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Penentuan Kadar Enzim Kolinesterase pada Petani Pengguna Pestisida Organofosfat Berdasarkan Frekuensi Penyemprotan Devi Yoga Saputra; Purwati Purwati; Tri Harningsih
Jurnal Farmasi (Journal of Pharmacy) Vol 9, No 2 (2020): Oktober
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v9i2.106

Pestisida secara umum diartikan sebagai bahan kimia beracun yang digunakan untuk mengendalikan hama yang merugikan manusia. Pestisida telah digunakan untuk meningkatkan produksi pertanian, perkebunan dan pemberantasan vektor penyakit. Frekuensi penyemprotan dan tingginya volume penggunaan pestisida menunjukkan peran penting pestisida tersebut dalam produksi tanaman, pestisida tersebut tidak dapat dilepaskan dari penanaman pertanian. Kebanyakan petani menyemprot sendiri dan memiliki alat penyemprot sendiri sehingga mereka memiliki fleksibilitas untuk menyemprot. Penanam sayuran memiliki risiko keracunan pestisida yang tinggi. Penelitian ini menggunakan metode studi literatur. Pengumpulan data menggunakan data sekunder yang diambil dari jurnal ilmiah dan karya ilmiah rentan 10 tahun terakhir. Analisis data menggunakan analisis deskriptif. Enzim kolinesterase merupakan enzim yang terdapat pada cairan seluloid. Enzim ini berfungsi menghentikan kerja asetilkolin dengan cara menghidrolisis menjadi kolin dan asam asetat. Asetilkolin adalah saraf pengantar yang terletak di seluruh sistem saraf pusat (SSP), saraf otonom (simpatis dan parasimatik), dan sistem saraf somatik. Hasil penelitian menyatakan bahwa 4 jurnal menyatakan ada hubungan antara frekuensi penyemprotan dengan kadar enzim cholinesterase, sedangkan 2 jurnal menyatakan tidak ada hubungan. Frekuensi penyemprotan berpengaruh terhadap penurunan kadar enzim kolinesterase pada petani pengguna pestisida organofosfat.

Description of Carboxyhemoglobin (COHb) Levels in Parkir Attendants Based on Working Period Around Bejen Market Tri Harningsih; Indah Tri Susilowati; Purwati Purwati; Definingsih Yuliastuti
Indonesian Journal of Global Health Research Vol 4 No 2 (2022): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Carbon monoxide is the largest contributor to air pollution. The source of carbon monoxide contamination comes from the smoke exhaust of motor vehicles. This research was to find out the description of carboxyhemoglobin levels in parking attendants based on working period around Bejen Market. This research method uses descriptive research. The sampling technique used is quota sampling. The research subjects were 8 parking attendants around Bejen market. Examination of carboxyhemoglobin levels using UV-Vis spectrophotometer. The results showed that in the blood of all respondents there was an increase in carboxyhemoglobin levels. The sample with code A1 has a level of 5,56%; sample A2 = 5,20%; sample A3 = 5,40%; sample A4 = 5,56%; sample A5 = 6,30%; sample A6 = 5,66%; sample A7 = 5,80%; and sample A8 = 6,36%. The level of carboxyhemoglobin in parking attendants around Bejen market exceeded the normal limit of >3,5% by the Regulation of the Minister Health Republic Indonesia Number 70 of 2016.

The Reduction Of Water Level In Used Cooking Oil Using Bagasse Charcoal (Saccharum officinarum) Kharisma Islamia Nanda Giovani; Purwati Purwati
Jurnal Farmasi (Journal of Pharmacy) Vol 11, No 1 (2022)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v11i1.168

Recycling technology processes used cooking oil into reusable oil using bagasse as an absorbent material, to determinate the decrease in water content in used cooking oil using bagasse chacoal. the reseach method is experimental. The sample used is used cooking oil. Water level before the addition of bagasse charcoal was 0,3%. This results after the additional of bagasse charchoal with variation of immersion time 1x24 hours, 2x24 hours and 3x24 hours was 0,1%, 0,03%, and 0,02%.There is reducing in water level after soaking using bagasse charcoal. Water level from used cooking oil more smaller after the addition of soaking time by bagasse charcoal.

