poorly differentiated cases. All of histopathological grading showed PSA serum above 20 ng/ml. This study suggested that higher age, perineural invasion and PSA serum level above 20 ng/ml were congruent with the histopathological grading.