Articles
<![CDATA[Ancaman Zoonosis : Infeksi Plasmodium knowlesi pada Manusia ]]>
<![CDATA[Dewi Saroh]]>;
<![CDATA[Dwi Haryatmi]]>
<![CDATA[ Jurnal Farmasi (Journal of Pharmacy) Vol 8, No 1 (2019): Oktober ]]>
Publisher : <![CDATA[SEKOLAH TINGGI ILMU KESEHATAN NASIONAL ]]>
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DOI: 10.37013/jf.v1i8.73
<![CDATA[Plasmodium knowlesi merupakan salah satu protozoa darah yang dapat menyebabkan penyakit malaria. P. knowlesi pada awalnya hanya menginfeksi monyet ekor panjang, namun saat ini dapat menyebabkan zoonosis dan menginfeksi manusia. P. knowlesi dapat menginfeksi tubuh manusia secara tunggal ataupun mix-infection dengan parasit lain. Tulisan ini bertujuan untuk memberikan review terkait morfologi, prevalensi, diagnosis, dan pengobatan dari infeksi P. knowlesi. Hasil dari review didapatkan bahwa diagnosis P. knowlesi dapat ditegakkan dengan pemeriksaan PCR karena diagnosis secara mikroskopis dapat menimbulkan mis-identification sehingga menyebabkan kesalahan dalam diagnosis. Penularan P. knowlesi ke manusia dapat terjadi melalui gigitan nyamuk Anopheles Leucosphyrus Group. Prevalensi P. knowlesi hingga saat ini banyak ditemukan di wilayah Asia Tenggara khususnya di Malaysia. Pengobatan malaria akibat P. knowlesi tanpa komplikasi dapat diberikan dengan terapi ACT atau dengan kombinasi klorokuin dan primakuin.]]>
<![CDATA[HUBUNGAN TITER WIDAL DENGAN JUMLAH LIMFOSIT PADA KASUS DEMAM TIFOID DI WILAYAH KERJA PUSKESMAS SAWOO ]]>
<![CDATA[Yaninda Setyanti Ekasari]]>;
<![CDATA[Dewi Saroh]]>
<![CDATA[ Jurnal Analis Laboratorium Medik Vol 6 No 2 (2021): JURNAL ANALIS LABORATORIUM MEDIK ]]>
Publisher : <![CDATA[UNIVERSITAS SARI MUTIARA INDONESIA ]]>
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DOI: 10.51544/jalm.v6i2.2134
<![CDATA[Typhoid fever is a systemic infection that is still a global problem, especially in Indonesia. This disease is caused by Salmonella bacteria. The Widal test is used to detect antibodies to Salmonella bacteria based on agglutination reactions between bacterial antigens and antibodies called agglutinins. Routine blood tests be used to see the body's defense mechanism against infection. Lymphocytes are produced by bone marrow, the presence of bacterial endotoxin causes inhibition of the formation of lymphocytes, so that in some cases of typhoid fever, low lymphocyte counts are often found. The purpose of this study was to determine the relationship between Widal titer and lymphocyte count in patients with suspected typhoid fever. The Widal test was examined using a microscope to see the agglutination formed, while the number of lymphocytes was calculated using a hematology analyzer. The results of the Widal test with a titer of 1/160 were 63.3% with normal lymphocyte counts and 10% with low lymphocytes. While the titer 1/320 obtained 10% of respondents with normal lymphocyte count and 16.7% with low lymphocyte count. The research design used was analytic observation with the type of cross sectional study. Statistical analysis using Kendall's Tau-b correlation test with SPSS. From the correlation test, the significance value is 0.009, and the correlation coefficient is -0.404**, which means that there is a relationship between the Widal titer and the number of lymphocytes with sufficient closeness.]]>
<![CDATA[BLASTOCYSTIS HOMINIS: PROTOZOA USUS POTENSIAL PENYEBAB DIARE ]]>
<![CDATA[Nova Pramestuti]]>;
<![CDATA[Dewi Saroh]]>
<![CDATA[ Sel Jurnal Penelitian Kesehatan Vol 4 No 1 (2017): SEL Jurnal Penelitian Kesehatan ]]>
Publisher : <![CDATA[Balai Penelitian dan Pengembangan Kesehatan Aceh ]]>
