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Efficacy Levels of Recombinant Tetravalent Dengue Vaccine (Cyd-Tdv) in Children Aged 2-16 Years: Meta-Analysis Rayhana, Rayhana; Syahniar, Rike; Kharisma, Dayu Swasti; Aron, Belva Elrica; Kamsurya, Rizal
JISIP: Jurnal Ilmu Sosial dan Pendidikan Vol 8, No 3 (2024): JISIP (Jurnal Ilmu Sosial dan Pendidikan) (Juli)
Publisher : Lembaga Penelitian dan Pendidikan (LPP) Mandala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58258/jisip.v8i3.6988

Abstract

Dengue fever is a type of disease with a high and fast transmission rate, especially in tropical and subtropical regions. One of the dengue fever vaccines developed by Sanofi Pasteur (CYD-TDV) and has undergone phase III clinical trials is the tetravalent dengue vaccine. This study aims to conduct a meta-analysis and review analysis of the effectiveness of the dengue vaccine on the level of efficacy at various age levels based on previously published research results. This research uses a quantitative approach through a meta-analysis study. The data in this study were obtained from multiple sources of scientific literature in the form of research articles published in national and international journals. Data was collected online through Google Scholar, PubMed, ProQuest, Cochrane Library, and Scopus—a literature search from various sources using the keyword dengue vaccine. Data analysis was performed with the distinct stages of the study sample, effect size heterogeneity testing, calculating summary effects, calculating p-values, and determining and plotting publication bias/trim-fill analysis. The research results showed that administration of the tetravalent vaccine (CYD-TDV) to children aged 2-16 years had a moderate relationship with a Random Effect value (r ̅_RE)=0.400. The efficacy level of the CYD-TDV dengue vaccine significantly impacts patients who are given the vaccine regularly at certain time intervals (I2=4.46%).
Mengenal Lebih Dekat Dengan Virus Dengue Dan Cara Penanganannya Rayhana, Rayhana; Anadani, Adinta Anadani; Kharisma, Dayu Swasti; Amin, Noor Latifah; Farhan, Fanny Septiani; Suryanda, Faradillah; Nuban, Yohanis
Abdi Masyarakat Vol 4, No 2 (2022): Abdi Masyarakat
Publisher : Lembaga Penelitian dan Pendidikan (LPP) Mandala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58258/abdi.v4i2.4272

Abstract

Dengue virus is a virus transmitted by mosquitoes namely Aedes aegypti. We educate people about dengue virus and how to handle it so that people, especially endemic areas, can better understand the pattern of dengue virus spread which can cause dengue hemorrhagic fever (DHF) as one of the most deadly diseases. If it continues it can lead to shock due to bleeding. DKI Jakarta area, especially East Jakarta, is one of the endemic areas for DHF. As many as 265 cases of dengue hemorrhagic fever (DHF) have occurred in East Jakarta since the beginning of 2020. The community needs to know more about how to prevent DHF through knowledge of lifestyles where the dengue virus reproduces and how it is transmitted. The local community was very enthusiastic about listening to the counseling, as seen from the satisfaction questionnaire, more than 50% answered that they were satisfied with this counseling.
Pencegahan Wabah Penyakit Kaki, Tangan dan Mulut, Cacar monyet, dan Hepatitis Misterius Kharisma, Dayu Swasti; Syahniar, Rike; Rayhana, Rayhana; Latifah, Noor; Ferdiansyah, Ferry; Fauzia, Ghina Zahrotul
Abdi Masyarakat Vol 5, No 1 (2023): Abdi Masyarakat
Publisher : Lembaga Penelitian dan Pendidikan (LPP) Mandala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58258/abdi.v5i1.4627

Abstract

The emergence of various outbreaks in the midst of the ongoing Covid-19 pandemic is quite worrying. Among them are mysterious hepatitis, Hand Mouth and Foot Disease (HMFD), and monkeypox, also known as monkeypox. This is the main reason for the importance of the public to know valid information about infectious diseases and how to prevent them. One of the efforts to increase public knowledge is to conduct counseling and assistance on a regular basis, with the hope of increasing public awareness so as to reduce transmission rates. Counseling was carried out with material on introduction to outbreaks of acute hepatitis, monkeypox and HMFD accompanied by Clean and Healthy Living Behavior for prevention and taught how to wash hands in the right way, and how to wear the mask correctly. 76.4% of respondents were satisfied with this counseling activity. There was an increase in the mean value of the participants knowledge before and after counseling, with the mean + SD pre and post test values respectively 84.4 ± 19.7 and 85 ± 21. There was no statistically difference knowledge before and after counseling with a p-value of 0.728.