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All Journal Jurnal Kesehatan Andalas Indonesian Journal of Cardiology Majalah Kedokteran Andalas Human Care Journal Jurnal Ilmu Kesehatan Indonesia
Mefri Yanni
Bagian Kardiologi Dan Kedokteran Vaskular Fakultas Kedokteran Universitas Andalas Padang (FK Unand)
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Profil Penderita Stenosis Mitral Reumatik di RSUP Dr. M. Djamil Padang Tahun 2012-2016 Mentari Brillianti Permataranny; Mefri Yanni; Hendra Permana
Jurnal Kesehatan Andalas Vol 8, No 1 (2019): Online Maret 2019
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v8i1.967

Abstract

Penyakit Jantung Reumatik (PJR) masih memiliki prevalensi serta tingkat morbiditas dan mortalitas yang tinggi di negara berkembang, termasuk di Indonesia. Stenosis Mitral Reumatik (SMR) merupakan salah satu penyakit katup jantung yang paling sering terjadi pada PJR, namun data penelitian yang tersedia mengenai SMR di Indonesia masih sedikit. Tujuan penelitian ini adalah untuk mengetahui profil penderita SMR di RSUP Dr. M. Djamil Padang tahun 2012 sampai 2016. Ini adalah studi deskriptif dengan pendekatan retrospektif yang dilaksanakan sejak September 2017 sampai Januari 2018 di RSUP. Dr. M. Djamil Padang di bagian rekam medis. Yang memenuhi kriteria inklusi dijadikan sampel penelitian dengan menggunakan teknik total sampling. Proporsi SMR pada penelitian ini adalah 62% dari seluruh kasus stenosis mitral (SM), mayoritas pasien SMR memiliki stenosis derajat berat (rerata MVA 1±0,5 cm2). Pasien SMR mayoritas adalah perempuan, berusia 31-40 tahun (rerata 39,7±12,8), tidak bekerja, berpendidikan terakhir SMA, memiliki keluhan utama dispnea, dan memiliki NYHA functional class II. Seluruh pasien menerima pengobatan medis dan hanya enam pasien yang menjalani BMV atau operasi. Komplikasi yang paling banyak diderita pasien SMR adalah hipertensi pulmonal dan kelainan katup reumatik lain yang paling sering menyertai SMR adalah regurgitasi mitral. Simpulan studi ini ialah terdapat kesamaan karakteristik pasien SMR pada penelitian ini dengan tren karakteristik dari negara berkembang lainnya.
Gambaran Klinis Penderita Penyakit Ginjal Kronik yang Menjalani Hemodialisis di RSUP Dr. M. Djamil Padang Sitifa Aisara; Syaiful Azmi; Mefri Yanni
Jurnal Kesehatan Andalas Vol 7, No 1 (2018)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v7i1.778

Abstract

Gambaran klinis Penyakit Ginjal Kronik (PGK) terlihat nyata bila ureum darah lebih dari 200 mg/dl. Uremia menyebabkan gangguan fungsi hampir semua sistem organ seperti; gangguan cairan dan elektrolit, metabolikendokrin, neuromuskular, kardiovaskular dan paru, kulit, gastrointestinal, hematologi serta imunologi. Hemodialisis merupakan suatu usaha untuk mengurangi gejala uremia tersebut, sehingga gambaran klinis pasien juga dapat membaik. Tujuan penelitian ini adalah untuk mengetahui gambaran klinis penderita PGK yang menjalani hemodialisis di RSUP Dr. M. Djamil Padang. Jenis penelitian ini adalah deskriptif observasional. Sampel mencakup semua pasien PGK yang menjalani hemodialisis di RSUP Dr. M. Djamil Padang tahun 2015 yang memenuhi kriteria inklusi, sehingga didapatkan sebanyak 104 sampel. Jenis data adalah data sekunder yang diperoleh dari rekam medik. Hasil penelitian menunjukkan kebanyakan pasien adalah kelompok usia 40-60 tahun sebanyak 62,5% dan sebagian besar jenis kelamin pria sebanyak 59 pasien (56,7%). Gambaran klinis paling banyak berupa keadaan gizi sedang 94,2%, diikuti dengan kadar Hb 7-10g/dl 68,3%, konjungtiva anemia 62,5%, edema perifer 53,8%, hipertensi derajat 1 32,7%, lemah, letih, lesu sebanyak 30,8%, dan mual 12,5%. Simpulan penelitian ini adalah gambaran klinis penderita PGK yang menjalani hemodialisis di RSUP Dr. M. Djamil Padang terbanyak yaitu anemia hipertensi derajat satu, keadaan gizisedang, konjungtiva anemia, dan edema perifer.
Profil Klinis Pasien Fibrilasi Atrium di RSUP Dr. M. Djamil Padang Periode 1 Januari – 31 Desember 2017 Alya Binti Azmi; Mefri Yanni; Efrida Efrida
Jurnal Kesehatan Andalas Vol 9, No 1S (2020): Online January 2020
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v9i1S.1148

