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All Journal Jurnal Kesehatan Prima Jurnal Analis Medika Biosains (JAMBS)

Ersandhi Resnhaleksmana

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Author-ID : 2390667

Biochemistry, Genetics & Molecular Biology Health Professions Nursing Public Health

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Hubungan Kepadatan Parasit Terhadap Kadar Hemoglobin Pada Penderita Malaria Asimtomatik Di Gunung Sari Ermadiana Agustin; Ersandhi Resnhaleksmana; I Wayan Getas
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 1 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i1.260

Malaria is an infectious disease that still provides a high morbidity rate in the world. Malaria affects almost all blood components, one of which is hemoglobin levels. In malaria infection, there is a decrease in hemoglobin levels due to the destruction of excessive red blood cells by the malaria parasite. Asymptomatic malaria infection plays an important role in malaria transmission as it is a major influence on ongoing treatment-based malaria control programs. The research objective in this study was to know the effects of parasite density on hemoglobin levels in patients with Asymptomatic Malaria disease in Gunung Sari. The research study used is an analytic observational study with a Cross-Sectional approach with the Accidental sampling method and the Consecutive sampling method. The result of the study is out of the 14 samples diagnosed with asymptomatic malaria, 12 people (85.7%) had a mild degree of parasitemia based on parasite density calculations (8-800 / μl), and 2 people (14.3%) had moderate degrees of parasitemia (801- 8800 / μl). As many as 6 people (42.9%) had normal Hb levels, and 8 people (57.1%) had Hb levels below normal values. The conclusion of this study proved that there is a significant correlation between parasite density and hemoglobin levels in asymptomatic malaria patients in Gunung Sari.

THE USE OF BLACK SOYBEAN (Glycine max L) EXTRACT AGAINST THE ACTIVITY OF LIVER ENZYMES (AST - ALT) AND ANTIOXIDANT SUPEROXIDE DISMUSTASE (SOD) OF WHITE RAT I Gusti Ayu Nyoman Danuyanti; Ersandhi Resnhaleksmana
Jurnal Kesehatan Prima Vol 12, No 1 (2018): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Abstract: Strenuous physical activity can increase the activity of enzymes AST (aspartate aminotransaminase) and ALT (alanine aminotransaminase) in the blood as a sign of hepatic dysfunction caused by oxidative stress as a result. Excessive free radicals that damage macromolecules in cells. The supplementation of black soybean (Glycine max L) contains anthocyanin as an antioxidant is expected to reduce the formation of free radicals thus the activity of liver enzymes and the levels of SOD enzymes as intracellular antioxidant can be maintained. The purpose of this study was to determine the effect of using extracts of black soybean (Glycine max L) on the activity of liver enzymes (AST-ALT) and the antioxidant superoxide dismutase (SOD) of white rats that were given a maximum of physical activity. The research was control group post test design in vivo that used black soya extract treatment given to white rats (Rattus norvegicus) Wistar strain given maximum physical activity. The results indicated black soybean extract 40% was the most powerful retaining the activity of liver enzymes and blood levels of antioxidants SOD. The conclusion is there is an effect of black soybean extract against the activity of liver enzymes (AST-ALT) in rats given maximal activity, whereas SOD enzymes can inhibit the decline of SOD enzyme level to 37.8% but statistically there is no significant influence.Keywords: AST-ALT enzymes; antioxidants SOD; Soybean black; Physical activity maximum.

STUDI TOXOPLASMOSIS PADA PENDERITA SCHIZOPHRENIA DI RUMAH SAKIT JIWA PROVINSI NTB Ersandhi Resnhaleksmana; Nursardjan Nursardjan; I Gusti Ayu Nyoman Danuyanti
Jurnal Kesehatan Prima Vol 8, No 1 (2014): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Abstract: Toxoplasmosis, a disease caused by Toxoplasma gondii, a parasite of humans and animals scattered throughout the world. Infection T. gondii into the body of most real place in the reticuloendothelial tissues and the brain with symptoms of central nervous system often leave residual symptoms, such as mental and motor retardation. This phenomenon often occurs in people with schizophrenia. This study aims to determine the toxoplasmosis in patients with schizophrenia in Rumah sakit jiwa Provinsi NTB. The Methods of This study used an observational analytic design with cross-sectional design to determine the percentage of toxoplasmosis, by examination of the ELISA for determination of IgG T. gondidi serum samples of patients with schizophrenia at Rumah Sakit Jiwa Provinsi NTB. The research was conducted in July-November 2011, with a total sample size is 42 people. The idependent variabel is Toxoplasmosis and the dependent variabel is patient with schizophrenia.There is a percentage of toxoplasmosis in patients with schizophrenia was 54.8% (23 people) with higher levels of IgG T. gondii highest was 300 UI / ml. From the results of this study indicate the presence of infection T. gondii in patients with schizophrenia at Rumah Sakit jiwa Provinsi NTB.

HUBUNGAN KADAR NITRIT OKSIDA (NO) DALAM DARAH TERHADAP RESIKO KEJADIAN DIABETES MELLITUS TIPE 2 DENGAN HIPERTENSI DI RSUP NTB I Gusti Ayu Nyoman Danuyanti; Erna Kristinawati; Ersandhi Resnhaleksmana
Jurnal Kesehatan Prima Vol 8, No 1 (2014): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Abstract: Diabetes Mellitus (DM) is a group of metabolic diseases with characteristic hyperglycemia that occurs due to abnormalities in insulin secretion, insulin action or both. Pathophysiology of type 2 diabetes mellitus are very complex with involving a variety of factors, including nutrition, obesity, sedentary lifestyle, and lack of physical activity, and genetik. The prolonged of condition hyperglycemia causes endothelial cell dysfunction resulting in decreased production of various compounds that are antithrombotic and vasodilating include nitric oxide ( NO). The purpose of this study was to determine the relationship between levels of nitric oxide (NO) in the blood against the risk of incident type 2 diabetes mellitus with hypertension at the RSUP NTB. This study uses a case-control design, with a sample size of 30 people with type 2 diabetes with hypertension as the case group and 30 patients without hypertension, diabetes mellitus type as the control group. The total sample is 60 people. Dependent variable in this study is the levels of NO in the blood while the independent variables of type 2 DM patients with hypertension. Determination of levels of nitric oxide (NO) in the blood using spectrophotometric methods. Correlation test is used to determine the relationship between levels of nitric oxide (NO) in blood with the blood pressure while Chi-square test used to determine the relationship of NO levels on the risk of incident type 2 diabetes with hypertension. The results showed average mean levels of NO in patients with type 2 diabetes with hypertension was lower than 0.54 μM with type 2 DM patients without hypertension is 1.32 μM. The results of correlation test levels of NO in the blood and blood pressure showed p-value = 0.000 (<α 0.05) and there is a strong relationship with a correlation coefficient value of 0.749 for systolic blood pressure and 0.694 for diastolic. Analysis of the relationship of NO levels in the blood against the risk of incident type 2 diabetes with hypertension show the value of p = 0.000. The overall from the can be concluded There is a relationship between the amount of nitric oxide (NO) in the blood against the risk of incident type 2 diabetes mellitus with hypertension in the RSUP NTB.

Co-Authors Ermadiana Agustin Erna Kristinawati I Gusti Ayu Nyoman Danuyanti I Wayan Getas Nursardjan Nursardjan

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