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Association between the Duration of Steroid Therapy with Hyperglycemia in Patients with Systemic Lupus Erythematosus (SLE) Widyanrika, Farahdiva Audrey; Mudjanarko, Sony Wibisono; Rochmanti, Maftuchah; Ardiany, Deasy; Permana, Putu Bagus Dharma
Current Internal Medicine Research and Practice Surabaya Journal Vol. 5 No. 1 (2024): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v5i1.53043

Abstract

Introduction: Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease which primary treatment consists of steroid drugs administration. Prolonged steroid administration is often associated with an increase in blood glucose, a condition known as hyperglycemia. Hence, this study aimed to evaluate the association between the duration of steroid therapy with hyperglycemia in patients with SLE treated at a tertiary healthcare center in Surabaya, Indonesia.Methods: A cross-sectional study was conducted under a purposive sampling frame from January to December of 2022 by utilizing secondary data from electronic medical health records in Dr. Soetomo General Academic Hospital, a tertiary healthcare center in Surabaya, Indonesia. The association between variables were analyzed using Fisher's exact test, chi square test, independent T-test, one-way ANOVA, Mann-Whitney, and Spearman's rank correlation.Results: Out of 150 included patients, 2.67% experienced hyperglycemia following steroid therapy for SLE. There were no significant associations between clinical variables and hyperglycemia occurence in SLE patients (p>0.05). Patients that received higher doses of steroid did not experience any significant difference in hyperglycemia (p=0.727 for <6 months; p=0.865 for ≥6 months). Daily steroid dose was also not significantly associated with the severity of SLE manifestations based on the SLEDAI score (p=0.081). Overall, no significant association was identified between the duration of steroid therapy with hyperglycemia among SLE patients in the hospital (p=0.365). Conclusion: The study found no significant correlation between clinical variables, hyperglycemia incidence, daily steroids dosage, methylprednisolone dosage, SLE severity, or steroid use duration in patients with Systemic Lupus Erythematosus.
The use of a Scorecard to Evaluate the Public’s Comprehension of COVID-19: A Pilot Study Kalanjati, Viskasari Pintoko; Hasanatuludhhiyah, Nurina; d'Arqom, Annette; Arsyi, Danial Habri; Permana, Putu Bagus Dharma; Pratiwi, Octaviana Galuh; Farabi, Moh. Reza; Susila, I Made Dwi Yudiartana Putra; Yudhono, Anggit Satriyo; Brilianti, Natasya Nurvita
Jurnal Keperawatan Soedirman Vol 17 No 3 (2022): Jurnal Keperawatan Soedirman (JKS)
Publisher : Fakultas Ilmu-ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (231.523 KB) | DOI: 10.20884/1.jks.2022.17.3.6572

Abstract

The rapid spread of information and infodemic might result in public confusion and hinder the handling of the COVID-19 pandemic. Public comprehension of COVID-19 as part of health literacy is an important determinant to filter hoaxes from facts. Therefore, a scoring card called the Karlivid (the COVID-19 literacy and public vaccination scorecard) was developed to evaluate the individual’s comprehension level of COVID-19. A pilot study was conducted with this scoring card. The participants were recruited via consecutive random sampling by using emails from the researcher’s contact list (n=92). A total of 78.3% of the respondents were considered to have an adequate comprehension level. Approximately 77% of all respondents agreed that this card could help them know their comprehension level, 81.5% agreed that this card could improve their comprehension, 81.5% agreed that the items in this card could help them screen facts from hoaxes, and 81.5% agreed that the language used was easily understood by the laypersons. Therefore, the Karlivid is a valid and reliable scorecard that can be used to evaluate public comprehension of COVID-19. Most of the respondents also had a good level of comprehension of this assigned topic
Differences in Chest X-Ray Imaging in Pulmonary Tuberculosis across Various Comorbidities Subkhan, Mohammad; Rezacharawa, Meltritania Arief; Putra, Muslim Andala; Laitupa, Afrita Amalia; Permana, Putu Bagus Dharma; Irfana, Laily
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 11, No 2 (2024): August
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.11.2.2024.169-180

Abstract

Background:  Tuberculosis (TB) remains a significant public health concern in Indonesia, with a high prevalence of cases, particularly in patients with comorbidities such as HIV infection, chronic obstructive pulmonary disease (COPD), diabetes mellitus (DM), and chronic kidney disease (CKD). Evidence suggested radiological variations in chest X-ray findings among these complex condition, which may pose significant challenges in accurately diagnosing pulmonary TB in clinical practice.Objective:  This study aimed to provide a comprehensive understanding of the variations in chest X-ray imaging in pulmonary TB patients with specific comorbidities, focusing on DM, CKD, and COPD.Methods: A cross-sectional study was conducted at Siti Khodijah Muhammadiyah Sepanjang Hospital by utilizing standardized medical records and chest X-ray results of 50 pulmonary patients with comorbidities.Results: The most prevalent comorbidity was DM, with radiological findings including fibroinfiltrates, consolidations, and cavities. CKD patients exhibited radiological features such as infiltrates, cavitations, and pleural effusion, while COPD patients presented with infiltrates and consolidations. Conclusion: The study provides valuable insights into the radiological manifestations of pulmonary TB and its comorbidities, offering a basis for improved management and treatment strategies for patients with pulmonary TB and comorbidities. Further research employing longitudinal designs and balanced representation of comorbid conditions is recommended to enhance the understanding of the interplay between TB and associated health conditions.
Type 2 Diabetes Mellitus Status with Ankle-Brachial Index among Patients with Diabetic Foot Ulcer at Universitas Airlangga Hospital, Surabaya Anisah, Hana; Limanto, Danang Himawan; Suryantoro, Satriyo Dwi; Utomo, Budi; Permana, Putu Bagus Dharma
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 15 No. 1 (2024): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V15I12024.51-56

Abstract

Highlights: ABI was not influenced by diabetic status due to potential confounders. A more severe form of diabetic ulcer was associated with a lower ABI value.   Abstract Introduction: Diabetic foot ulcer (DFU) is one of the most significant complications of uncontrolled type 2 diabetes mellitus (T2DM) that may affect a patient's prognosis and quality of life. This study aimed to identify the association between diabetic status, DFU severity, and other clinical factors with ankle-brachial index (ABI) score and category. Methods: This was a cross-sectional study under a consecutive sampling frame conducted from 1 November 2022 to 31 January 2023 at Universitas Airlangga Hospital, Surabaya. Primary data for ABl were measured from T2DM patients with DFU in the Thoracic and Cardiovascular Polyclinic. Meanwhile, secondary clinical data were collected from the Department of Internal Medicine based on the inclusion and exclusion criteria specified in the patient's medical records. The International Business Machines Corporation (IBM) Statistical Package for Social Sciences (SPSS) version 26 was utilized for the statistical analysis. Results: Out of 30 included patients, 63.33% had uncontrolled diabetic status, and the average ABI score was 0.999 ± 0.19. DFU severity was significantly associated with the ABI score and ABI category. Patients indicated with angioplasty exhibited a markedly lower ABI score than those without (mean 0.32 vs 1.01; p < 0.001). Indication of angioplasty was the only clinical factor significantly associated with a lower ABI score (p < 0.001). Conclusion: The status of T2DM was unrelated to ABI. Future research is recommended to advance the understanding of peripheral artery disease in diabetic foot ulcer patients.