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All Journal Althea Medical Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Proceeding of the Electrical Engineering Computer Science and Informatics Proceeding of the Electrical Engineering Computer Science and Informatics Media Medika Muda Ophthalmologica Indonesiana
Elsa Gustianty
Departemen Ilmu Kesehatan Mata, Universitas Padjadjaran
Biochemistry, Genetics & Molecular Biology Computer Science & IT Electrical & Electronics Engineering Health Professions Medicine & Pharmacology Neuroscience Physics Public Health

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Pseudoexfoliation Glaucoma in the National Eye Center, Cicendo Eye Hospital, January–October 2012 Ramdhani, Rizki Fasa; Gustianty, Elsa; Dwiyatnaningrum, Fenny
Althea Medical Journal Vol 2, No 1 (2015)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (669.525 KB)

Abstract

  Background: Pseudoexfoliation syndrome is characterized by the deposition of a distinctive fibrillar material in the anterior segment of the eye. This condition is a major risk factor for development of glaucoma, termed pseudoexfoliation glaucoma (PEXG). The aim of this study was to describe the characteristic and management of PEXG in the National Eye Center Cicendo Eye Hospital.Methods: A descriptive retrospective study was conducted in October–November 2012 using medical records of PEXG patients in the National Eye Center Cicendo Eye Hospital during January–October 2012. Results: There were 32 patients (43 eyes) diagnosed as PEXG, most of them were male (78.1%), age 70–74 years old (34.4%) and followed by those in the range of age 65–69 years old (21.9%). Most of the cases were unilateral (65.6%) decrease of visual acuity less than 3/60 (76.7%), increase of intraocular pressure (IOP) with majority in the range of 31–40 mmHg (32.6%) and 41–50 mmHg (32.6%), Cup/Disc Ratio 0.9–1.0 (46.51%) and followed by those classified as majority which were hard to assess because of the presence of opaque media (34.89%). The type of glaucoma was open angle glaucoma (88.4%). The treatment received was a combination of two types of antiglaucoma medication and surgery IOPConclusion: PEXG is mostly found in elderly patients. While most of the patients come with high IOP and late stage of the disease IOPKeywords: Characteristics, glaucoma, pseudoexfoliation DOI: 10.15850/amj.v2n1.446 
One Year Data of New Secondary Glaucoma Patients at Top Referral Eye Hospital in Indonesia Rifqah, Elka; Gustianty, Elsa; Prajitno, Ihrul Prianza
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.944 KB) | DOI: 10.15850/amj.v4n2.1060

Abstract

Background: Glaucoma is the second most common cause of blindness after cataract in the world and also in Indonesia. Based on the etiology, glaucoma is classified into primary and secondary glaucoma. Secondary glaucoma can cause severe visual function disorders and affect the patient’s quality of life. This study was carried out to indentify the characteristics of new secondary glaucoma patients at Cicendo Eye Hospital from January to December 2013. Methods: This descriptive study was carried out at Cicendo Eye Hospital from November to December 2014. Secondary data were retrieved from medical records of new secondary glaucoma patients who came to the Glaucoma unit from January to December 2013. Inclusion criteria were medical records comprising data about age, gender, location of the affected eyes by secondary glaucoma, etiology of secondary glaucoma and value of intraocular pressure. The collected data were recorded and analyzed to  illustrate their frequency distribution and proportion.Results: Out of 63 patients, 42.9% was 40–59 years old and 63.5% was men. Most cases were unilateral (82.5%). It was found that 74 eyes (52 unilateral, 11 bilateral), diagnosed as secondary glaucoma, had intraocular pressure ≥30 mmHg which were 54.1%. Secondary glaucoma were caused by lens induced (36.5%), inflammation (22.2%), and trauma (9.5%).Conclusions: Most cases are middle-aged patients and dominated by men. The eye diagnosed as secondary glaucoma occurred more in the unilateral eye which has intraocular pressure ≥30 mmHg and is caused by lens induced and inflammation. DOI: 10.15850/amj.v4n2.1060
Automated Post-Trabeculectomy Bleb Assesment by Using Image Processing Fahanani, Agwin Fahmi; Zakaria, Hasballah; Prahasta, Andika; Gustianty, Elsa; Rifada, R. Maula; Chairini, Astrid
Proceeding of the Electrical Engineering Computer Science and Informatics Vol 4: EECSI 2017
Publisher : IAES Indonesia Section

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (660.332 KB) | DOI: 10.11591/eecsi.v4.1002

