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Journal : Jurnal Insan Farmasi Indonesia

UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETANOL DAN KLOROFORM BUAH SENGGANI (Melastoma malabathricum L.) DENGAN MENGGUNAKAN METODE PENANGKAP RADIKAL BEBAS DPPH (2,2-Diphenyl-1-picrilhidrazil) Dian Kartikasari; Ika Ristia Rahman; Syarifah Nurhayati
Jurnal Insan Farmasi Indonesia Vol 1 No 1 (2018)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Buah senggani diketahui mengandung senyawa antioksidan, masalah yang dihadapi adalah senyawa aktif yang terkandung dan seberapa besar aktivitas senyawa antioksidan yang terkandung didalam buah senggani. Untuk itu dilakukan uji fitokimia dan uji aktivitas antioksidan pada fraksi etanol dan kloroform buah senggani dengan metode penangkap radikal bebas DPPH dengan menggunakan pembanding vitamin C. Hasil uji fitokimia pada fraksi etanol mengandung senyawa metabolit sekunder golongan alkaloid, flavonoid triterpenoid dan steroid serta tanin, sedangkan pada fraksi kloroform mengandung senyawa metabolit sekunder golongan alkaloid, flavonoid dan steroid. Hasil uji aktivitas antioksidan fraksi etanol buah senggani di dapat nilai IC50 sebesar 2,31 ppm dan fraksi kloroform buah senggani di dapat sebesar 1,12 ppm. Dari hasil tersebut diketahui buah senggani memiliki aktivitas antioksidan yang sangat kuat.
KARAKTERISTIK DAN NILAI SUN PROTECTING FACTOR (SPF) KITOSAN DARI TULANG SOTONG (Sephia officinalis) Ika Ristia Rahman; Athiah Masykuroh
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.539

Abstract

Cuttlefish (sepia officinalis) have internal shells commonly called cuttlebones which produce more chitin than shrimp shells and crab skins. The purpose of this study was to determine the characteristics of chitosan from cuttlebone including the degree of deacetylation, water content, solubility, organoleptic test (color, odor, texture) as well as testing the value of chitosan protecting the sun protection factor. Chitosan is made in 3 stages, namely deproteination, demineralization, and deacetylation. Deproteination with 4% NaOH at 100 ° C for 60 minutes. Demineralization at room temperature using 1M HCl solution for 120 minutes. Deacetylation using 50% NaOH concentration at 100 ° C for 60 minutes. Chitosan characterization includes the degree of deacetylation, moisture content, solubility, organoleptic test (color, odor, texture). Testing the value of sun protection factor using a UV-VIS spectrophotometer read at wavelengths from 290 to 320 nm. Characteristics of chitosan produced according to chitosan standards used in industry with a deacetylation rate of 71%, yield 31%, moisture content of 0.93%, soluble in acetic acid2% solution, white odorless and powdery. Chitosan with a concentration of 3% gives the value of sun protecting factor 9 as a potential sunscreen that provides maximum protection power.
POTENSI SUSPENSI CANGKANG TELUR AYAM (Gallus domesticus) SEBAGAI ANTASIDA Dian kartikasari; Ika Ristia Rahman; Hairunisa Hairunisa; Abduh Ridha
Jurnal Insan Farmasi Indonesia Vol 4 No 2 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i2.704

