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All Journal Tropical Medicine Journal Jurnal Kesehatan Prima Jurnal Analis Medika Biosains (JAMBS) Anakes: Jurnal Ilmiah Analis Kesehatan

I Gusti Ayu Nyoman Danuyanti

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Author-ID : 249660

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Articles

ZOONOTIC HOOKWORM THAT POTENTIALLY CAUSES CREEPING ERUPTION IN CAKRANEGARA Resnhaleksmana, Ersandhi; Ariami, Pancawati; Danuyanti, I Gusti Ayu Nyoman
Jurnal Analis Medika Biosains (JAMBS) Vol 1, No 1 (2014): Jurnal Analis Medika Bio Sains
Publisher : Jurusan Analis Kesehatan, Poltekkes Kemenkes Mataram

AbstractMaintenance of animals like dogs in Cakranegara not matched with a good understanding of the spread of the disease. That Causes increase the risk of disease transmission from animal to animal or from animal to human. A wild dog that lives at risk of disease transmission is higher than the breed. One of the animal diseases that can be transmitted to humans (zoonoses) is a Hookworm. which can cause creeping eruption. This study was an observational descriptive, with the aim to determine the prevalence of Zoonotic Hookworm in dogs that could potentially cause creeping eruption in Cakranegara. Sampling was purposive sampling as many as 30 samples with wet paint (direct) and Berrman methods. Results, the prevalence of zoonotic hook worm was 14 of 30 samples of dog feces (46%).Keywords: Prevalence, Zoonotic Hookworm, Creeping eruption.

PREVALENCE OF CANDIDIASIS BASED ON THE TEST RESULT OF WOMEN’S SEDIMENTS AND URINE CULTURE WHO SUFFER DIABETES MELLITUS AT PUSKESMAS IN WEST LOMBOK REGENCY Danuyanti, I Gusti Ayu Nyoman; Rohmi, Rohmi; Resnhaleksmana, Ersandhi
Jurnal Analis Medika Biosains (JAMBS) Vol 1, No 1 (2014): Jurnal Analis Medika Bio Sains
Publisher : Jurusan Analis Kesehatan, Poltekkes Kemenkes Mataram

AbstractDiabetes mellitus is a predisposing factor for the incidence of genital candidiasis. Women with diabetes mellitus have extra sugar in the vaginal wall, so that the urine of women with diabetes mellitus are likely to be found Candida albicans. The cause of candidiasis related to the way we take care of the reproductive organs, which means he12alth status is influenced by behavioral factors. The purpose of this study to determine patterns of hygiene and sanitation women with diabetes mellitus in the case of thrush, so it can be a known cause of candidiasis due to excess glucose in the blood factors or because the behavior of the diabetic patient. The method used analytic observational with the variables measuring cross sectional against 76 respondents drawn from the health center and Kediri Narmada, West Lombok district with 21.05% prevalence of candidiasis. Examination of candidiasis infection obtained based on the examination of urine sediment and culture of women with DM. Overall women with diabetes could be at risk or infected with Candida albicans even though the disease are predisposing factors of candidiasis vaginitis.Keywords: Candidiasis, Urine sediment, Urine culture, Diabetes mellitus

Distal Renal Tubular Acidosis (dRTA) Among Southeast Asian Ovalocytosis (SAO) Patients in Malaria Endemic Area of Sekotong, Lombok Island I Gusti Ayu Nyoman Danuyanti; Tasmini -; Ahmad Hamim Sadewa
Tropical Medicine Journal Vol 1, No 1 (2011): Tropical Medicine Journal
Publisher : Pusat Kedokteran Tropis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/tmj.4568

