Nur Aisiyah Widjaja
Child Health Department, Faculty Of Medicine, Dr Soetomo General Hospital, Surabaya, Indonesia

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The Association of Adiponectin Serum Level and Body Mass Index among Javanese Obese Adolescents Christine Florens; Nur Aisiyah Widjaja; Roedi Irawan; Meta Herdiana Hanindita
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16831

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Association of Adipoq +45 T>G Gene Polymorphism with Insulin Resistance and Icam-1 Value in Obese Adolescents Alexander Leonard Caesar Josediputra; Nur Aisiyah Widjaja; Roedi Irawan
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17444

Abstract

Influence of n-3 Fish Oil-Enriched Intravenous Lipid Emulsion on Length of Stay and Mortality in Infants Post Intestinal Surgery Meta Herdiana Hanindita; Khadijah Rizky Sumitro; Nur Aisiyah Widjaja; Roedi Irawan; Boerhan Hidayat
Health Notions Vol 3, No 3 (2019): March
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn.v3i3.314

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Background: Parenteral nutrition plays an important role in the infants post intestinal surgery. Currently, n-6 soybean oil-based intravenous lipid emulsion (IVLE) is used as a standard. n-6 have been shown increases biomarkers of inflammation while n-3 have shown positively influence clinical outcomes due to their immunomodulatory action. The aim of this study is to investigate the influence of n-3 fish oil-enriched IVLE on mortality and length of stay in infants post intestinal surgery. Methods: A medical record retrospective study was undertaken in infants post intestinal surgery at Dr. Soetomo Hospital in 2016-2017. Infants with intestinal atresia who had PN for at least three days were included. The n-6 soybean oil-based and n-3 fish oil-enriched IVLE were used. Incomplete data was excluded. Results: There were 19 infants (12/19 boys) included in this study. 10/19 infants received the n-6 soybean oil-based IVLE. The duration and dose of IVLE used were 16.52±11.34 days and 1.80±0.44 g/kg/day. Mortality rate was significantly lower in n-3 fish oil-enriched IVLE group (P=0.02) while there was no difference on length of stay (P=0.484).Conclusion: Infants who received the n-3 fish oil-enriched IVLE have a lower mortality rate but there is no difference on length of stay. Keywords: Infants, Intestinal surgery, Intravenous lipid emulsion, Length of stay, Mortality
Usage of Foods for Special Medical Purposes in the Pediatric Ward Dr. Soetomo Hospital Surabaya Dwi Lestari Avianti; Nur Aisiyah Widjaja; Roedi Irawan
Health Notions Vol 4, No 11 (2020): November
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn41101

Abstract

Children who are hospitalized are at risk of malnutrition due to increased energy requirements caused by underlying disease, drug use, decreased appetite and inadequate diet during treatment which can inhibit growth and development. Medical nutrition is required to use food for special medical purposes (FSMP) to meet nutritional needs during hospitalization. The aim of this study is to know the number of patients and types of medical indications for FSMP administration. This research was conducted from August 2018 to October 2018 by reviewing the medical records of children who were treated in the pediatric ward Dr. Soetomo Surabaya. The inclusion criteria were children aged 1 month -18 years and received FSMP as indicated. The sampling method is total sampling. Data in the form of age, gender, nutritional status, disease diagnosis and FSMP type administration, were obtained from medical records from April 2017 to April 2018. The samples obtained were grouped according to indications for FSMP use based on the pediatric drug dosage book of the Indonesian Pediatric Association. A total of 402 children were enrolled in this study. Male patients who received FSMP were 229 (56.9%). The highest use of FSMP was at the age of less than 1 year as many as 195 patients (48.5%) with the highest indication of malnutrition. The most indications for FSMP are malnutrition as many as 267 patients (66.4%), which was caused by gastrointestinal (GI) disease (24.4%), malignancy (18.4%) and congenital heart disease (CHD) (11.2%). The second highest indication of FSMP was malabsorption in 210 patients (52.2%), caused by gastrointestinal disease (41.4%) and cholestasis (17.6%). Another indication that there was volume limitation in 51 patients (12.7%), mostly due to CHD accompanied by heart failure and cow's milk protein allergy (CMPA) in 38 patients (9.5%), more with gastrointestinal symptoms (60.5%) than respiratory symptoms (39.5%). The use of FSMP in the pediatric ward Dr. Soetomo Hospital, Surabaya with medical indications of malnutrition (moderate malnutrition, severe malnutrition, failure to thrive), malabsorption, volume limitation and cow's milk protein allergy with malnutrition as the most indications. Keywords: hospitalized children; medical nutrition; foods for special medical purposes; nutritional requirements
ENERGI, MAKRONUTRIEN, DAN CAROTID INTIMA-MEDIA THICKNESS (CIMT) PADA REMAJA OBESITAS [Energy, Macronutrients, and Carotid Intima-Media Thickness (CIMT) in Obese Adolescents] Nur Aisiyah Widjaja; Roedi Irawan; Meity Ardiana; Meta Herdiana Hanindita; Rendi Aji Prihaningtyas
Media Gizi Indonesia Vol. 15 No. 1 (2020): JURNAL MEDIA GIZI INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v15i1.22-26