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DOI: 10.22435/sel.v4i1.1409
<![CDATA[Blastocystis hominis merupakan protozoa usus yang sering menyebabkan diare dan manifestasi gastrointestinal seperti nyeri perut, muntah, dan perut kembung. Penularan melalui makanan dan air yang terkontaminasi oleh kista dengan rute oral-fekal. Manifestasi klinis baru timbul ketika sistem imun dalam tubuh menurun. Prevalensi Blastocystis hominis lebih tinggi pada negara berkembang terkait dengan kebersihan diri yang kurang, paparan dari binatang, dan konsumsi air minum yang terkontaminasi parasit. Blastocystis hominis dapat menginfeksi tubuh manusia secara tunggal atau terdapat parasit lain yang juga menginfeksi. Penularan Blastocystis hominis dari manusia ke manusia lain dapat dicegah dengan menjaga kebersihan perorangan, kebersihan fasilitas umum, mencegah kontaminasi feses dalam makanan dan air, mengupas dan mencuci buah dan sayuran mentah. Blastocystis hominis is an intestinal protozoa that causes diarrhea and gastrointestinal manifestations such as abdominal pain, vomiting, and flatulence. Transmission is through food and water contaminated by cysts with faecal–oral route. Clinical manifestations emerge when the body immune system is low. High prevalence of Blastocystis infection has been reported in developing countries associated with poor personal hygiene, animal exposure, and contaminated water consumption with parasite. Human were infected with a single species of parasite (Blastocystis hominis) or multiple infection with other parasite. Transmission of Blastocystis hominis from human to human can be prevented by maintaining individual hygiene; public sanitation; and preventing oro-fecal contamination; peeling and washing raw fruits and vegetables.]]>
<![CDATA[Penanganan Hipertensi Dengan Relaksasi dan Konsumsi Infused Water Buah Okra ]]>
<![CDATA[Noviana Dewi]]>;
<![CDATA[Dewi Saroh]]>
<![CDATA[ JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat) VOL. 5 NOMOR 2 SEPTEMBER 2021 JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat) ]]>
Publisher : <![CDATA[Lembaga Publikasi Ilmiah dan Penerbitan (LPIP) ]]>
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DOI: 10.30595/jppm.v5i2.6797
<![CDATA[Hipertensi merupakan suatu kondisi pada tubuh dimana terjadi kenaikan tekanan darah baik tekanan darah sistolik maupun tekanan diastolik. Seseorang dapat dikatakan mengalami hipertensi apabila tekanan darah sistolik/diastolik yaitu >140/90 mmHg). Hipertensi yang tidak dilakukan pengobatan dengan baik dapat menyebabkan terjadinya resiko komplikasi diantaranya yaitu stroke, jantung coroner, infark miokard, gagal ginjal, ensefalopati, dan kejang. Penanganan hipertensi dapat dilakukan dengan penanganan holistic menggunakan treatment psikologis dan pengobatan herbal. Treatment psikologi dapat dilakukan dengan relaksasi, dimana relaksasi tersebut dapat mengurangi stress yang diakibatkan karena meningkatnya tekanan darah serta ketegangan pada otot-otot di seluruh tubuh. Pengobatan herbal dapat dilakukan dengan mengkonsumsi sayuran yang tinggi vitamin, mineral, dan serat seperti pada okra. Buah okra mengandung 8,5% kalium yang dapat menyumbangkan 8% dari kebutuhan tubuh, dimana kalium juga membantu komunikasi saraf dan otot serta membantu dalam mengendalikan tekanan darah. Pengolahan buah okra sebagai infused water dapat dibuat dengan perbandigan 1 buah okra (13 gram) direndam dalam 100 cc air matang, kemudian didiamkan selama 1-2 jam dan dapat diberikan selama 14 hari berturut-turut (± 200 cc).]]>