Abstract

Fibrilasi Atrium (FA) merupakan aritmia tersering di seluruh dunia dengan tingkat insidensi yang terus meningkat. Pasien FA secara umumnya memiliki kelainan struktural pada atrium. Terapi umum adalah antikoagulan untuk pencegahan stroke dan pengendalian laju dan irama jantung. Tujuan: Mengetahui profil klinis pasien FA di RSUP Dr. M. Djamil Padang periode 1 Januari sampai 31 Desember 2017. Metode: Ini adalah penelitian deskriptif. Data sekunder diambil dari rekam medik RSUP Dr. M. Djamil Padang pada November–Desember 2018 secara total sampling. Populasi penelitian adalah semua pasien FA di Instalasi Pusat Jantung Terpadu RSUP Dr. M. Djamil Padang periode 1 Januari sampai 31 Desember 2017. Sampel penelitian adalah semua pasien FA yang memenuhi kriteria inklusi. Hasil: Dari 56 sampel penelitian didapatkan proporsi laki-laki dan perempuan sama banyak (50,0%). Pasien dengan jenis FA valvular dan nonvalvular adalah sebanyak 50,0%. Mayoritas pasien FA usia ≥ 60 tahun (48,2%). Sebanyak 50,0% pasien mempunyai etiologi penyakit katup jantung. Pasien yang mempunyai komorbiditas penyakit ginjal kronik adalah sebanyak 25,0%. Keluhan terbanyak adalah sesak nafas (37,5%). Mayoritas pasien mempunyai skor CHA2DS2-VASc ≥ 2 (83,9%) dan skor HAS-BLED 0–2 (83,9%). Tatalaksana tersering dilakukan adalah terapi kendali laju (82,1%). Terapi antikoagulan yang sering diberikan pada pasien adalah jenis antikoagulan baru (57,1%). Komplikasi terbanyak adalah gagal jantung (82,1%).
Pemeriksaan Diastolic Stress Test Dalam Menilai Gangguan Diastolik Dan Peningkatan Tekanan Pengisian Ventrikel Kiri Mefri Yanni; Nia Kasmiati; Nani Nani
Jurnal Kesehatan Andalas Vol 8, No 2 (2019): Online Juni 2019
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v8i2.1020

Abstract

Peningkatan tekanan pengisian ventrikel kiri merupakan salah satu penyebab sesak napas saat aktifitas. Kondisi klinis ini sering ditemukan pada pasien dengan ganguan miokardium tahap awal seperti pasien penyakit jantung hipertensi maupun diabetes dan bersifat independen dari iskemia. Fraksi ejeksi ventrikel kiri umumnya normal dan meskipun sekelompok pasien ini disebut memiliki gagal jantung diastolik, gambaran fungsi diastolik saat istirahat dapat ditemukan normal. Uji latih secara invasif untuk menilai gambaran hemodinamik pada pasien tersebut merupakan baku emas untuk diagnosis gagal jantung diastolik, namun membutuhkan biaya, risiko dan persiapan yang besar sehingga dapat menghambat penggunaan pemeriksaan ini secara luas pada praktek klinis sehari-hari. Berdasarkan rekomendasi American Society of Echocardiography/European Association of Cardiovascular Imaging, pemeriksaan invasif ini dapat digantikan dengan pemeriksaan non invasif menggunakan uji stres ekokardiografi dengan supine bycycle atau treadmill. Diastolic Stress Test (DST) menggunakan ekokardiografi dapat menilai tekanan pengisian ventrikel kiri saat latihan dan berguna untuk menentukan diagnosis dan memberikan informasi prognostik. Tinjauan pustaka ini akan membahas tentang pemeriksaan Diastolic Stress Test pada praktek klinis sehari-hari.
Uji Diagnostik Squatting Stress Echocardiography dengan Angiografi Koroner dalam Mendiagnosis Penyakit Jantung Koroner Andy Rahman; Mefri Yanni; Masrul Syafri
Jurnal Kardiologi Indonesia Vol. 37, No. 4 Oktober - Desember 2016
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v37i4.583