Description of the Event of Irritant Contact Dermatitis in Employees of the Home Industry Batik Dewi Saroh; Purwati Purwati; Tri Harningsih
Indonesian Journal of Global Health Research Vol 4 No 3 (2022): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Batik is one of Indonesian culture which has high artistic value. The dyes used in the batik industry can come from natural dyes and synthetic dyes. Synthetic dyes contain hazardous chemical compounds in the form of heavy metals. Heavy metal compounds can cause cancer in living things. Contact with chemicals, such as workers in the batik industry can cause various skin disorders. One of the skin disorders that occurs due to exposure to chemicals is contact dermatitis. Based on research data from 21 employees of the coloring division in the batik home industry, the prevalence of irritant contact dermatitis was 33.33% (7 people) with the most characteristic age being 40-70 years, working duration >5 years, exposure contact duration 0-3 hours. / day, the most common symptoms are itching that occurs on the palms of the hands, backs of hands, forearms, between the fingers, and the backs of the feet. Respondents who had a history of atopic dermatitis were only 9.52% (2 people), and for exposure to chemicals other than batik dyes only 19.05% (4 people). Other chemicals that trigger contact dermatitis are detergents and fragrances. From the incidence of irritant contact dermatitis to employees of the coloring department in the batik home industry, more employees choose to be left alone than treated because the symptoms that appear are mild and do not interfere with work activities.

Pengaruh Lama Penyemprotan terhadap Kadar Enzim Cholinesterase pada Petani Pengguna Pestisida Organofosfat: The Effect of Spraying Time on Cholinesterase Enzyme Levels in Farmers that Used Organophosphate Anggi Parasitekta; Purwati Purwati; Tri Harningsih
Jurnal Surya Medika (JSM) Vol. 8 No. 3 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i3.3296

Pesticides can increase productivity in agriculture. Excessive and uncontrolled use of pesticides can pose a risk of poisoning farmers. Decreased levels of cholinesterase enzymes characterize poisoning. The duration of spraying is an indicator that can affect the levels of the cholinesterase enzyme. This study aimed to determine how long spraying affects cholinesterase enzyme levels in farmers who use organophosphate pesticides. Examination of cholinesterase using the enzymatic cholinesterase test method. The most commonly used sample is a sample of serum rather than red blood cells. The study's results stated that there was a relationship between the duration of spraying and the levels of the cholinesterase enzyme. The duration of spraying in a day gives an idea of the intensity of pesticide exposure. The longer the spraying time, the higher the pesticide exposure and the decreased levels of the cholinesterase enzyme in the blood.

Gambaran Kadar Karboksihemoglobin (COHb) pada Mahasiswa Pengguna Sepeda Motor Sinta Nuriyah; Purwati Purwati; Tri Harningsih
Jurnal Farmasetis Vol 11 No 1 (2022): Jurnal Farmasetis: Mei 2022
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (142.498 KB)

Carbon monoxide (CO) is a colorless, odorless and tasteless gas. Exposure to high concentrations of carbon monoxide gas during continuous exposure can cause an increase in blood COHb levels. The purpose of this study was to determine the level of carboxyhemoglobin based on the length of exposure in students. The method of examination uses the Conway diffusion cell. The samples used were 7 samples from students at one of the universities in Sukoharjo. The sampling technique uses quota sampling. Data is collected started by charging informan consent as evidence samples probandus agreed in this research. It is filling out the questionnaire and obtained 7 sample qualifies as probandus in this research. Blood sampling on the probandus was carried out on the same day. COHb levels in the samples were examined sequentially as results: 0,43%; 0,41%; 0,32%; 0,34%; 0,47%; 0,48%; and 0,46%. All samples examined had COHb levels below the standard threshold of the PERMENKES RI No. 70 of 2016 which was not more than 3,5%.

Description of Carboxyhemoglobin (COHb) Levels in Parkir Attendants Based on Working Period Around Bejen Market Tri Harningsih; Indah Tri Susilowati; Purwati Purwati; Definingsih Yuliastuti
Indonesian Journal of Global Health Research Vol 4 No 2 (2022): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Carbon monoxide is the largest contributor to air pollution. The source of carbon monoxide contamination comes from the smoke exhaust of motor vehicles. This research was to find out the description of carboxyhemoglobin levels in parking attendants based on working period around Bejen Market. This research method uses descriptive research. The sampling technique used is quota sampling. The research subjects were 8 parking attendants around Bejen market. Examination of carboxyhemoglobin levels using UV-Vis spectrophotometer. The results showed that in the blood of all respondents there was an increase in carboxyhemoglobin levels. The sample with code A1 has a level of 5,56%; sample A2 = 5,20%; sample A3 = 5,40%; sample A4 = 5,56%; sample A5 = 6,30%; sample A6 = 5,66%; sample A7 = 5,80%; and sample A8 = 6,36%. The level of carboxyhemoglobin in parking attendants around Bejen market exceeded the normal limit of >3,5% by the Regulation of the Minister Health Republic Indonesia Number 70 of 2016.