Abstract

Glaucoma is a second leading cause of blindness after cataract. Glaucoma caused by unbalance absorption of aqueus humour so it increase intraocular pressure. As a result, it surpresses nerve cells so that nerve cells can not get enough blood flow as nutrition intake and can lead to permanent blindness. One of the treatment for glaucoma is by surgical procedure, called trabeculectomy. After the surgery a slightly lifted tissue due to passing fluid, called bleb, should appears. Bleb assesment is necessary to examine the successful of trabeculectomy surgery. One of standard assesment is Indiana Bleb Appearance Grading Scale (IBAGS). Ophthalmologist used this standard to grade the bleb images manually so the result is subjective. This work offered a new approach to standardize the system of bleb assessment by computer software. Features related to bleb height, width and vascularity were extracted from the bleb image by using image processing algorithm. The KNN algorithm then used to classify the image according the IBAGS. The proposed method has successfully increased the Cohen’s kappa coefficient from 0.56 to 0.63. Therefore, it potentially reduced the subjectivity of the bleb grading.
One Year Data of New Secondary Glaucoma Patients at Top Referral Eye Hospital in Indonesia Elka Rifqah; Elsa Gustianty; Ihrul Prianza Prajitno
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.944 KB) | DOI: 10.15850/amj.v4n2.1060

Abstract

Background: Glaucoma is the second most common cause of blindness after cataract in the world and also in Indonesia. Based on the etiology, glaucoma is classified into primary and secondary glaucoma. Secondary glaucoma can cause severe visual function disorders and affect the patient’s quality of life. This study was carried out to indentify the characteristics of new secondary glaucoma patients at Cicendo Eye Hospital from January to December 2013. Methods: This descriptive study was carried out at Cicendo Eye Hospital from November to December 2014. Secondary data were retrieved from medical records of new secondary glaucoma patients who came to the Glaucoma unit from January to December 2013. Inclusion criteria were medical records comprising data about age, gender, location of the affected eyes by secondary glaucoma, etiology of secondary glaucoma and value of intraocular pressure. The collected data were recorded and analyzed to  illustrate their frequency distribution and proportion.Results: Out of 63 patients, 42.9% was 40–59 years old and 63.5% was men. Most cases were unilateral (82.5%). It was found that 74 eyes (52 unilateral, 11 bilateral), diagnosed as secondary glaucoma, had intraocular pressure ≥30 mmHg which were 54.1%. Secondary glaucoma were caused by lens induced (36.5%), inflammation (22.2%), and trauma (9.5%).Conclusions: Most cases are middle-aged patients and dominated by men. The eye diagnosed as secondary glaucoma occurred more in the unilateral eye which has intraocular pressure ≥30 mmHg and is caused by lens induced and inflammation. DOI: 10.15850/amj.v4n2.1060
Pseudoexfoliation Glaucoma in the National Eye Center, Cicendo Eye Hospital, January–October 2012 Rizki Fasa Ramdhani; Elsa Gustianty; Fenny Dwiyatnaningrum
Althea Medical Journal Vol 2, No 1 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (669.525 KB)

Abstract

  Background: Pseudoexfoliation syndrome is characterized by the deposition of a distinctive fibrillar material in the anterior segment of the eye. This condition is a major risk factor for development of glaucoma, termed pseudoexfoliation glaucoma (PEXG). The aim of this study was to describe the characteristic and management of PEXG in the National Eye Center Cicendo Eye Hospital.Methods: A descriptive retrospective study was conducted in October–November 2012 using medical records of PEXG patients in the National Eye Center Cicendo Eye Hospital during January–October 2012. Results: There were 32 patients (43 eyes) diagnosed as PEXG, most of them were male (78.1%), age 70–74 years old (34.4%) and followed by those in the range of age 65–69 years old (21.9%). Most of the cases were unilateral (65.6%) decrease of visual acuity less than 3/60 (76.7%), increase of intraocular pressure (IOP) with majority in the range of 31–40 mmHg (32.6%) and 41–50 mmHg (32.6%), Cup/Disc Ratio 0.9–1.0 (46.51%) and followed by those classified as majority which were hard to assess because of the presence of opaque media (34.89%). The type of glaucoma was open angle glaucoma (88.4%). The treatment received was a combination of two types of antiglaucoma medication and surgery IOPConclusion: PEXG is mostly found in elderly patients. While most of the patients come with high IOP and late stage of the disease IOPKeywords: Characteristics, glaucoma, pseudoexfoliation DOI: 10.15850/amj.v2n1.446 
Automated Post-Trabeculectomy Bleb Assesment by Using Image Processing Agwin Fahmi Fahanani; Hasballah Zakaria; Andika Prahasta; Elsa Gustianty; R. Maula Rifada; Astrid Chairini
Proceeding of the Electrical Engineering Computer Science and Informatics Vol 4: EECSI 2017
Publisher : IAES Indonesia Section

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (660.332 KB) | DOI: 10.11591/eecsi.v4.1002

