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All Journal Biogenesis: Jurnal Ilmiah Biologi
Mustika Ayu Wulansari
Universitas Negeri Malang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Ekstrak Tempe Kedelai Hitam dan Ubi Jalar Ungu Terhadap Toleransi Darah Tikus Model DMT2 Mustika Ayu Wulansari; Sri Rahayu Lestari; Abdul Gofur
Biogenesis: Jurnal Ilmiah Biologi Vol 6 No 1 (2018)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v6i1.4236

Abstract

Diabetes mellitus type 2 (DMT2) is caused by the ineffective use of insulin by the body. DMT2 with hyperglycemia causes circulatory system disorders, such as intracellular ion imbalance that causing changes in cell size and cell membrane fragility. Soybean black tempe and purple sweet potato have a potential therapy for patients with DMT2. This study aims to determine the blood osmotic tolerance of rat model DMT2 treated by the mixture of black soybean tempe extract and purple sweet potato. Osmotic tolerance is indicated by the level of erythrocyte membranes damage, i.e. crenation and hemolysis. The results showed that chemical compounds such as glibenclamide works better to lowers damaging of the cell membrane as compared to treatment of a mixture of natural compounds soybean black tempe and purple sweet potato.
Co-Authors Abdul Gofur Sri Rahayu Lestari