<![CDATA[Pengaruh Pemberian Paparan Asap Rokok Kretek Terhadap Kadar Hemoglobin Tikus Putih (Rattus norvegicus) ]]>
<![CDATA[Meutia Sekarmaharani]]>;
<![CDATA[Dewi Saroh]]>
<![CDATA[ Anakes : Jurnal Ilmiah Analis Kesehatan Vol 8, No 1 (2022): Anakes: Jurnal Ilmiah Analis Kesehatan ]]>
Publisher : <![CDATA[Universitas Mohammad Husni Thamrin ]]>
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DOI: 10.37012/anakes.v8i1.679
<![CDATA[Rokok membunuh 88 orang per 100.000 penduduk. sebanyak 33,2% penduduk indonesia yang mengkonsumsi tembakau pada tahun 2018. Terdapat berbagai jenis rokok salah satunya rokok kretek yang mengandung bahan kimia berbahaya yaitu tar nikotin karbonmonoksida dan minyak eugenol. Tujuan penelitian untuk mengetahui kadar hemoglobin pada tikus putih (Rattus norvegicus) yang diberi paparan asap rokok kretek. Penelitian ini adalah quasy-eksperiment pasca-test dengan kelompok eksperimen dan kontrol dengan menggunakan teknik sampling simple random sampling. terdapat empat kelompok yaitu kontrol, paparan asap rokok tiga batang sehari, paparan asap rokok lima batang sehari, paparan asap rokok tujuh batang sehari, paparan dilakukan selama 14 hari tiap kelompok berisi enam ekor tikus. Data dianalisa menggunakan uji Kruskal-Wallis SPSS statistic 21. Didapatkan hasil p value 0,166 lebih besar dari nilai α (0,05). Dapat disimpulkan bahwa tidak terdapat pengaruh paparan asap rokok kretek terhadap kadar hemoglobin tikus putih (Rattus norvegicus). Kata Kunci: Hemoglobin, Asap Rokok, Tikus Putih (Rattus norvegicus)]]>
<![CDATA[Description of the Event of Irritant Contact Dermatitis in Employees of the Home Industry Batik ]]>
<![CDATA[Dewi Saroh]]>;
<![CDATA[Purwati Purwati]]>;
<![CDATA[Tri Harningsih]]>
<![CDATA[ Indonesian Journal of Global Health Research Vol 4 No 3 (2022): Indonesian Journal of Global Health Research ]]>
Publisher : <![CDATA[GLOBAL HEALTH SCIENCE GROUP ]]>
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DOI: 10.37287/ijghr.v4i3.1200
<![CDATA[Batik is one of Indonesian culture which has high artistic value. The dyes used in the batik industry can come from natural dyes and synthetic dyes. Synthetic dyes contain hazardous chemical compounds in the form of heavy metals. Heavy metal compounds can cause cancer in living things. Contact with chemicals, such as workers in the batik industry can cause various skin disorders. One of the skin disorders that occurs due to exposure to chemicals is contact dermatitis. Based on research data from 21 employees of the coloring division in the batik home industry, the prevalence of irritant contact dermatitis was 33.33% (7 people) with the most characteristic age being 40-70 years, working duration >5 years, exposure contact duration 0-3 hours. / day, the most common symptoms are itching that occurs on the palms of the hands, backs of hands, forearms, between the fingers, and the backs of the feet. Respondents who had a history of atopic dermatitis were only 9.52% (2 people), and for exposure to chemicals other than batik dyes only 19.05% (4 people). Other chemicals that trigger contact dermatitis are detergents and fragrances. From the incidence of irritant contact dermatitis to employees of the coloring department in the batik home industry, more employees choose to be left alone than treated because the symptoms that appear are mild and do not interfere with work activities.]]>
<![CDATA[Detection of Gene Alg8 and Alg44 in Clinical Isolates Pseudomonas Aeruginosa using Plymerase Chain Reaction Method ]]>
<![CDATA[Didik Wahyudi]]>;
<![CDATA[Wimpy Wimpy]]>;