Abstract

Glaucoma is a second leading cause of blindness after cataract. Glaucoma caused by unbalance absorption of aqueus humour so it increase intraocular pressure. As a result, it surpresses nerve cells so that nerve cells can not get enough blood flow as nutrition intake and can lead to permanent blindness. One of the treatment for glaucoma is by surgical procedure, called trabeculectomy. After the surgery a slightly lifted tissue due to passing fluid, called bleb, should appears. Bleb assesment is necessary to examine the successful of trabeculectomy surgery. One of standard assesment is Indiana Bleb Appearance Grading Scale (IBAGS). Ophthalmologist used this standard to grade the bleb images manually so the result is subjective. This work offered a new approach to standardize the system of bleb assessment by computer software. Features related to bleb height, width and vascularity were extracted from the bleb image by using image processing algorithm. The KNN algorithm then used to classify the image according the IBAGS. The proposed method has successfully increased the Cohen’s kappa coefficient from 0.56 to 0.63. Therefore, it potentially reduced the subjectivity of the bleb grading.
TRABEKULEKTOMI PADA GLAUKOMA SEKUNDER PASCA VITREKTOMI PARS PLANA DENGAN SILICONE OIL INTRAVITREAL Maharani Maharani; Andika Prahasta; Elsa Gustianty
Media Medika Muda Vol 1, No 1 (2016)
Publisher : Faculty of Medicine Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar belakang: untuk mengetahui keberhasilan operasi trabekulektomi pada glaukoma sekunder pasca vitrektomi pars plana dengan silicone oil intravitrealMetode: data dari 7 pasien dengan glaukoma sekunder pasca vitrektomi pars plana dengan silicone oil intravitreal yang telah dilakukan pengambilan silicone oil dan trabekulektomi dengan atau tanpa mitomicin C di rumah sakit Cicendo dari Januari 2009 sampai dengan Februari 2011. Tekanan intraokuler (TIO) sebelum operasi, 1 hari, 1minggu, 1 bulan dan 2 bulan pasca operasi dicatat dan dianalisis. Hasil: empat (57,14%) dari 7 pasien berusia diatas 45 tahun, dengan rata-rata usia 46,14 tahun (rentang usia 29–63). Semua pasien laki- laki. Lima (71,43%) subjek afakia. Onset glaucoma sekunder rata-rata 78 hari (rentang waktu 2–270). rata rata TIO 1 hari pasca bedah 7,86 mmHg , 1 minggu pasca bedah 25,83 mmHg , 1 bulan pasca bedah 17,50 mmHg, 2 bulan pasca bedah 16,33 mmHg. Satu pasien mengalami keberhasilan tanpa pemberian antiglaukoma topikal pasca bedah, 3 pasien mengalami keberhasilan namun dengan penambahan antiglaukoma topikal pasca bedah dan 2 pasien mengalami kegagalan dan 1 penderita tidak diperoleh data TIO setelah 1 hari pasca bedah. Enam subjek (85,71%) terdapat silicone oil di bilik mata depan, empat diantaranya telah terjadi emulsifikasi, 57,1% mengalami keberhasilan penurunan TIO dan 28,4% mengalami kegagalan. Lima subjek dilakukan trbekulektomi dengan MMC dan empat (57,1%) diantaranya mengalami keberhasilan (p=0,427).Simpulan: usia, status lensa, adanya silicone oil di bilik mata depan dan penggunaan antifibrotik tidak mempengaruhi keberhasilan operasi trabekulektomi pada glaukoma sekunder pasca vitrektomi pars plana dengan silicone oil intravitrealKata kunci: Trabekulektomi, glaucoma sekunder, silicone oli, tekanan intraokuler
Comparison of Ocular Surface Cytological Appearance in Glaucoma Patient Treated with Timolol Maleat 0,5% Latanoprost 0,005% and Timolol-Latanoprost Fixed Combination Preservative Free Eye Drop Maretha Amrayni; Elsa Gustianty; Susi Heryati; Andika Prahasta; Maula Rifada; Hasrayati Agustina
Majalah Oftalmologi Indonesia Vol 44 No 2 (2018): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (203.25 KB) | DOI: 10.35749/journal.v44i2.167