Abstract

Background: In patients with significant coronary heart disease (CHD), increased preload and afterload during a squat can cause wall motion abnormalities (WMA) which can be detected on echocardiography. This study was conducted to determine the diagnostic value of stress echocardiography squatting as a non-invasive examination of a relatively simple, inexpensive, and safe in the detection of coronary artery stenosis in stable CHD and unstable angina patients.Methods: This study was a cross-sectional design. The subjects were all patients with stable CHD and unstable angina whom were treated in Instalasi Pusat Jantung Rumah Sakit Dr. M. Djamil Padang from May to July 2016. Subjects underwent squatting stress echocardiography procedures followed by coronary angiography. Diagnostic test was used to determine the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of squatting stress echocardiography.Results: The sensitivity, specificity, and accuracy of squatting echocardiography for diagnosis of CAD were 90.3%, 88.9% and 89.7%, respectively.Conclusion: Squatting stress echocardiography can be proposed as a non-invasive examination which is relatively simple, inexpensive and safe to detect coronary artery stenosis on patients with stable CHD and unstable CHD.
Hubungan antara Rasio Panjang Katup Mitral Posterior-Anterior dan Derajat Keparahan Stenosis Mitral Rematik Citra Kiki Krevani; Mefri Yanni; Yerizal Karani; Masrul Syafri
Jurnal Kardiologi Indonesia Vol. 38, No. 1 Januari-Maret 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i1.673

Abstract

Background: Rheumatic mitral stenosis (RMS) is the cause of mitral valve disease commonly found in developing countries. Determining severity of RMS is very important, related with prognosis and management of the disease. Current echocardiography methods have advantages and disadvantages in determining the severity of RMS. Posterior to anterior mitral valve leaflets length ratio (PMVL/ AMVL ratio) was proposed to be one of the semi-quantitative measurement which offered a simple, easy and accurate method in determining the severity of RMS. The aim of this study was to see the association of posterior to anterior mitral valve leaflets length ratio with severity of rheumatic mitral stenosis.Methods: This was a cross-sectional descriptive analytic study. The subjects were all patients with rheumatic mitral stenosis who underwent echocardiography examination to measure the PMVL/AMVL ratio as well as determining the severity based on mitral valve area (MVA) planimetry. One-way ANOVA analytic test was used to assess the association of ratio PMVL/AMVL and severity of the RMS.Results: Of 71 patients included in this study, there were 19 mild RMS, 19 moderate RMS and 33 severe RMS patients. Majority of the subjects were female with age range from 38 to 43 years and have atrial fibrillation. From echocardiography examination, the mean EF +/- 55% with increased LAVI and SPAP according to the severity of the RMS (LAVI; 44±1.3 vs. 55±1.5 vs. 74±1.7 ml/m2 SPAP; 29±1.2 vs. 46±9.0 vs. 68±1.4 mmHg). There was a significant difference in the length of PMVL in mild, moderate and severe RMS (28±5.6 vs. 22±4.0 vs. 17±5.2 mm; p<0.001), but no significant difference in the length of AMVL (33±5.5 vs 33±5.4 vs 32±5.1mm; p=0.93) respectively. The PMVL/AMVL ratio had statistically significant association with severity of RMS (p<0.001).Conclusion: The PMVL/AMVL ratio is significantly associated with severity of RMS.
Diagnostic Value of Left Ventricular Early Inflow-Outflow Index in Determining Severity of Mitral Regurgitation Vera Yulia; Mefri Yanni; Didik Hariyanto
Jurnal Kardiologi Indonesia Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i2.729