Introduction: Southeast Asian Ovalocytosis (SAO) is caused by 27 bp deletion of the band 3 protein gene in erythrocyte membrane and characterized by oval erythrocyte. The erythroid band 3 (AE1) gene isexpressed not only in erythrocyte membranes but also in the cell membrane of α-collecting renal tubular functions in the secretion of acid in renal tubules and HCO3 -/Cl- anion exchange. An alteration of the band 3 (AE1) gene functions in cell of α-collecting renal tubules reduces HCO3-/Cl- ion exchange resulting in decreased secretion of H+ ions and disturbances in the process of pickling urine as an indicator of distal renal tubular acidosis (dRTA).Objectives: To determine the occurrence of dRTA among Southeast Asian Ovalocytosis (SAO) patients in malaria endemic area of Sekotong, Lombok Island by analyzing expression of erythroid band 3 (AE1) gene.Methods: Ovalocytosis degree determined by oval erythrocytes morphology of 20%-100% in blood film. The 27 bp deletion of band 3 (AE1) gene was analyzed by polymerase chain reaction (PCR). An indicators of the dRTA was determined the pH of urine, levels of bicarbonate (HCO3-), potassium (K+) and chloride (Cl-) in the blood.Results: The degree of ovalocytosis more than 50% was found in 35,7% individuals and below 50% was found in 64,3% individuals. Percentage of 27 bp deletion of band 3 (AE1) gene among subject of ovalocytosispatients was 35,7% (n = 28) and frequency of the dRTA among SAO patients was 20% (n = 10). Individuals with SAO do not generally have dRTA. The presence of the two conditions in the same individuals suggests that there may be a common underlying molecular defect or genetic basis for SAO and dRTA.Conclusion: There is a relationship between the 27 bp deletion protein band 3 (AE1) gene with distal renal tubular acidosis (dRTA) among Southeast Asian Ovalocytosis (SAO) patients in Sekotong, Lombok Island, even the percentage is low.Keywords: distal renal tubular acidosis, Southeast Asian Ovalocytosis, Sekotong, (Lombok Island)

THE USE OF BLACK SOYBEAN (Glycine max L) EXTRACT AGAINST THE ACTIVITY OF LIVER ENZYMES (AST - ALT) AND ANTIOXIDANT SUPEROXIDE DISMUSTASE (SOD) OF WHITE RAT I Gusti Ayu Nyoman Danuyanti; Ersandhi Resnhaleksmana
Jurnal Kesehatan Prima Vol 12, No 1 (2018): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Abstract: Strenuous physical activity can increase the activity of enzymes AST (aspartate aminotransaminase) and ALT (alanine aminotransaminase) in the blood as a sign of hepatic dysfunction caused by oxidative stress as a result. Excessive free radicals that damage macromolecules in cells. The supplementation of black soybean (Glycine max L) contains anthocyanin as an antioxidant is expected to reduce the formation of free radicals thus the activity of liver enzymes and the levels of SOD enzymes as intracellular antioxidant can be maintained. The purpose of this study was to determine the effect of using extracts of black soybean (Glycine max L) on the activity of liver enzymes (AST-ALT) and the antioxidant superoxide dismutase (SOD) of white rats that were given a maximum of physical activity. The research was control group post test design in vivo that used black soya extract treatment given to white rats (Rattus norvegicus) Wistar strain given maximum physical activity. The results indicated black soybean extract 40% was the most powerful retaining the activity of liver enzymes and blood levels of antioxidants SOD. The conclusion is there is an effect of black soybean extract against the activity of liver enzymes (AST-ALT) in rats given maximal activity, whereas SOD enzymes can inhibit the decline of SOD enzyme level to 37.8% but statistically there is no significant influence.Keywords: AST-ALT enzymes; antioxidants SOD; Soybean black; Physical activity maximum.

