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All Journal Medali Jurnal : Media Dental Intelektual ODONTO Dental Journal Jurnal Kedokteran Gigi Universitas Padjadjaran Jurnal Material Kedokteran Gigi Jurnal Kedokteran Gigi Terpadu Jurnal Abdimas Kesehatan Terpadu Odonto dental journal
Taufiq Ariwibowo
Departemen Konservasi Gigi, Fakultas Kedokteran Gigi, Universitas Trisakti, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Journal : ODONTO Dental Journal

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Potential Natural Antibacterial Agent for P. gingivalis Periodontitis Infection: A Comprehensive Review of Source, Structure and Mechanism actions Meiny Faudah Amin; Taufiq Ariwibowo; Salsabila Aqila Putri; Dikdik Kurnia
Odonto : Dental Journal Vol 11, No 1 (2024): July 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.1.146-158

Abstract

The pathogenic bacteria P. gingivalis grows in the oral cavity. This bacterium could attack immune system which lead to inflammation of most tissues. P. gingivalis can cause a variety of serious and dangerous condition such as periodontitis, Alzheimer, rheumatoid arthritis, diabetes, and pneumonia. Antibiotics have been used for years as a treatment against this bacterium, like metronidazole, amoxicillin, and clindamycin, however, P. gingivalis is reported to be resistant to these antibiotics, thus exploration to discover alternatives has been demanded. Natural product compounds are known to have antibacterial activity and cause fewer side effects. Turmeric, eucalyptus, and several other plants have been reported to have antibacterial activity against P. gingivalis with a MIC of 1g/mL from an ethyl acetate leaf extract of eucalyptus. Decent antibacterial activity could be used as a reference to discover new drugs as alternatives against P. gingivalis
Co-Authors Aditya Pratama Sarwono Alyssa Devina Amalia Andy Wirahadikusumah Bernard O. Iskandar Bryan Wangidjaja Chandra Dwidjayanti, Siti Dewi Priandini Didi Nugroho Dikdik Kurnia Dikdik Kurnia F Loes Djimahit Sjahruddin Faaudah Amin, Meiny Febria Febria Johan Arief Budiman Jonathan Morgan Sudjaka Juanita Amaludin Gunawan Juanita Amaludin Gunawan Lestari Sri Meiny Faudah Amin Mutiara Risa Anggriani Niko Falatehan Putri Nur Pratiwi Putri, Salsabila Aqila Ratih Nur Baiti Salsabila Aqila Putri Siti Rofilah Sandaeng Sri Ratna Laksmiastuti Stella Fibriyanti Bahry Sucanto, Felicia Tien Suwartini Wirahadikusumah Andy Yohana Yusra