Abstract

Kalsium karbonat merupakan kadungan utama pada cangkang telur. Kalsium karbonat dibidang farmasi dapat digunakan sebagai antasida. Sediaan suspensi lebih cepat di serap dibandingkan dengan sediaan tablet kunyah. Penelitian ini bertujuan untuk mengetahui apakah suspensi cangkang telur ayam mampu bekerja sebagai antasida, dan untuk mengetahui konsentrasi efektif. Metode penelitian yang dilakukan adalah Kapasitas Penetralan Asam (KPA), dimana asam lambung disimulasikan menggunakan HCL. Sediaan suspensi yang dibuat dilakukan evaluasi fisik meliputi uji oraganoleptis, uji pH, uji homogenitas, uji viskositas, uji bobot jenis, uji sedimentasi. Hasil organoleptis yang didapat yaitu suspensi berwarna putih kekuningan berbau khas, berbentuk cair dan memiliki rasa yang manis. Sediaan suspensi homogen, pH suspensi formula 1, 2, dan 3 berturut turut adalah 7,37; 7,50 dan 7,37. Nilai viskositas suspensi formula 1,2, dan 3 berturut turut yaitu 10 cp; 14 cp dan 25 cp. Bobot jenis pada suspensi pada formula 1, 2, dan 3 berturut turut yaitu 1,12 g/ml; 1,14 g/ml dan 1,17 g/ml. Hasil uji sedimentasi menunjukkan terjadi sedimentasi pada formula 3. Nilai KPA formula 1,2 dan 3 berturut turut yaitu 9,92 mEq, 9,87 mEq, dan 10,08 mEq
FORMULASI LOTION EKSTRAK TERPURIFIKASI DAUN KENIKIR (Cosmos caudatus Kunth). Erwan Kurnianto; Ika Ristia Rahman; Dian Kartikasari; Hairunnisa Hairunnisa
Jurnal Insan Farmasi Indonesia Vol 4 No 2 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i2.830

Abstract

Kenikir leaves (Cosmos caudatus Kunth) is a plant that is used as a vegetable and ornamental plant. Kenikirleaves contain flavonoid, phenol, diterpene, and ascorbic acid phytochemicals. The phytochemical content of kenikir leaves has antioxidant activity. The preparation widely used in applying antioxidants is lotion because of its easy use. This study aims to formulate a lotion from the purified extract of kenikir leaves by varying the extract 0.1%, 0.25% and 0.5%. The lotion base used was VCO, Tween 80, PEG 400, Aquadest. The physical characteristics evaluated were organoleptic, homogeneity, pH, spreadability, and emulsion type. From the results test, purified extract lotion of kenikir leaves gave a green color, characteristic smell of the extract, homogeneous, pH value according to lotion requirements, dispersion according to the standard range of 5-7cm, emulsion type of lotion oil in water.
UJI FITOKIMIA PADA DAUN KESUM (Polygonum minus Huds.) DARI KALIMANTAN BARAT Dian Kartikasari; Ika Ristia Rahman; Abduh Ridha
Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i1.912

Abstract

Kesum leaves are one of the plants that are widely available in West Kalimantan and are used by the community as vegetables or cooking spices. Research on the chemical content of kesum leaves has been carried out by several researchers, but research on whether there are differences in the chemical content obtained from the extraction with several types of solvents in kesum leaves has not been carried out. Therefore, in this study, the chemical content of kesum leaves will be tested. The method used is to test the presence of chemical compounds by phytochemical screening on several kesum leaf extracts using different solvents, namely 70% ethanol, 50% ethanol, 96% ethanol and methanol. The observations obtained were then analyzed descriptively and presented in tabular form. The results of the phytochemical screening test showed that the kesum leaf extracted in 70% ethanol, 50% ethanol, 96% ethanol, and methanol solvent contained phenols, flavonoids, saponins, and tannins. Moreover, extract of ethanol 70% and ethanol 50%, also contain terpenoids amd alkaloids, which were not detected on ethanol 96% and methanol extract.
UJI FITOKIMIA PADA DAUN KESUM (Polygonum minus Huds.) DARI KALIMANTAN BARAT Dian Kartikasari; Ika Ristia Rahman; Abduh Ridha
Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i1.912

Abstract

Kesum leaves are one of the plants that are widely available in West Kalimantan and are used by the community as vegetables or cooking spices. Research on the chemical content of kesum leaves has been carried out by several researchers, but research on whether there are differences in the chemical content obtained from the extraction with several types of solvents in kesum leaves has not been carried out. Therefore, in this study, the chemical content of kesum leaves will be tested. The method used is to test the presence of chemical compounds by phytochemical screening on several kesum leaf extracts using different solvents, namely 70% ethanol, 50% ethanol, 96% ethanol and methanol. The observations obtained were then analyzed descriptively and presented in tabular form. The results of the phytochemical screening test showed that the kesum leaf extracted in 70% ethanol, 50% ethanol, 96% ethanol, and methanol solvent contained phenols, flavonoids, saponins, and tannins. Moreover, extract of ethanol 70% and ethanol 50%, also contain terpenoids amd alkaloids, which were not detected on ethanol 96% and methanol extract.