STUDI TOXOPLASMOSIS PADA PENDERITA SCHIZOPHRENIA DI RUMAH SAKIT JIWA PROVINSI NTB Ersandhi Resnhaleksmana; Nursardjan Nursardjan; I Gusti Ayu Nyoman Danuyanti
Jurnal Kesehatan Prima Vol 8, No 1 (2014): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Abstract: Toxoplasmosis, a disease caused by Toxoplasma gondii, a parasite of humans and animals scattered throughout the world. Infection T. gondii into the body of most real place in the reticuloendothelial tissues and the brain with symptoms of central nervous system often leave residual symptoms, such as mental and motor retardation. This phenomenon often occurs in people with schizophrenia. This study aims to determine the toxoplasmosis in patients with schizophrenia in Rumah sakit jiwa Provinsi NTB. The Methods of This study used an observational analytic design with cross-sectional design to determine the percentage of toxoplasmosis, by examination of the ELISA for determination of IgG T. gondidi serum samples of patients with schizophrenia at Rumah Sakit Jiwa Provinsi NTB. The research was conducted in July-November 2011, with a total sample size is 42 people. The idependent variabel is Toxoplasmosis and the dependent variabel is patient with schizophrenia.There is a percentage of toxoplasmosis in patients with schizophrenia was 54.8% (23 people) with higher levels of IgG T. gondii highest was 300 UI / ml. From the results of this study indicate the presence of infection T. gondii in patients with schizophrenia at Rumah Sakit jiwa Provinsi NTB.

HUBUNGAN KADAR NITRIT OKSIDA (NO) DALAM DARAH TERHADAP RESIKO KEJADIAN DIABETES MELLITUS TIPE 2 DENGAN HIPERTENSI DI RSUP NTB I Gusti Ayu Nyoman Danuyanti; Erna Kristinawati; Ersandhi Resnhaleksmana
Jurnal Kesehatan Prima Vol 8, No 1 (2014): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Abstract: Diabetes Mellitus (DM) is a group of metabolic diseases with characteristic hyperglycemia that occurs due to abnormalities in insulin secretion, insulin action or both. Pathophysiology of type 2 diabetes mellitus are very complex with involving a variety of factors, including nutrition, obesity, sedentary lifestyle, and lack of physical activity, and genetik. The prolonged of condition hyperglycemia causes endothelial cell dysfunction resulting in decreased production of various compounds that are antithrombotic and vasodilating include nitric oxide ( NO). The purpose of this study was to determine the relationship between levels of nitric oxide (NO) in the blood against the risk of incident type 2 diabetes mellitus with hypertension at the RSUP NTB. This study uses a case-control design, with a sample size of 30 people with type 2 diabetes with hypertension as the case group and 30 patients without hypertension, diabetes mellitus type as the control group. The total sample is 60 people. Dependent variable in this study is the levels of NO in the blood while the independent variables of type 2 DM patients with hypertension. Determination of levels of nitric oxide (NO) in the blood using spectrophotometric methods. Correlation test is used to determine the relationship between levels of nitric oxide (NO) in blood with the blood pressure while Chi-square test used to determine the relationship of NO levels on the risk of incident type 2 diabetes with hypertension. The results showed average mean levels of NO in patients with type 2 diabetes with hypertension was lower than 0.54 μM with type 2 DM patients without hypertension is 1.32 μM. The results of correlation test levels of NO in the blood and blood pressure showed p-value = 0.000 (<α 0.05) and there is a strong relationship with a correlation coefficient value of 0.749 for systolic blood pressure and 0.694 for diastolic. Analysis of the relationship of NO levels in the blood against the risk of incident type 2 diabetes with hypertension show the value of p = 0.000. The overall from the can be concluded There is a relationship between the amount of nitric oxide (NO) in the blood against the risk of incident type 2 diabetes mellitus with hypertension in the RSUP NTB.

