RISZA HARTAWAN
Indonesia Research Center for Veterinary Science Indonesian Agency for Agricultural Research and Development Jalan R.E. Martadinata No. 30, PO Bx 52 Bogor 16114, West Java, Indonesia

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Journal : WARTAZOA Indonesian Bulletin of Animal and Veterinary Sciences

Development of Recombinant Vaccine Using Herpesvirus of Turkey (Hvt) as Vector for Several Viral Diseases in Poultry Industry Hartawan, Risza
Indonesian Bulletin of Animal and Veterinary Sciences Vol 21, No 1 (2011)
Publisher : Indonesian Animal Sciences Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (464.365 KB) | DOI: 10.14334/wartazoa.v21i1.952

Abstract

Herpesvirus of turkey (HVT) has been utilised as live vaccine against Marek’s disease in poultry industry world-wide for many years. However, the potency of HVT is not limited on the Marek’s disease only. Along with rapid development of recombinant technique, the potency of HVT can be broaden for other diseases. As naturally apathogenic virus, HVT is a suitable candidate as vector vaccine to express important antigens of viral pathogens. Several researches have been dedicated to design HVT recombinant vaccine by  inserting gene of important virus, such as Marek’s disease virus (MDV), immuno bursal disease virus (IBDV), Newcastle disease virus (NDV) and Avian Influenza virus (AIV). Therefore, the future recombinant of HVT has been expected to be better in performance along with the improvement of recombinant technique. Key words: Herpesvirus of turkey, live vector vaccine, viral pathogens