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Sinaga, Harida Panduwita
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Health Professions Medicine & Pharmacology Public Health

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Peningkatan Tekanan Intraokular pada Sindrom Nefrotik Sinaga, Harida Panduwita; -, Rusdidjas; Ramayati, Rafita; Rina Ramayani, Oke; Siregar, Rosmayanti; Siregar, Beatrix
Cermin Dunia Kedokteran Vol 45, No 8 (2018): Alopesia
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (92.867 KB) | DOI: 10.55175/cdk.v45i8.626

Abstract

Sindrom nefrotik (SN) merupakan penyakit ginjal terbanyak pada anak. Tatalaksana medikamantosa utama SN adalah menggunakan kortikosteroid; penggunaan dosis tinggi dan jangka lama dapat memiliki efek samping, salah satunya peningkatan tekanan intraokular. Mekanisme pasti peningkatan tekanan intraokular diinduksi steroid belum diketahui pasti, steroid dapat meningkatkan resistensi pengeluaran aqueous humor.Nephrotic syndrome (NS) is the most common kidney disease in children. Corticosteroid is still preferred as primary treatment. High-dose and long term use of corticosteroids can increase intraocular pressure. The mechanism of steroid-induced increased intraocular pressure is not clearly understood; steroids can increase aqueous humor outflow resistance.
Co-Authors Beatrix Siregar, Beatrix Oke Rina Ramayani, Oke Rina Rafita Ramayati, Rafita Rosmayanti Siregar, Rosmayanti Rusdidjas -, Rusdidjas