<![CDATA[Dewi Saroh]]>
<![CDATA[ Indonesian Journal of Global Health Research Vol 4 No 4 (2022): Indonesian Journal of Global Health Research ]]>
Publisher : <![CDATA[GLOBAL HEALTH SCIENCE GROUP ]]>
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DOI: 10.37287/ijghr.v4i4.1292
<![CDATA[The alg8 and alg44 genes are one of the genes that control alginate production in Pseudomonas aeruginosa bacteria, these genes are one of the main virulence factors causing chronic infections in the human body. Pseudomonas aeruginosa is a bacterium that causes infections in several cases in various parts of the body. The purpose of this study was to detect the presence of alg8 and alg44 genes in several isolates of Pseudomonas aeruginosa from several clinical samples (urine, sputum, and pus) using the Polymerase Chains Reaction method. The study was initiated by characterizing and purification of 6 isolates of Pseudomonas aeruginosa from urine, sputum, and pus samples (2 isolates each), identification of isolates was carried out by biochemical tests. Bacterial DNA isolation was carried out using the DNeasy Blood and Tissue Kit, the results of the isolation were tested by electrophoresis. Six samples of Pseudomonas aeruginosa DNA were tested for the presence of alg8 and alg44 genes by PCR method. The primary design was carried out using the website https://www.ncbi.nlm.nih.gov. The alg8 gene as a whole consists of 1214 nitrogenous bases, the primer used produces an amplicon of 882 bp (72.6%), alg44 gene consists of 818bp, the primer used amplifies 316 bp (36%). alg8 and alg44 genes were found in all isolates of Pseudomonas aeruginosa.]]>
<![CDATA[HUBUNGAN TITER WIDAL DENGAN JUMLAH LIMFOSIT PADA KASUS DEMAM TIFOID DI WILAYAH KERJA PUSKESMAS SAWOO ]]>
<![CDATA[Yaninda Setyanti Ekasari]]>;
<![CDATA[Dewi Saroh]]>
<![CDATA[ Jurnal Analis Laboratorium Medik Vol 6 No 2 (2021): JURNAL ANALIS LABORATORIUM MEDIK ]]>
Publisher : <![CDATA[UNIVERSITAS SARI MUTIARA INDONESIA ]]>
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DOI: 10.51544/jalm.v6i2.2134
<![CDATA[Typhoid fever is a systemic infection that is still a global problem, especially in Indonesia. This disease is caused by Salmonella bacteria. The Widal test is used to detect antibodies to Salmonella bacteria based on agglutination reactions between bacterial antigens and antibodies called agglutinins. Routine blood tests be used to see the body's defense mechanism against infection. Lymphocytes are produced by bone marrow, the presence of bacterial endotoxin causes inhibition of the formation of lymphocytes, so that in some cases of typhoid fever, low lymphocyte counts are often found. The purpose of this study was to determine the relationship between Widal titer and lymphocyte count in patients with suspected typhoid fever. The Widal test was examined using a microscope to see the agglutination formed, while the number of lymphocytes was calculated using a hematology analyzer. The results of the Widal test with a titer of 1/160 were 63.3% with normal lymphocyte counts and 10% with low lymphocytes. While the titer 1/320 obtained 10% of respondents with normal lymphocyte count and 16.7% with low lymphocyte count. The research design used was analytic observation with the type of cross sectional study. Statistical analysis using Kendall's Tau-b correlation test with SPSS. From the correlation test, the significance value is 0.009, and the correlation coefficient is -0.404**, which means that there is a relationship between the Widal titer and the number of lymphocytes with sufficient closeness.]]>
