Klarin, Felicia
Unknown Affiliation

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

COMPARISON OF MORTALITY BETWEEN THE COMBINATION OF STANDARD THERAPY AND CONVALESCENT PLASMA THERAPY AND STANDARD THERAPY ONLY IN COVID-19 PATIENTS : SYSTEMATIC REVIEW AND META-ANALYSIS Klarin, Felicia; Vita, Angelica Diana; Siahaan, Cynthia Elvira Sari; Rifdah, Salsabila Nabilah; Putri, Ayu Rahmanita; Kusuma, Indriasti Putri; Prayitno, Subur
Journal of Community Medicine and Public Health Research Vol. 2 No. 2 (2021): Journal of Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (431.579 KB) | DOI: 10.20473/jcmphr.v2i2.27432

Abstract

Coronavirus Disease-19 (COVID-19) is an infectious disease caused by a newly discovered type of coronavirus. Comprehensive management for COVID-19 patients includes infection control, hemodynamic stability maintenance, oxygenation monitoring, ventilation, and pharmacotherapy administration. Convalescent plasma is one of the COVID-19 therapy choices, proven to provide relief for Ebola, SARS, and MERS patients. Therefore, the authors believed in searching data on whether convalescent plasma therapy also improves COVID-19 patients, specifically in terms of mortality. This study aims to compare the comparison in mortality between standard therapy and convalescent plasma therapy with standard therapy only in COVID-19 patients. This study used a systematic review and meta-analysis method according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. This study used ten studies that met the inclusion criteria to evaluate the comparison in mortality between the combination therapy with standard therapy only in COVID-19 patients. There was a significant difference in mortality between the combination of standard therapy and convalescent plasma therapy with standard therapy only in COVID-19 patients, and mortality in the combination therapy groups being lower than standard therapy only.