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All Journal Jurnal Sain Veteriner Indonesian Journal of Biotechnology Journal of Tropical Biodiversity and Biotechnology JURNAL KAJIAN VETERINER Jurnal Nasional Teknologi Terapan Jurnal Kedokteran Hewan
Aris Haryanto
Fakultas Kedokteran Hewan Universitas Gadjah Mada
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Electrical & Electronics Engineering Environmental Science Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Veterinary

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Journal : JURNAL KAJIAN VETERINER

 1 
Perubahan Patologis Hepar Akibat Cemaran Aflatoksin B1 Pada Pakan Ayam Pedaging Komersial Di Kota Kupang Devi Y. J. A. Moenek; Aris Haryanto; Charles Rangga Tabu
JURNAL KAJIAN VETERINER Vol 4 No 1 (2016): Jurnal Kajian Veteriner
Publisher : FAKULTAS KEDOKTERAN HEWAN UNIVERSITAS NUSA CENDANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jkv.v4i1.1010

Abstract

Aflatoxin B1 is a secondary metabolite of Aspergillus flavus, Aspergillus parasiticus, and Penicillium puberulum fungus, which is frequently found as contaminants of feed/raw materials of poultry feed. Such compounds have toxic and carcinogenic effects that can cause damage to various tissues/organs, which can further decrease the performance of broiler and cause various degrees of immunosuppressive effects. This study was designed to evaluate the most common pathological lesion in the liver of commercial broiler after consumption of aflatoxin contamination feed in Kupang City of East Nusa Tenggara Province. The research was conducted on 10 broiler farms in Kupang City. Samples of liver were taken for further processing according to the staining method of haematoxylin and eosin (H&E). The results of pathological examination of tissues were analyzed descriptively. Based on the results of this experiment, it can be concluded that pathological examination on the liver showed an early-stage of liver cirrhosis, atrophy of bursa fabricius, thymus and lien due to the necrosis and depletion of lymphocytes.
Co-Authors Charles Rangga Tabu Diana Savitri Diana Savitri Dini Wahyu Yudianingtyas Duhita Andinita Hevi Wihadmadyatami Ida Tjahajati Irhamna Putri Irhamna Putri Medania Purwaningrum Moenek, Devi Y.J.A. Muh. Disna Faizal Nastiti Wijayanti Nastiti Wijayanti Ratu Fresa Khoirotunnisa Hidayat Rini Widayanti Sofia Mubarika Sri Handayani Irianingsih Teuku Zahrial Helmi Teuku Zahrial Helmy Verawati Verawati Warih Pulung Nugrahani Warih Pulung Nugrahani