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Obesity prevalence is increasing in adolescents. Subclinical chronic infl ammation in obesity causes complication, such as atherosclerosis. Cardiovascular disease is one of the complications of obesity that causes premature death. Carotid intima-media thickness (CIMT) is a subclinical marker of atherosclerosis which easily performed and noninvasive. Early detection of atherosclerosis can improved outcome. Healthy diet have a negative correlation with CIMT meanwhile high calori diet increase CIMT. This study aimed to examine the eff ect of energy and macronutrients intake on CIMT in obese adolescents. A cross sectional study was conducted on 59 adolescents aged 13-16 years old with obesity in pediatric clinic of Dr. Soetomo General Hospital using consecutive sampling method. Dietary intake was obtained through 1 x 24 hours food recall. Anthropometric measurements include body height and weight. Body Mass Index (BMI) was calculated. Obesity is defi ned as BMI higher than 95th percentile based on age and gender (CDC 2000 curve). CIMT examination was performed using B mode ultrasonography on the neck. Statistical analysis was perfomed using mutiple linear regression to analyze the eff ect of total energy, fat, and carbohydrate on CIMT. There were 59 obese adolescents included in this study, consist of 27 (45.8%) female adolescents and 32 (54.2%) male adolescents. No eff ects of total energy, carbohydrate, and fat on CIMT was found in obese adolescents (p>0.05). Further research with more subjects and at least 2x24 hours food recall are needed to assess the eff ect of calories and macronutrients on CIMT in obese adolescents.
EFFECT OF FISH-OIL-ENRICHED INTRAVENOUS LIPID EMULSION ON SYSTEMIC INFLAMMATORY RESPONSE SYNDROME IN POST INTESTINAL SURGERY CHILDREN Khadijah Rizky Sumitro; Meta Herdiana Hanindita; Nur Aisiyah Widjaja; Roedi Irawan
Media Gizi Indonesia Vol. 15 No. 3 (2020): JURNAL MEDIA GIZI INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v15i3.214-218

Abstract

Intravenous lipid emulsions (IVLE) is one of the compositions of the parenteral nutrition (PN) that recommended in children who cannot meet their caloric requirements especially after small intestinal surgery and diff erentiated by their infl ammatory eff ects. The fi rst generation IVLE is proinfl ammatory, the second and the third are infl ammatory neutral, while the fourth (fi sh-oil-enriched) is anti-infl ammatory. The objective of this study is to investigate the eff ect of fi shoil enriched IVLE on systemic infl ammatory response syndrome (SIRS) in children after small intestinal surgery. A retrospective study using medical record was undertaken in children after small intestinal surgery admitted Dr. Soetomo Hospital, Surabaya in 2016-2017. Children with duodenal and jejunoileal atresia who had PN for at least three days were included. The types of IVLE used are FOLE and non-FOLE. Defi nition of SIRS was based on International Pediatric Sepsis Consensus Conference in 2005. A total of 25 children were included in this study. There were 44% children received FOLE and 48% received non-FOLE while 8% children received no IVLE. Median duration and dose of IVLE was 8 (5-15,5) days and 1,8 (1,25-2) g/kg/day. SIRS was signifi cantly more common in girls (OR 9 95%CI 1,3-63,0; p=0,036) and in the non-FOLE children (OR 8,0 95% CI 1,24 – 51,50; p=0,022).
LINGKAR PINGGANG DAN ADIPONEKTIN PADA REMAJA OBESITAS Waist Circumference and Adiponectin in Obese Adolescents Nur Aisiyah Widjaja; Rendi Aji Prihaningtyas; Meta Herdiana Hanindita; Roedi Irawan
Media Gizi Indonesia Vol. 15 No. 2 (2020): JURNAL MEDIA GIZI INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v15i2.88-93