SENYAWA PENGKUPLING α-NAFTHILAMIN UNTUK VALIDASI METODE SPEKTROFOTOMETRI PENENTUAN NITRIT (〖〖NO〗_2〗^-) DI DALAM AIR Maruni Wiwin Diarti; I Gusti Ayu Nyoman Danuyanti; I Gede Billy Sumantri
Jurnal Kesehatan Prima Vol 9, No 1 (2015): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Abstract: Validation of analytical methods need to be conducted to determine the feasibility of the method when the method is newly developed or modified. Determination of nitrite in water-based Cupling diazotized reaction has been developed in various fields. Many modifications have been carried out primarily in the selection of the source of the diazonium salt compound or compounds that can cupling. The this study was to determine the validity of the determination of nitrite in water by spectrophotometric method cupling compound α-nafthilamin. This study is a pre-experiments with experimental units and large units based guidelines experimental validation of analytical methods. The results show the value of 0.995 linearity, limit of detection (LOD) 0.039 ppm, 0.882 sensitivity, precision 1.38%, and 100.37% accuracy rate. The conclusion of this study is the method of spectrophotometric determination of nitrite in water using compound α-nafthilamin cupling valid for determining the concentration of nitrite in the water with a minimum detection limit of 0.039 ppm.

Pemanfaatan Teh Daun Sirsak (Annona muricata L.) Terhadap Kadar Kolesterol Total, Trigliserida Dan Glukosa Darah Pada Pasien Diabetes Mellitus Dengan Hipertensi Utari Rizki Rahmayanti; I Gusti Ayu Nyoman Danuyanti; Siti Zaetun
Anakes : Jurnal Ilmiah Analis Kesehatan Vol 8, No 2 (2022): Anakes: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v8i2.535

AbstrakDiabetes mellitus (DM) merupakan penyakit metabolik dengan karakteristik hiperglikemia dan hiperlipidemia. Yang dimana merupakan faktor resiko terjadinya hipertensi. Makanan yang dapat menurunkan kolesterol, trigliserida dan glukosa darah adalah bahan makanan yang mengandung zat flavonoid dan saponin yang terdapat dalam teh daun sirsak. Artikel ini bertujuan untuk mengetahui manfaat pemberian teh daun sirsak (Annona muricata L.) terhadap kadar kolesterol total, trigliserida dan glukosa darah pada pasien diabetes melitus dengan hipertensi. Desain penelitian ini adalah kuasi eksperimental menggunakan One group pretest-posttest dengan jumlah sampel 10 orang responden. Data yang dikumpulkan berupa data hasil pemeriksaan kadar kolesterol total, trigliserida dan glukosa darah sebelum dan setelah pemberian teh daun sirsak. Rerata hasil pemeriksaan kadar kolesterol total setelah pemberian teh daun sirsak adalah 141.8 mg/dL menurun dibandingkan sebelum pemberian yaitu 182,1 mg/dL (penurunan sebesar 40,3 mg/dL atau 22,13%). Rerata hasil pemeriksaan trigliserida setelah pemberian adalah 172,1 mg/dL menurun dibandingkan sebelum pemberian yaitu 647 mg/dL (penurunan sebesar 474,9 mg/dL atau 73,40%) dan rerata hasil pemeriksaan glukosa setelah pemberian adalah 209,1 mg/dL menurun dibandingkan sebelum yaitu 341,1 mg/dL (Penurunan sebesar 132 mg/dL atau 38,69%). Sehingga pemberian teh daun sirsak selama 30 hari dapat menurunkan kadar kolesterol total, trigliserida dan glukosa darah pada pasien diabetes melitus dengan hipertensi.Kata kunci : Diabetes mellitus, glukosa darah, kolesterol total, teh daun sirsak, trigliserida

Co-Authors Ahmad Hamim Sadewa Erna Kristinawati Ersandhi Resnhaleksmana I Gede Billy Sumantri I Komang Agusjaya Mataram, I Komang Agusjaya Maruni Wiwin Diarti Ni Putu Agustini Nursardjan Nursardjan Pancawati Ariami, Pancawati Pauzi, Iswari Resnhaleksmana, Ersandhi Resnhaleksmana, Ersandhi Rohmi, Rohmi Siti Zaetun Tasmini - Utari Rizki Rahmayanti Yuli Laraeni, Yuli

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