Description of the Event of Irritant Contact Dermatitis in Employees of the Home Industry Batik Dewi Saroh; Purwati Purwati; Tri Harningsih
Indonesian Journal of Global Health Research Vol 4 No 3 (2022): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Batik is one of Indonesian culture which has high artistic value. The dyes used in the batik industry can come from natural dyes and synthetic dyes. Synthetic dyes contain hazardous chemical compounds in the form of heavy metals. Heavy metal compounds can cause cancer in living things. Contact with chemicals, such as workers in the batik industry can cause various skin disorders. One of the skin disorders that occurs due to exposure to chemicals is contact dermatitis. Based on research data from 21 employees of the coloring division in the batik home industry, the prevalence of irritant contact dermatitis was 33.33% (7 people) with the most characteristic age being 40-70 years, working duration >5 years, exposure contact duration 0-3 hours. / day, the most common symptoms are itching that occurs on the palms of the hands, backs of hands, forearms, between the fingers, and the backs of the feet. Respondents who had a history of atopic dermatitis were only 9.52% (2 people), and for exposure to chemicals other than batik dyes only 19.05% (4 people). Other chemicals that trigger contact dermatitis are detergents and fragrances. From the incidence of irritant contact dermatitis to employees of the coloring department in the batik home industry, more employees choose to be left alone than treated because the symptoms that appear are mild and do not interfere with work activities.

Gambaran Kadar Timbal pada Pekerja Pewarna Batik di Laweyan Purwati Purwati; Tri Harningsih; Dewi Saroh
Jurnal Farmasetis Vol 12 No 2 (2023): Jurnal Farmasetis: Mei 2023
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32583/far.v12i2.1090

Kampung Batik Laweyan merupakan suatu kawasan permukiman yang unik, spesifik, dan bersejarah, yaitu menjadi kampung yang terkenal dengan kerajinan batik. Proses membatik dilakukan melalui beberapa tahap, yaitu tahap persiapan, tahap pemolaan, pemalaman, selanjutnya pewarnaan celup, pelorodan atau penghilangan lilin batik dan yang terakhir adalah finishing. Proses perwarnaan batik menggunakan pewarna alami dan pewarna sintetik. Kandungan logam berat yaitu timbal pada pewarna batik sintetik memberikan dampak resiko kesehatan bagi para pekerja yang terpapar. Tujuan penelitian ini untuk mengetahui gambaran kadar timbal pada pekerja pewarna batik di Laweyan. Penelitian dilakukan secara deskriptif, dengan jumlah responden sebanyak 21 sampel. Sampel darah diambil sebanyak 3 ml menggunakan vacuum tube EDTA. Selanjutnya sampel dimasukkan dalam ice box yang sudah dilengkapi ice gel untuk dibawa ke Laboratorium Hematologi STIKES Nasional guna dilakukan pemeriksaan profil hematologi dengan menggunakan hematology analyzer. Sampel darah selanjutnya dikirim ke Balai Laboratorium Kesehatan dan Kalibrasi Yogyakarta untuk pemeriksaan kadar timbal menggunakan spektrofotometer serapan atom. Pembacaan hasil diperoleh sebanyak 6 sampel memiliki kadar timbal lebih dari 10 µL/dL; 10 sampel memiliki kadar timbal kisaran 1-10 µL/dL dan 5 sampel memiliki kadar timbal dibawah 1 µL/dL. Kadar timbal dalam darah melebihi 10 µL/dL terindikasi adanya kemungkinan keracunan timbal.

Overview of Blood Lead Levels in Refueling Operator Workers on Veteran Street Surakarta Based on Health Complaints Santika Fatimah Zahro; Purwati Purwati
Indonesian Journal of Global Health Research Vol 5 No 4 (2023): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v5i4.2353

Lead is a heavy metal that is naturally available in nature. As technology develops, many people use lead in various fields, thereby increasing the presence of lead in the environment, one of the uses of lead is in fuel. If humans are exposed to lead continuously, it will accumulate and cause health problems. One job that is vulnerable to lead exposure is fuel filling operators. The aim of this study was to measure the amount of lead in the blood of fueling operators and observe health problems that arise. Descriptive research method describes a particular observation that occurred. Researchers collect information on various events and observations to use as a starting point for analysis. Sampling used the quota sampling technique, namely determining the sample size from the population of refueling workers by looking at the specified criteria and the number of samples taken was 10 probands. Analysis of lead levels in the blood uses an atomic absorption spectrophotometer and the results in the form of lead levels in the blood are analyzed descriptively and presented in table form and narrated by looking at the results of the questionnaire that has been obtained. The results obtained were that the lowest level of lead in the blood of a gas station operator was 0.04 µg/dL and the highest lead level was 1.35 µg/dL. Description of blood lead levels of fuel operators on Jalan Veteran Surakarta do not exceed the limit, namely less than 10 µg/dL according to the Center for Disease Control and Prevention (CDC), with the most frequently felt symptom being work fatigue.

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