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All Journal World Chemical Engineering Journal YASIN: Jurnal Pendidikan dan Sosial Budaya
Hidayati, Anisa
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Chemical Engineering, Chemistry & Bioengineering Social Sciences Other

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Analisis Problematika pada Keterampilan Menulis Permulaan Siswa Kelas II Sekolah Dasar Hidayati, Anisa; Fitriani, Desnita; Aprilia, Rara Nasywa; Fauziah, Sobrini
YASIN Vol 3 No 6 (2023): DESEMBER
Publisher : Lembaga Yasin AlSys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/yasin.v3i6.1626

Abstract

Early writing skills are a critical aspect in a child's language development. This article provides an overview of early writing skills and identifies several challenges often encountered in developing writing abilities among children. The importance of early writing skills as the foundation for language learning and communication is the main focus. This stage involves introducing letter forms, fine motor training, and the ability to connect simple letters into meaningful words. Proficient writing skills serve as the basis for more complex language abilities in the future. However, there are several challenges faced in developing early writing skills in children. One of them is the lack of attention from parents and educators regarding the importance of these writing skills. Insufficient support and appropriate stimulation during the initial learning stage can hinder a child's writing development. Additionally, another challenge is the difficulty experienced by some children in overcoming fine motor obstacles. Their untrained hand-eye coordination makes it challenging to form letters clearly and neatly.
In Silico Study and Bioactivity of Flavonoid Extract Syzygium polyanthum (Wight) Walp. Leaves Against Salmonella typhi Rochmat, Agus; Hidayati, Anisa; Mujijah, Mujijah; suhaedah, suhaedah
World Chemical Engineering Journal VOLUME 4 NO. 2 DECEMBER 2020
Publisher : Chemical Engineering Department, Engineering Faculty, Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/wcej.v4i2.10593

Abstract

Salmonella typhi bacteria cause complications of bleeding in the intestine or intestinal perforation. However, Salmonella typhi bacteria will become resistant to chloramphenicol due to the formation of plasmids that produce the chloramphenicol acetyl transferase (CAT) enzyme which works to activate chloramphenicol. So, the search for active groups of natural compounds which are expected to have the work of deactivating the CAT enzyme. One of them is a flavonoid compound. The flavonoid group is widely used as an antimicrobial. This research was aimed at the extraction of bay leaf flavonoids. The presence of flavonoids was proven by phytochemical tests, namely a yellow color change with a slightly acidic amyl alcohol solvent - Mg metal and strengthened by the scanning results of the maximum wavelength on the band 1 407 nm and band 2 338 nm which is a special feature of flavonoid backbone. The results of GC-MS analysis obtained 4 flavonoid compounds from bay leaf extract which have an abundance above 1% and qualification above 90%: 2,3-Dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one, alpha- tocopherol, beta-tocopherol, and pyragallol. The correlation between the results of the inhibitory test against Salmonella typhi at a concentration of 100 ppm with the results of docking tocopherol - 3CLA receptors which have an affinity bond energy / ∆Gbinding = 7.40 kcal / mol, indicates that the bay leaf flavonoid extract can inhibit the formation of chloramphenicol acetyl transferase (CAT).
Co-Authors Aprilia, Rara Nasywa Fauziah, Sobrini Fitriani, Desnita Mujijah, Mujijah Rochmat, Agus Suhaedah Suhaedah, Suhaedah