Abstract

Introduction : The longterm use of topical antiglaucoma might cause ocular surface instability due to active substance or preservative used. Impression cytology examination may reveal superficial epithelial cells on conjunctiva and cornea, including goblet cells. Goblet cell density decrease is the most important parameter on evaluation of ocular surface disorder. Objective : This study was to understand ocular surface remodeling due to active substance of topical antiglaucoma with impression cytology examination among the patient prior and 3 months after therapy. Methods : This was a randomized controlled trial study with single blind masking. A total of 45 eyes from 31 patients were used as subject and distributed onto three groups treatment, which were timolol maleat 0.5%, latanoprost 0.005%, and latanoprost-timolol maleat fixed combination. All topical antiglaucoma in this study were preservative free. Result : There were differences between 3 groups in goblet cells density after 3 months therapy (p=0,030). Goblet cell density in timolol group was lower than latanoprost (p=0,041) and fixed combination (p=0,045). There was no significantly difference between 3 groups in conjunctival epithelial metaplasia degree (p=0,706) and cell to cell contact degree in corneal epithelial cells (p=0.66) after 3 months therapy. Conjunctival epithelial metaplasia degree were increased among group of timolol (p=0,008) and fixed combination (p=0,046). Conclusion : Timolol maleat 0,5% caused lower goblet cell density after 3 months therapy compare with latanoprost and fixed combination. There was no significantly difference in conjunctival epithelial metaplasia and cell to cell contact degree in corneal epithelial cells among these glaucoma treatment groups.
Penatalaksanaan Tube Exposed Glaukoma Implant pada Glaukoma Sudut Terbuka Anisa Feby Arifani; Andika Prahasta; Elsa Gustianty; R. Maula Rifada; Sonie Umbara
Majalah Oftalmologi Indonesia Vol 46 No 2 (2020): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (245.932 KB) | DOI: 10.35749/journal.v46i2.100086

Abstract

Pendahuluan : Glaukoma sudut terbuka primer saat ini masih merupakan kasus utama yang menyebabkan morbiditas okular di negara berkembang. Glaucoma drainage device (GDD) merupakan salah satu penatalaksanaan operasi dalam menangani kasus glaukoma. Tindakan operasi GDD memiliki faktor resiko. Erosi pada implant di konjungtiva dan tube exposed merupakan komplikasi paling sering dalam tindakan operasi GDD. Tujuan : Untuk melaporkan kasus penatalaksanaan tube exposed glaukoma implant Presentasi Kasus : Seorang pria, 50 thn datang dengan keluhan tidak nyaman pada mata kanan. Pasien memiliki riwayat operasi glaukoma implant pada mata kanan 5 tahun yang lalu. Pada pemeriksaan opftalmologis mata kanan didapatkan tube exposed disertai dengan injeksi siliar. Pasien kemudian dilakukan penatalaksanaan untuk memperbaiki glaukoma implant dengan menggunakan graft sklera pada mata kanan. Kesimpulan : Tindakan operasi GDD menjadi salah satu tindakan yang biasa dilakukan untuk penatalaksanaan glaukoma , Tube exposed pada GDD dapat di tatalaksana dengan menggunakan graft sklera.
Management of Uveitic Glaucoma in Children with Blau syndrome Ivone Caroline; Elsa Gustianty; Andika Prahasta; R. Maula Rifada
Majalah Oftalmologi Indonesia Vol 48 No 1 (2022): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v48i1.100196

Abstract

Introduction: Glaucoma in children is a condition that potentially cause blindness. Management of uveitic glaucoma is challenging because of the many mechanisms involved in its pathogenesis Purpose: To report clinical characteristic and management of uveitic glaucoma in children with Blau Syndrome. Methods: A 13 years old boy came to the hospital with chief complain blurred vision in both eyes. The patient was diagnosed as Blau Syndrome one year ago. He had history of trabeculectomy on his left eye. Scalling skin and swollen joints was found on physical examination. Visual acuity was hand movement in both eyes, intraocular pressure was 34 (right) and 40 (left). Gonioscopy of the right eye was schwabe line in superior and peripheral anterior synechia in three quadrants. At the left eye, there was scleral spur in all quadrant. At the anterior segment of right eye, there was band keratopathy, posterior synechia 360 o , peripheral anterior synechia, and cataract. While at the left eye, there was bleb, band keratopathy, posterior synechia, peripheral iridotomy, and cataract. Trabeculectomy, 5 fluorouracil, synechiolysis, iris retractor, and membranectomy was performed for the right eye. Conclusion: Uveitic glaucoma in children poses a significant risk of blindness and needs an aggressive treatment to control intraocular pressure and amblyopia therapy to preserve vision.
Co-Authors Agwin Fahmi Fahanani Andika Prahasta Anisa Feby Arifani Astrid Chairini Bachrul Ichsan Mahendra Chairini, Astrid Elka Rifqah Fahanani, Agwin Fahmi Fenny Dwiyatnaningrum Fenny Dwiyatnaningrum, Fenny Hasballah Zakaria Hasrayati Agustina Ihrul Prianza Prajitno Ihrul Prianza Prajitno Ivone Caroline Madona Debora Maharani Maharani Maretha Amrayni Maula Rifada Maulida Rifada R. Maula Rifada R. Maula Rifada R. Maula Rifada Raden Maula Rifada Rifada, R. Maula Rifqah, Elka Rizki Fasa Ramdhani Rizki Fasa Ramdhani, Rizki Fasa Sonie Umbara Susi Heryati Zakaria, Hasballah