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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) Jurnal Online Mahasiswa (JOM) Bidang Kedokteran
Rizki Giofani
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Public Health

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Analisis Penggunaan Antibiotik pada Pasien Sepsis Neonatus di RSUD Arifin Ahmad Provinsi Riau Nazardi Oyong; Inayah Inayah; Yuni Novita; Rizki Giofani
Jurnal Ilmu Kedokteran Vol 11, No 2 (2017): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (87.187 KB) | DOI: 10.26891/JIK.v11i2.2017.12-17

Abstract

Sepsis that is commonly caused by bacterial infection may cause death in neonates. The appropiate antibioticadministered will increase the life expectancy of neonates with sepsis. Objective of this study was to know the patternof antibiotic use and appropriateness of antibiotic use based on sensitivity test. The study used observational methodwith cross sectional design. The collected data were retrospective. The study population were neonates with sepsis inperinatal ward from Januari – December 2014. The criteria of inclusion were positive blood culture with sensitivity testsand use of antibiotics. The percentage of particular antibiotics used in neonates with sepsis before sensitivity testwere amikacin 64,3%; meropenem 62,9% and piperazine/tazobactam 50% with suitability of 27,1%. However, aftersensitivity test there were meropenem 38,6%, amikacin 30%, vancomycin 14,3% and piperaciline/tazobactam 14,3%with appropriateness of 64,3%. The most number of antibiotic used before and after sensitivity test were amikacin andmeropenem, respectively. There was a suitability enhancement between the use of antibiotics and sensitivity testresults.
EVALUATION USAGE OF ANTIBIOTIC TO SEPSIS NEONATUS PATIENT IN RSUD ARIFIN ACHMAD PROVINCE RIAU Rizki Giofani; Nazardi Oyong; Inayah "
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 3, No 2 (2016): Wisuda Oktober 2016
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

ABSTRACTSepsis neonatus is systemic clinical syndrome usually accompanied withbacteremia that needed prompt and proper antibiotic therapy. This study purposewas evaluating usage of antibiotic to sepsis neonatus patient in RSUD Arifin AchmadProvince Riau. This study method was descriptive retrospective. Data sources weretaken from medical record of sepsis neonatus patient in RSUD Arifin AchmadProvince Riau period 1 January - 31 December 2015. Based on characteristic ofpatient, neonatal sepsis mostly found on female 57,4%, low birth weight 57,8%, lowgestational age 66,2%, and pervaginum labor 52,9%. Blood culture time, found thatmost culture more than 3 days 63,2%. Microorganism of cause mostly foundCoagulase Negative Staphylococci 35,3%. Usage of empirical antibiotics mostlygiven 2 antibiotics 60,3%, type of antibiotic was aminoglycoside 42,1%, withduration more than 72 hours 55,5%. Usage of definitive antibiotics mostly were notgiven to sepsis neonatus patient 44,1%, while mostly they were given single antibiotic30,9%, most used type of antibiotic were aminoglycoside 40% (20 of 60 antibiotics),and duration less than 7 days 50% (30 of 60 antibiotics). Conclusion of this studywere duration of empiric antibiotics mostly given combination of two antibiotics withduration more than 72 hours and empiric antibiotics were suitable withmicroorganism that caused sepsis in RSUD Arifin Achmad 2015.Key word : sepsis neonatus, empiric antibiotic, definitive antibiotic
EVALUATION USAGE OF ANTIBIOTIC TO SEPSIS NEONATUS PATIENT IN RSUD ARIFIN ACHMAD PROVINCE RIAU Rizki Giofani; Nazardi Oyong; Inayah "
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 3, No 2 (2016): Wisuda Oktober 2016
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACTSepsis neonatus is systemic clinical syndrome usually accompanied withbacteremia that needed prompt and proper antibiotic therapy. This study purposewas evaluating usage of antibiotic to sepsis neonatus patient in RSUD Arifin AchmadProvince Riau. This study method was descriptive retrospective. Data sources weretaken from medical record of sepsis neonatus patient in RSUD Arifin AchmadProvince Riau period 1 January - 31 December 2015. Based on characteristic ofpatient, neonatal sepsis mostly found on female 57,4%, low birth weight 57,8%, lowgestational age 66,2%, and pervaginum labor 52,9%. Blood culture time, found thatmost culture more than 3 days 63,2%. Microorganism of cause mostly foundCoagulase Negative Staphylococci 35,3%. Usage of empirical antibiotics mostlygiven 2 antibiotics 60,3%, type of antibiotic was aminoglycoside 42,1%, withduration more than 72 hours 55,5%. Usage of definitive antibiotics mostly were notgiven to sepsis neonatus patient 44,1%, while mostly they were given single antibiotic30,9%, most used type of antibiotic were aminoglycoside 40% (20 of 60 antibiotics),and duration less than 7 days 50% (30 of 60 antibiotics). Conclusion of this studywere duration of empiric antibiotics mostly given combination of two antibiotics withduration more than 72 hours and empiric antibiotics were suitable withmicroorganism that caused sepsis in RSUD Arifin Achmad 2015.Key word : sepsis neonatus, empiric antibiotic, definitive antibiotic
Co-Authors Inayah " Inayah Inayah Nazardi Oyong Yuni Novita