Claim Missing Document
Check
Articles

Found 4 Documents
Search

Ekstensifikasi Budidaya Tanaman Herbal di Desa Pace Kecamatan Silo Kabupaten Jember Menuju Desa Sentra Herbal Vega Kartika Sari; Iqbal Erdiansyah; Eliyatiningsih Eliyatiningsih; Dwi Nurahmanto
Jurnal Pengabdian Magister Pendidikan IPA Vol 5 No 2 (2022): April-Juni
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (624.517 KB) | DOI: 10.29303/jpmpi.v5i2.1554

Abstract

Silo District is the largest ginger producing area in Jember which has great potential to be developed as an agricultural center. Several farmers in Pace Village have developed medicinal plants other than coffee plants. One of the strategies for developing medicinal plants is the preparation of appropriate cultivation technology. Efforts to realize Pace Village to become a Medicinal herbs Center Village need to be continuously supported and assisted in order to increase the quantity and quality of production. This community service activity was carried out as a follow-up to mentoring in Year 1. The activity in this second year aims to provide extensive assistance in the cultivation of medicinal plants by increasing the unit area for planting and improving cultivation production inputs to optimize and develop medicinal plant cultivation in Pace Village. The expansion of the planting area was carried out on land belonging to the village and in several yards of Gapoktan members. Improvement of production inputs through the construction of a nursery managed by the Taman Rizki Farmers Group, the addition of types of medicinal plants, and agricultural tools to support the success of medicinal herbs cultivation towards Pace Village as a Medicinal Herbs Center in Jember Regency.
FORMULATION AND OPTIMIZATION OF CAFFEINE NANOEMULSION USING FACTORIAL DESIGN STUDY Bannan Muthi’atul Af-idah; Dwi Nurahmanto; Dessy Dwi Risky
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Caffeine was an alkaloid commonly used as activeingredient in cosmetics due to its high biologicalactivity for skin health as anticelulit, sunscreen,antioxidant, and photoaging inhibitor [6]. Caffeinehad potential antioxidant properties that couldprotect cells against the UV radiation inducecarcinogenesis with stimulatory effect on apoptosisin the UVB-treated epidermis cell in mice skin [8].High hidrophilic properties of caffeine (log P = -0.07)caused difficulties to penetrate through the stratumcorneum of human skin [9]. Nanoemulsion was adrug delivery system that had good stability andcould potentially increase penetration of the drugthrough the skin that had particle size approximately1 – 100 nm. Oil phase, aqueous phases, andsurfactant are basic component of nanoemulsion[11]. Surfactant was the important compound inpreparation of nanoemulsion. Type, amount ofsurfactant, and HLB value of surfactant can influencenanoemulsion stability [1]. Isopropyl miristate (IPM)was chemical penetration enhancer (CPE), wasadded in skin drug formulation to incrase thepenetration ability of the drug [3]. This study aimedto investigate the effect of hydrophile lipophilebalance (HLB) value of surfactant combination(tween 80 and span 80) and IPM concentration onthe stability and penetration ability of nanoemulsionusing factorial design method and obtain theoptimum formula of caffeine nanoemulsion usingDesign Expert 9.0 analysis.
OPTIMASI ASAM TARTRAT DAN NATRIUM BIKARBONAT GRANUL EFFERVESCENT KOMBINASI EKSTRAK DAUN Guazuma ulmifolia Lam. DAN KELOPAK Hibiscus sabdariffa L. Dwi Nurahmanto; Dita Isnaini Prabawati; Bawon Triatmoko; Nuri Nuri
Jurnal Farmasi UIN Alauddin Makassar Vol 7 No 2 (2019): Jurnal Farmasi Volume 7 Nomor 2
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v7i2.11573

Abstract

Guazuma ulmifolia Lam. dan Hibiscus sabdariffa L. secara empiris digunakan sebagai jamu untuk menurunkan kadar kolesterol dalam darah. Jamu yang mengandung ekstrak tersebut memiliki rasa yang pahit dan aroma yang tidak menyenangkan. Penelitian ini dibuat sediaan granul effervescent dari kombinasi ekstrak daun Guazuma ulmifolia Lam. dan ekstak Kelopak Bunga Hibiscus sabdariffa L. Formulasi dalam bentuk granul effervescent, terdiri dari sumber asam dan basa yaitu asam tartrat dan natrium bikarbonat. Granul effervescent dapat memperbaiki rasa dan aroma. Penelitian ini bertujuan untuk mengetahui formula optimum yang memiliki sifat fisik granul effervescent yang baik.  Penelitian ini dilakukan berdasarkan metode desain faktorial dengan dua faktor dan dua level yang menghasilkan empat formula yaitu formula (1), a, b, dan ab. Sifat fisik granul effervescent yang diuji adalah kelembaban dan waktu larut. Hasil menunjukkan bahwa peningkatan konsentrasi natrium bikarbonat dapat menurunkan kelembaban dan waktu larut. Sedangkan, peningkatan konsentrasi asam tartrat justru sebaliknya. Formula optimum yang diperoleh dalam penelitian ini mengandung asam tartrat 600 mg dan natrium bikarbonat 1209 mg. Formula tersebut memiliki komposisi yang sama seperti formula b.
Pengembangan Essence dari Ekstrak Kayu Secang (Caesalpinia sappan L.) Lidya Ameliana; Budipratiwi Wisudyaningsih; Dwi Nurahmanto; Yenika Ayu Mega Dianatri
JURNAL ILMU KEFARMASIAN INDONESIA Vol 20 No 1 (2022): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v20i1.1139

Abstract

Sappan wood (Caesalpinia sappan L.) was reported to have natural antioxidant properties. Brazillin is the compound responsible for its antioxidant effect. Antioxidants are needed to prevent premature aging of the skin. Essence is a cosmetic that contains topical antioxidants. Essence has advantages over other skincare products, and essence is easier to absorb into the skin. The objective of the present study was to optimize and evaluate the Essence of sappan wood ethanolic extract for treatment as a cosmetic antioxidant. Simplex lattice design was adopted to evaluate the effect of butylene glycol and glycerin concentration on Essence characteristics. The method used in the extraction is maceration with ethanol solvent. The results showed that both butylene glycol and glycerin significantly enhanced the viscosity and pH value of the sappan essence formulation. The optimum Essence formula consisted of 10% butylene glycol with a predicted viscosity value of 2,944 dPas and a pH of 5,075. The characteristics of the optimum formula of sappan wood extract Essence have a thick texture, a characteristic odor of colored extract brownish yellow, homogeneous, and has a spreadabillity of 14 cm.