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Obesity causes low-grade chronic infl ammation. Adiponectin is an anti-infl ammatory cytokine. Increased waist circumference in obesity infl uences pro-infl ammatory and anti-infl ammatory cytokine levels which increase the risk of metabolic complications. This study was a cross-sectional study conducted at the Nutrition and Metabolic Diseases Clinic of Children's Hospital Dr. Soetomo, Surabaya. Subjects were chosen consecutively as many as 59 obese adolescents with inclusion criteria: obesity, aged 13-16 years, and having parents / guardians who were willing to follow the research and exclusion criteria: taking drugs, such as dyslipidemia, getting hormone therapy, suff ering from secondary obesity , suff ers from endocrine abnormalities, and has an infection or infl ammatory disease. Anthropometric examination was performed on subjects, including body weight, height, and waist circumference. Body Mass Index (BMI) is measured by weight calculation (kg) divided by height squared (meters) and plotted into the CDC 2000 curve. Obesity is established if a Body Mass Index/Age (BMI/A) >P95 is obtained according to age and sex on the CDC 2000 curve. Adiponectin levels are examined using venous serum with ELISA. The relationship between waist circumference and adiponectin levels was analyzed by Pearson correlation. 59 subjects were included in this study. The mean of waist circumference and adiponectin were 100.18 ± 10.63 cm and 7,84 ± 3,81 μg / ml. Statistic test showed that there is no correlation between waist circumference and adiponectin levels in obese adolescents (p>0,05). There is no correlation between waist circumference and adiponectin levels in obese adolescents. Factors that aff ect the correlation between waist circumference and adiponectin include race, diet and physical activity
SLEEP DURATION AND METABOLIC SYNDROME IN OBESE ADOLESCENTS Nur Aisiyah Widjaja; Rendi Aji Prihaningtyas; Roedi Irawan; Meta Herdiana Hanindita
Media Gizi Indonesia Vol. 16 No. 1 (2021): JURNAL MEDIA GIZI INDONESIA (National Nutrition Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v16i1.33-37

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Shorter sleep duration is a risk factor for obesity and metabolic syndrome. Previous studies conducted on diff erent races showed inconsistent results. The purpose of this study was to analyze the diff erences in sleep duration in obese adolescents who suff er from metabolic syndrome compared with obese adolescents who do not suff er from metabolic syndrome. A cross sectional study was carried out on 59 obese adolescents who visited the Pediatric Nutrition and Metabolic Disease Clinic in Dr. Soetomo General Academic Hospital, Surabaya. Subjects were selected using total sampling techniques who met the inclusion and exclusion criteria in August-November 2018. Anthropometry (weight, height and waist circumference), blood pressure, and blood tests (HDL cholesterol levels, triglycerides, and fasting blood glucose levels) were held to determine obesity according to CDC 2000 and metabolic syndrome according to International Diabetes Federation. The diff erence in sleep duration in obese adolescents suff ering from metabolic syndrome and without metabolic syndrome analyzed using Chi square test. A total of 27 subjects (45.8%) suff ered from metabolic syndrome. Most obese adolescents (57,6%) have suffi cient sleep duration (≥ 8 hours/day). There was no sleep duration diff erences in obese adolescents suff ering and not suff ering from metabolic syndrome (p> 0.05).
THE COMPOSITION OF CARBOHYDRATE AND FAT CONSUMPTION AMONG OBESE ADOLESCENTS IN SURABAYA AND SIDOARJO Christine Florens; Nur Aisiyah Widjaja; Roedi Irawan; Meta Herdiana Hanindita
Media Gizi Indonesia Vol. 17 No. 1 (2022): JURNAL MEDIA GIZI INDONESIA (NATIONAL NUTRITION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v17i1.62-69

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Carbohydrates and fats are macronutrients that have been the most influential factors to obesity. The excess of consumed carbohydrates or fats will be stored as triglycerides in adipocytes. This study aims to analyze the proportion of carbohydrates and fats consumption among obese adolescents from Surabaya and Sidoarjo. This study also revealed the relationship between the proportion with the total calories consumption and body mass index (BMI). This cross-sectional study involved obese adolescents aged 13-18 years old from several junior and senior high schools, conducted during May-September 2020. The subject was selected using a total population sampling method that met inclusion and exclusion criteria. Anthropometries (weight and height) were measured to calculate BMI and determine obesity according to CDC 2000 criteria. A 24-hour-food-recall for the last two days was used to get the dietary information. This study divided carbohydrates consumption into three groups (high (HC), moderate (MC), low(LC)) and fats consumption into two groups (high fats (HF) and non-high fats (Non-HF)). There were 240 obese adolescents participating in this study; 40.4% of them consuming high carbohydrates and 17.5% of them consuming HF on their diets. Although there were several distinctions in carbohydrates and fats composition on diet, the total calorie and the mean BMI were not considerably different based on macronutrients consumption. In conclusion, there were two types of imbalance proportion of macronutrients consumption among our participants, high–carbohydrates-low-fats diet and low-carbohydrates-high-fats-diet.