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Quantitative Risk Assesment of Benzene Exposure in Printing Industry X Surabaya City Amanda Fithri Habibati; Abdul Rohim Tualeka; Juliana Jalaludin; Syamsiar Russeng; Ahsan; Puji Rahmawati
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17453

Abstract

Benzene is a compound chemically volatile and lasts a long time in the air and quicklyinhaled into the human body. The use of benzene is widely used in various industries, one ofwhich is the printing industry. Benzene produced right in the printing industry are ink, cleaning fluid,and when the machine in operation. Workers exposed to benzene can risk cancer and non-cancer healtheffects that are harmful to the human body. This study aimed to assess cancer and non-cancer risk ofworkers in the printing industry X Surabaya City. This research is observational, cross-sectional withthe same sample with a total population of 11 workers in the printing industry X Surabaya City. Therisk assessment method uses four stages: hazard identification, exposure analysis, dose and responseanalysis, and risk characterization. This research shows that the average concentration of benzene is1.0729 mg/m3 or 0.34 ppm. RQ value > 1 both real-time and lifetime. As many as 63.6% of workershave real-time ECR >10 -4, and 81.8% of workers have ECR lifetime >10-4. This study concludes thatworkers are in an unsafe condition and have non-carcinogenic and carcinogenic health risks.
The Effect of Nitric Oxide Supplement Intake on the Value of Hematological Examination of Health Workers Exposed to Covid-19 Didik Dwi Winarno; Abdul Rohim Tualek; Noeroel Widajati; Juliana Jalaludin; Nuh Huda; Raden Khairiyatul Afiyah; ,Firman Suryadi Rahman
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14706

Abstract

Objective: Examination of the diagnostic covid-19 gold standard with real time reverse polymerase chainreaction (RT-PCR) is still limited, so that the initial hematological examination (leukocytes, lymphocytes,neutrophils, platelets, hemoglobin, and neutrophil lymphocyte ratio (NLR) plays an important role inmonitoring the course of covid-19 disease Macrophages release nitric oxide (NO) to kill parasites NOinhibits migration and adhesion of leucocytes to the endothelium. Metode: The research design used preexperimental with one group pre-post test, the total sample was 80 health workers who were exposed toCovid-19, the independent variable was the provision of NO and the dependent variable was the result ofa hematological examination (leukocytes, lymposites, platelets, neutrophils, hemoglobin and NLR). Theintervention was given NO 500 mg mixed with warm water 250 cc, given 3 times a day for 5 days, dataanalysis used the T-test with a significance value of a<0.05. Results: There is a difference in the resultsof the pre and post-test hematology giving NO to the results of the examination of leucocytes a=0.001,lymphocytes a=0.000, platelets a=0.000, neutrophils a=0.000, hemoglobin a=0.031, and NLR a=0.000.Conclusion: Giving NO to health workers exposed to Covid-19 can improve the hematology and immunesystems to fight the corona virus.
Hubungan Paparan Toluena di Udara dengan Fungsi Ginjal Pada Pekerja Bengkel Pengecetan Mobil Surabaya Dewi Cindy Putri Anggraini; Ahsan Ahsan; juliana Jalaludin
Media Gizi Kesmas Vol. 11 No. 1 (2022): Juni 2022
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v11i1.2022.116-120

Abstract

ABSTRAK Latar Belakang:Toluena merupakan salah satu bahan kimia yang termauk dalam pelarut oganik yang bersifat volatile atau mudah menguap. Salah satu efek yang ditimbulkan dari paparan toluena adalah adanya penurunan fungsi ginjal pada kelompok yang terpapar. Salah satu pemeriksaan yang digunakan untuk melihat fungsi ginjal pada seseorang adalah dengan melakukan pemeriksaan kadar kreatinin dan BUN.Tujuan: untuk melihat kadar kreatinin dan BUN pada pekerja sebagai suatu pemeriksaan terhadap fungsi ginjal.Method: Penelitian ini menggunakan penelitian deskriptif dengan menggunakan pendekatan kuantitatif. Penelitian bersifat observasioanl dengan menggunakan rancangan Cross Sectional Study.Populasi dalam penelitian ini adalah seluruh pekerja di bengkel pengecatan mobil Surabaya yang berjumlah 20 orang.Hasil: hubungan antara paparan toluena dengan kadar kreatinin dan BUN pada pekerja bersifat lemah dan searah (koefisien korelasi= 0,244 dan 0,042). Sementara itu untuk hubungan antara kadar kreatinin dan BUN dengan karakteristik responden juga bersifat lemah. Lemahnya hubungan antar variabel dapat diakibatkan oleh berbagai faktor lain. Kesimpulan: paparan toluena yang melebihi nilai ambang batas dan dalam waktu yang lama dapat menyebabkan suatu gangguan kesehatan salah satunya adalah penurunan fungsi ginjal. Sehingga pekerja harus memakai APD selama bekerja serta menjaga personal hygiene dengan baik. Kata kunci: paparan toluena, ginjal, kadar kreatinin, kadar BUN
COKELAT HITAM SEBAGAI MAKANAN KAYA NITRIC OXIDE UNTUK MENANGGULANGI COVID-19: SYSTEMATIC REVIEW: Dark Chocolate and Its Preventive Effect from Covid-19 Abdul Rohim Tualeka; Zulfa Anida; Ahmad Ridoi Yuda Prayogi; Juliana Jalaludin; Syamsiar S Russeng; Ahsan Ahsan; Indri H Susilowati; Pudji Rahmawati; Ayik Mirayanti Mandagi
Jurnal Kesehatan Masyarakat Andalas Vol 16 No 1 (2022): Jurnal Kesehatan Masyarakat Andalas
Publisher : Faculty of Public Health, Andalas University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24893/jkma.v16i1.1163

Abstract

Coronavirus 19 is a deadly disease that can kill thousands of people worldwide. However, not many researchers know that NO content can kill the COVID-19 virus. This research method is study design used retrospective methods, prospective and a systematic review. Search for reference sources began on March 10th - June 1st, 2021, using several online databases: 1) Pubmed, 2) Science Direct, 3) Google Scholar. Keywords used in the search term: COVID-19, Novel Coronavirus, SARS-CoV, Nitric Oxide, Dark Chocolate, Macrophages and included in journals accredited. This study looked for a list of references from the study, including 103 studies taken through the search. There are 63 articles in cleaning, and eight articles are included in the discussion. This review shows that COVID-19 can be attenuated and killed by the NO content produced by macrophages and supplied with NO content modulated by dark chocolate. Modulating NO-rich foods such as dark chocolate can effectively kill COVID-19. NO can also cure several diseases such as high blood pressure, diabetes, cardiovascular disease, and some respiratory infections.