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Journal : Homeostasis: Jurnal Mahasiswa Pendidikan Dokter

PERBEDAAN KADAR FERITIN PADA IBU HAMIL DENGAN COVID-19 TANPA DAN DISERTAI PREEKLAMPSIA Penelitian di RSUD Ulin Banjarmasin Periode Maret 2020- Periode Maret 2020-Februari 2022 Rahmatullah, Muhammad Ikhsan; Armanza, Ferry; Hendriyono, Fransiskus Xaverius; Aditya, Renny; Rahmiati, Rahmiati
Homeostasis Vol 6, No 3 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i3.11459

Abstract

COVID-19 is an infectious disease which become a pandemic worldwide. Pregnant women are a vulnerable group infected with COVID-19. Ferritin is a marker of increased inflammation associated with the severity of COVID-19. Pregnant women with COVID-19 have a higher mortality than pregnant women without COVID-19. Low ferritin levels during 28-30 weeks of gestation are associated with a low incidence of preeclampsia. This study aims to determine whether there are significant feritin level difference in pregnant women with COVID-19 without and with preeclampsia. This type of research is analytic observational using a cross-sectional study design with retrospective data collection. The results of the study obtained 603 subjects, but only 63 subjects met the inclusion criteria. Pregnant women with COVID-19 without preeclampsia as 36 subjects were randomized thus obtained 27 subjects were pregnant women with COVID-19 without preeclampsia and 27 subjects were pregnant women with COVID-19 accompanied by preeclampsia. Pregnant women with COVID-19 without preeclampsia had a median 66 ng/mL with a minimum value 1 ng/mL and a maximum value 951 ng/mL and pregnant women with COVID-19 accompanied by preeclampsia had a median 55 ng/mL with a minimum value 2 ng/mL and a maximum value 1.112 ng/mL. The conclusion of this study was that there was no significant feritin level difference in pregnant women with COVID-19 without and with preeclampsia with p=0.924.
PERBEDAAN RASIO NEUTROFIL-LIMFOSIT DAN C-REACTIVE PROTEIN PADA IBU HAMIL DENGAN COVID-19 TANPA DAN DISERTAI PREEKLAMPSIA Penelitian di RSUD Ulin Banjarmasin Periode Maret 2020 - Periode Maret 2020-Februari 2022 Qaedi, Muhammad Bari Nur; Armanza, Ferry; Hendriyono, Fransiskus Xaverius; Aditya, Renny; Rahmiati, Rahmiati
Homeostasis Vol 6, No 3 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i3.11456

Abstract

COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. Pregnant women are vulnerable to COVID-19. Preeclampsia is a complication in pregnant women characterized by hypertension at > 20 weeks of gestation and proteinuria. The Neutrophils Lymphocyte Ratio and C-Reactive Protein is a marker of inflammation related to disease severity. Elevated NLR and CRP are associated with COVID-19 and preeclampsia. The study aims to determine whether there are significant differences in NLR values or CRP levels for pregnant women with COVID-19 without and with preeclampsia. This type of research is analytic observational using a retrospective cross-sectional study. The results of the study were 603 subjects, 70 subjects met the inclusion criteria. Subjects of pregnant women with COVID-19 without preeclampsia were randomized, obtained 30 subjects of pregnant women with COVID-19 without preeclampsia and 30 subjects accompanied by preeclampsia. The NLR value of pregnant women with COVID-19 without preeclampsia had a median of 5.57, a minimum value of 1.90 and a maximum value of 30.38. Those accompanied by preeclampsia had a median of 5.13, a minimum value of 2.04 and a maximum value of 18.10. CRP levels of pregnant women with COVID-19 without preeclampsia had a median of 45.2 mg/L, a minimum value of 2.0 mg/L and a maximum value of 240.0 mg/L. Those accompanied by preeclampsia had a median of 50.4 mg/L, a minimum value of 2.6 mg/L and a maximum value of 318.1 mg/L. Conclusion: there was no significant difference in NLR values or CRP levels in pregnant women with COVID-19 without and with preeclampsia (p=0.631, p=0.478).