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All Journal Jurnal Kesehatan Prima Jurnal Analis Medika Biosains (JAMBS) Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram
Erna Kristinawati
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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HUBUNGAN KADAR NITRIT OKSIDA (NO) DALAM DARAH TERHADAP RESIKO KEJADIAN DIABETES MELLITUS TIPE 2 DENGAN HIPERTENSI DI RSUP NTB I Gusti Ayu Nyoman Danuyanti; Erna Kristinawati; Ersandhi Resnhaleksmana
Jurnal Kesehatan Prima Vol 8, No 1 (2014): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.272 KB) | DOI: 10.32807/jkp.v8i1.42

Abstract

Abstract: Diabetes Mellitus (DM) is a group of metabolic diseases with characteristic hyperglycemia that occurs due to abnormalities in insulin secretion, insulin action or both. Pathophysiology of type 2 diabetes mellitus are very complex with involving a variety of factors, including nutrition, obesity, sedentary lifestyle, and lack of physical activity, and genetik. The prolonged  of condition hyperglycemia causes endothelial cell dysfunction resulting in decreased production of various compounds that are antithrombotic and vasodilating include nitric oxide ( NO). The purpose of this study was to determine the relationship between levels of nitric oxide (NO) in the blood against the risk of incident type 2 diabetes mellitus with hypertension at the RSUP NTB. This study uses a case-control design, with a sample size of 30 people with type 2 diabetes with hypertension as the case group and 30 patients without hypertension, diabetes mellitus type as the control group. The total sample is 60 people. Dependent variable in this study is the levels of NO in the blood while the independent variables of type 2 DM patients with hypertension. Determination of levels of nitric oxide (NO) in the blood using spectrophotometric methods. Correlation test is used to determine the relationship between levels of nitric oxide (NO) in blood with the blood pressure while Chi-square test used to determine the relationship of NO levels on the risk of incident type 2 diabetes with hypertension. The results showed average mean levels of NO in patients with type 2 diabetes with hypertension was lower than 0.54 μM with type 2 DM patients without hypertension is 1.32 μM. The results of correlation test levels of NO in the blood and blood pressure showed p-value = 0.000 (<α 0.05) and there is a strong relationship with a correlation coefficient value of 0.749 for systolic blood pressure and 0.694 for diastolic. Analysis of the relationship of NO levels in the blood against the risk of incident type 2 diabetes with hypertension show the value of p = 0.000. The overall from the can be concluded There is a relationship between the amount of nitric oxide (NO) in the blood against the risk of incident type 2 diabetes mellitus with hypertension in the RSUP NTB.
Analisis Jumlah dan Jenis Bakteri Coccus Gram Positif pada Sisa Sampel Darah di Spuit Sofiyan Dwi Arfi; Erna Kristinawati; Ari Khusuma
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 2 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i2.270

Abstract

.Background: One of the problems in the field of health services that can increase the mortality rate is nosocomial infection. Waste containing pathogenic bacteria can serve as a medium for the spread of disease for health facility workers, sufferers and the public. One of the medical devices that have a high risk factor as an intermediary for infection is a syringe. Bacterial contamination of the syringe after use cannot be ignored. Therefore, further research is needed on waste in health facilities to determine infectious diseases caused by residual blood samples in the syringe. Research Objectives: To determine the presence of gram-positive coccus bacteria in the remaining blood sample in the syringe. Methods: This study used a descriptive observational method with a cross sectional approach to time. The sample size in this study was 14 samples with a sampling technique that is total sampling. Results: It was found that Staphylococcus aureus and Staphylococcus cohnii were found each of the 14 samples. Conclusion: There are gram-positive coccus bacteria, namely Staphylococcus cohnii and Staphylococcus aureus. 
EKSTRAK BUNGA CENGKEH SEBAGAI INSEKTISIDA TERHADAP MORTALITAS NYAMUK AEDES AEGYPTI METODE SEMPROT DRS IWAYAN GETAS,M.Sc Ariwidiani; Ariwidhiani; Erna Kristinawati
Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram Vol. 7 No. 2 (2021): JURNAL PENELITIAN DAN KAJIAN ILMIAH KESEHATAN POLITEKNIK MEDICA FARMA HUSADA MA
Publisher : Politeknik Medica Farma Husada Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (760.853 KB) | DOI: 10.33651/jpkik.v7i2.232

Abstract

Peningkatan kasus DBD di Indonesia pada tahun 2016 sebanyak 204.171 kasus dengan jumlah kematian sebanyak 1.598 orang. Berdasarkan data profil kesehatan Indonesia, telah terjadi peningkatan kasus DBD di setiap tahunnya. Peningkatan angka kesakitan DBD juga terjadi di NTB pada tahun 2016 yaitu sebesar 52,80 per 100.000 penduduk. Pemanfaatan bunga cengkeh sebagai bahan insektisida alami dapat menjadi alternatif yang lebih ramah lingkungan sehingga dapat menekan dampak negatif dari penggunaan insektisida kimia. Tujuan dalam penelitian ini adalah untuk menganalisis potensi ekstrak bunga cengkeh (Syzygium aromaticum) sebagai insektisida terhadap nyamuk Aedes aegypti dengan metode semprot. Penelitian ini merupakan penelitian eksperimental dengan post-test only controlled group design. Perlakuan dilakukan dalam 5 konsentrasi yaitu 5%, 10%, 15%, 20% dan 25%. Data yang diperoleh dianalisis secara statistic menggunakan uji Chi Square dan analisis probit. Berdasarkan hasil analisis, ekstrak bunga cengkeh (Syzygium aromaticum) berpotensi sebagai insektisida terhadap nyamuk Aedes aegypti dengan nilai signifikan 0.000 (p < 0.05) dengan konsentrasi LC50 diperoleh sebesar 3,434% dan LC90 sebesar 22,070%.
Co-Authors Ari Khusuma Ariwidhiani DRS IWAYAN GETAS,M.Sc Ariwidiani Ersandhi Resnhaleksmana I Gusti Ayu Nyoman Danuyanti Sofiyan Dwi Arfi