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Hematological Test: Predicting Incidence Dengue Shock Syndrome Imam Syahputra Yamin; Tri Yunis Miko Wahyono
Biota Vol 14 No 2 (2021)
Publisher : Universitas Islam Negeri Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20414/jb.v14i2.387

Abstract

Dengue hemorrhagic fever (DHF) is an infectious disease caused by the Dengue virus. DHF cases in Mataram City from 2016 to 2020 tend to increase where most of the DHF patients are treated at the Mataram City Hospital. Death due to DHF infection mostly occurred in patients with Dengue Shock Syndrome (DSS) and mortality from DSS was reported to be 50 times higher than in DHF patients without DSS. Prompt diagnosis and appropriate treatment are important determinants for the prevention and control of dengue cases, so knowing the predictors of risk factors can prevent/reduce deaths from dengue virus. This study used a case-control design. Cases were DHF patients diagnosed with DSS by the treating doctor, while the controls were DHF patients diagnosed not DSS by the treating doctor. The research data was obtained from the results of laboratory tests stored in the medical records of patients treated at the Mataram City Hospital from January 2016 to December 2020. The design of the analysis was aimed at obtaining the odds ratio (OR) value followed by multivariate analysis to determine the risk factors that could detect DSS earlier. The variables that were statistically significant in the prediction of the final model were the increase in hematocrit value > baseline with OR= 17.1 (95% CI: 4.033-72.600), a decrease in platelet value < 100.000/µL with OR = 6 (95% CI). : 2,306-15,699), and decreased leukocyte value < baseline with OR= 5.1 (95% CI: 2,209-11,838). While the most dominant variable is the increase in hematocrit value > baseline with OR = 17.1 (95% CI: 4.033-72.600) and p value = 0.000.
Uji Aktivitas Antiradikal Biji Pare (Momordica charantia L) Menggunakan Metode DPPH Serta Analisis Metabolit Sekundernya Baiq Desy Ratnasari; Diah Miftahul Aini; Imam Syahputra Yamin; Gladeva Yugi Antari
Jurnal Ilmiah Medicamento Vol 8 No 1 (2022): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v8i1.3352

Abstract

Momordica charantia L seed is classified as the domestic waste even though it has many health benefits, namely as anti-tumor, anti-virus, and as a medicine to increase the body resistance. Therefore, this study was designed to examine the antioxidant activity of the ethanol extract of the seeds using the DPPH method. Furthermore, a GC-MS analysis will be carried out to determine the chemical compounds that play a role in the bioactivity. Based on the absorbance of DPPH in three repetitions, the average value of DPPH inhibition by 95% ethanol extract of bitter melon seeds was 60.45%, in which classified as a good radical absorbance. The GC-MS results showed that the ethanol extract of bitter melon seeds contained ten chemical compounds consisting of sesquiterpenes, fatty acids, and alkanes, which affecting the radical absorbance of M. charantia extract.
SOSIALISASI PENGEMBANGAN KAMPUNG SWAMEDIKASI COVID-19 BERBASIS RAMUAN TRADISIONAL Imam Syahputra Yamin; Baiq Desy Ratnasari
JMM (Jurnal Masyarakat Mandiri) Vol 6, No 6 (2022): Desember
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v6i6.11247

Abstract

Abstrak: Upaya swamedikasi menjadi solusi dalam masa pandemi Covid-19 dalam memberikan daya imunitas tubuh. Didukung dengan sumber daya pekarangan rumah untuk dijadikan apotek hidup. Terlebih upaya swamedikasi dapat mengobati penyakit ringan, mencegah penyakit, merawat tubuh, dan menjaga kesehatan. Tujuan dilakukan sosialisasi adalah untuk memberikan pemahaman terkait upaya swamedikasi Covid-19 berbasis ramuan tradisional. Pelaksanaan kegiatan ini melibatkan mitra desa sejumlah 28 orang dari unsur Kelompok Taruna Tani dan Karang Taruna Desa Setungkep Lingsar. Metode yang dilakukan dengan diskusi dua arah serta memberikan paparan materi terkait covid19 dan pemanfaatan tanaman obat. Dalam kegiatan sosialisasi didapatkan ada peningkatan pemahaman 82% dari hasil pre-test menjadi 98% pada post-test, sehingga dapat disimpulkan terdapat peningkatan pemahaman sesudah diberikan edukasi terkait Covid-19 dan tanaman obat.Abstract: Self-medication efforts are a solution during the Covid-19 pandemic in providing body immunity. Supported by the resources of the yard of the house to be used as a living pharmacy. Moreover, self-medication efforts can treat minor illnesses, prevent disease, take care of the body, and maintain health. The purpose of the socialization is to provide an understanding of the efforts to self-medicate Covid-19 based on traditional ingredients. The implementation of this activity involved 28 village partners from elements of the Tani Group and the Setungkep Lingsar Village Youth Organization. The method is carried out with two-way discussions and provides exposure to material related to COVID-19 and the use of medicinal plants. In the socialization activity, it was found that there was an increase in understanding of 82% from the pre-test results to 98% in the post-test, so it can be concluded that there was an increase in understanding after being given education related to Covid-19 and medicinal plants.
The Genetic Diversity of Macroalgae on The Ekas Coast of East Lombok Based on Chromatogram Data from PCR Ampification Baiq Repika Nurul Furqan; Imam Syahputra Yamin; Sri Sofiati Umami
Biota Vol 16 No 1 (2023)
Publisher : Universitas Islam Negeri Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20414/jb.v16i1.417

Abstract

Macroalgae are multicellular photosynthetic organisms that live in water. Some species of macroalgae are very difficult to identify based on their morphology alone because they have great similarities. Therefore, identification of macroalgae diversity based on its genotype is very important to do in order to enrich the genetic information of macroalgae found on one of the beaches on the island of Lombok. This study aimed to analyze the genetic diversity of macroalgae from Pantai Ekas Beach, Jeowaru District, East Lombok, NTB using 18S rRNA gene markers. The research was carried out in 4 stages, namely sampling, morphological analysis of samples, isolation of total macroalgae DNA, isolation of genes by PCR amplification, agarose gel electrophoresis. Sampling was carried out at certain coordinates at east longitude and south latitude using the Ekas Beach quadratic transect method. The morphological analysis of the samples was guided by an identification key. Total DNA, macroalgae were isolated based on the spin column I DNA kit easy method. Genes were isolated by means of PCR amplification. Total DNA isolates and gene amplicons were confirmed by agarose gel electrophoresis. The results obtained were based on their morphology, all samples obtained were grouped into 9 macroalgae samples which could be divided into brown macroalgae (3 samples), green macroalgae (2 samples) and red macroalgae (4 samples). All samples have successfully isolated total DNA and its 18S rRNA gene which was confirmed by agarose gel electrophoresis chromatogram.