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All Journal Pharmascience Jurnal Pengabdian kepada Masyarakat
Yuana Sukmawaty
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Agriculture, Biological Sciences & Forestry Humanities Economics, Econometrics & Finance Environmental Science Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences Other

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SOSIALISASI DAN PENDAMPINGAN INOVASI SULAM PITA PADA MEDIA KERAJINAN PURUN DI KOTA BANJARBARU Yuana Sukmawaty; Dewi Anggraini; Aprida Siska Lestia; Nada Agustina; Anita Khumaida; Fatiya Hanifah; Rabiatul Zannah; Siti Jubaidah
J-ABDI: Jurnal Pengabdian kepada Masyarakat Vol. 1 No. 11: April 2022
Publisher : Bajang Institute

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Abstract

Purun woven is a local cultural inheritance that must be preserved its local wisdom. Currently, there are many product derivatives from this craft, one of which is a tote bag that is useful for reducing plastic waste when going shopping to malls and markets. This tote bag made from the purun swamp plant that grows around swamp and peat land in South Kalimantan Province is better known as the purun basket. The Micro, Small and Medium Enterprises (UMKM) and local creative industries, especially in Banjarbaru City, which has started to innovate with this purun basket has made the purun basket more widely known to foreign countries, including doing ribbon embroidery techniques on the purun basket media. Therefore, it is necessary to socialize this form of ribbon embroidery innovation to the public so that it is more widely known. This service aims to introduce additional skills in ribbon embroidery techniques to the administrators of the Women's Organization Association (GOW) of Banjarbaru City, as well as to increase the enthusiasm of the purun craftsmen in Banjarbaru City. The hope is that these skills can increase income for audiences that come from the administrators of the Women's Organization Association (GOW) of Banjarbaru City in spare time. The results of this service were enthusiastically welcomed by the management, who are also residents of the City of Banjarbaru and a special award among craftsmen because their work is widely recognized
Identifikasi Fitokimia dan Uji Aktivitas Antiinflamasi In vitro Fraksi n- heksana Kapur Naga (Calophyllum soulattri Burm F) Dengan Metode Uji Penghambatan Denaturasi Protein Menggunakan Spektrofotometer Uv-Vis Fadlilaturrahmah Fadlilaturrahmah; Jariyah Amilia; Yuana Sukmawaty; Nashrul Wathan
Jurnal Pharmascience Vol 9, No 2 (2022): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v9i2.14372

Abstract

Tumbuhan kapur naga (Calophyllum soulattri Burm F) merupakan salah satu spesies dari  keluarga Calophyllum yang terdapat di hutan Kalimantan khususnya daerah lahan basah. Secara empiris dimasyarakat memanfaatkan kulit batang C. soulattri untuk mengobati penyakit kulit yang salah satu mekanisme proses penyembuhan melawati tahap inflamasi. Penelitian ini bertujuan untuk melakukan penulusuran kandungan fitokimia dari fraksi n-heksana kulit batang C. soulattri dan melakukan uji aktivitas antiinflamasi in vitro dengan metode uji penghambatan denaturasi protein menggunakan spektrofotometer uv-vis. Metode penelitian diawali dengan tahapan pembuatan simplisia, ekstraksi dengan etanol 96%, dan difraksinasi menggunakan n-heksana.  Setelah itu dilakukan  uji penelusuran kandungan fitokimia menggunakan uji tabung dan pengujian antiinflamasi menggunakan spektrofotometri uv-vis menggunakan metode penghambatan denaturasi protein secara kuantitatif dengan natrium diklofenak sebagai kontrol positif. Hasil dari identifikasi fitokimia diperoleh bahwa fraksi n-heksana mengandung alkaloid, fenol, tanin, flavonoid, saponin, dan triterpenoid. Uji aktivitas antiinflamasi fraksi n-heksana kulit batang C. soulattri menghasilkan nilai IC50 sebesar 27,43±0,74 ppm dan natrium diklofenak dengan nilai  IC50 sebesar 39,17±0,86 ppm. Berdasaran uji t-test diperoleh hasil yang menunjukkan berbeda bermakna  dengan IC50 Natrium diklofenak (sig = 0,00). Kesimpulan dari penelitian ini yaitu fraksi n-heksana kulit batang C. soulattri memiliki aktivitas antiinflamasi yang lebih baik dari natrium diklofenak. Kata Kunci: Bovine Serum Albumin, IC50, Natrium Diklofenak, Kuantitatif Kapur naga (Calophyllum soulattri Burm F) is a species of the Calophyllum family that found in the forests of Kalimantan, especially in wetland areas. Empirically, the community uses the bark of C. soulattri to treat skin diseases, which is one of the mechanisms of the healing process through the inflammatory stage. The purpose of this study was to investigate the phytochemical content of the n-hexane fraction of the stem bark of C. soulattri and to test its anti-inflammatory activity in vitro with the protein denaturation inhibition test method using uv-vis spectrophotometer. The research method begins with the steps of making simplicia, extraction with 96% ethanol, and fractionation using n-hexane. After that, a test for tracing the phytochemical content was carried out using a tube test and an anti-inflammatory test using uv-vis spectrophotometry using a quantitative protein denaturation inhibition method with diclofenac sodium as a positive control. The results of the phytochemical identification showed that the n-hexane fraction contained alkaloids, triterpenoids, phenols, tannins, flavonoids, and saponins. The anti-inflammatory activity test of the n-hexane fraction of C. soulattri stem bark produced an IC50 value of 27.43±0.74 ppm and diclofenac sodium with an IC50 value of 39.17±0.86 ppm. Based on the t-test, the results showed that it was significantly different from the IC50 of diclofenac sodium (sig = 0.00). The conclusion of this study is that the n-hexane fraction of the stem bark of C. soulattri has better anti-inflammatory activity than diclofenac sodium.
Co-Authors Anita Khumaida Dewi Anggraini Dewi Anggraini Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fatiya Hanifah Jariyah Amilia Lestia, Aprida Siska Nada Agustina Nashrul Wathan Rabiatul Zannah Siti Jubaidah