Abstract

Background: Determining severity of mitral regurgitation (MR) is very important, asit is related with prognosis and management of the disease. Currently, there is no goldstandard exists for quantification of MR severity using echocardiography. AmericanSociety of Echocardiography (ASE) guidelines recommend several parameters basedon integrative criteria using color and spectral Doppler and anatomic measurement.Left Ventricular Early Inflow Outflow Index (LVEIO Index) was proposed as one parameterto assess the severity of MR by omitting geometric error from regurgitantvolume method. Thus, LVEIO index offers a simple, easy and accurate measurementin determining severity of MR.Methods: This study was a diagnostic test research with cross-sectional design. Thesubjects were all patients with organic mitral regurgitation who underwent echocardiographyexamination to measure severity of MR using the LVEIO index as well asother parameters measurements based on parameters of ASE guidelines. Diagnostictest was used to determine the sensitivity, specificity, positive predictive value, negativepredictive value and accuracy of LVEIO index.Results: Of 49 patients in this study, 23 of them have severe MR and 26 are non-severeMR patients. The proportion of gender between two groups almost similar with an agerange from 56 to 61 years and the most common etiology finding was degenerative MR.Echocardiography examination showed the ejection fraction in severe MR was 63±4.2%and 64±3.9% in non-severe MR. The value of LAVI, MPAP, E-wave, VC, EROA andLVEIO index increased parallel with severity of MR (LAVI; 67±18.2 vs. 40±14.2 ml/m2,MPAP; 28±12.8 vs. 20±12.6 mmHg, E-wave 1.5±0.3 vs. 1±0.2 m/s, VC 0.8±0.3 vs.0.5±0.1 cm, EROA 0.4±0.1 vs 0,2±0,1cm2, LVEIO 9±2,4 vs. 5±1,8). The sensitivity,specificity, and accuracy of LVEIO index for diagnosis of severe MR were 86%, 84%,and 89%, respectively.Conclusion: LVEIO can be proposed as a relatively simple, easy and accurate methodin determining severity of MR.
Nilai Diagnostik Tebal Lemak Epikardial dalam Mendeteksi Lesi Koroner pada Pasien Angina Pektoris Stabil Ulzim Fajar; Mefri Yanni; Muhammad Syukri
Jurnal Kardiologi Indonesia Vol 41 No 4 (2020): Indonesian Journal of Cardiology: October - December 2020
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1048

Abstract

Background: Abdominal visceral adiposity is a risk factor of cardiovascular diseases. It correlates with increasing level of pro-inflammatory adipokines and cytokines which can induce endothelial dysfunction. Epicardial adipose tissue is considered as true visceral adiposity of the heart. Epicardial adipose tissue have pivotal role than other visceral adiposity because of adjacency to the heart and coronary vessels. This study was aimed to measure the cut off point of epicardial fat thickness as a diagnostic marker for the presence of coronary lesion. Methods: This was an observational analytic study with crossectional comparative design. Data was retrieved prospectively at the Heart Center Dr. M. Djamil Padang from August 2019 to February 2020 in stable angina pectoris patients who underwent coronary angiography. The Epicardial Fat Thickness (EFT) was measured at end-diastole from the Parasternal long axis (PLAX) views of three cardiac cycles on the free wall of the right ventricle on echocardiography examination. Bivariate analysis was used to assess epicardial fat thickness and presence of the coronary lesions using Independent Sample T test. A diagnostic test was performed based on receiver operating curve (ROC) analysis. Results: Patients were diagnosed as CAD group group (n =150; 58,11 ± 8,24 years) and non-CAD group (n = 50; 53,16 ± 9,78 years) based on coronary angiogram result. Epicardial fat thickness was higher in subjects with coronary lesions (3,62 ± 1,03 mm) compared with subjects without coronary lesions (1,55 ± 1,10 mm) with p <0.001. Epicardial fat thickness ≥ 2.835 mm predict the presence of coronary lesion by 82% sensitivity, 86% specificity and 88.9% accuracy based on the AUC value. Conclusions: Abnormal epicardial fat thickness ≥ 2.835 mm can be a good diagnostic marker to detect the presence of coronary lesion.
PERBEDAAN EKOKARDIOGRAFI PADA JANTUNG ATLET, HIPERTENSI, DAN KARDIOMIOPATI HIPERTROFI Finesa Hasye; Mefri Yanni
Majalah Kedokteran Andalas Vol 43, No 2 (2020): Online Mei 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v43.i2.p134-147.2020

Abstract

Hipertrofi ventrikel kiri didefinisikan sebagai peningkatan massa ventrikel kiri. Peningkatan massa miokard karena latihan intensif yang teratur "jantung atlet" merupakan hal yang biasa. Meskipun terdapat korelasi langsung dengan beban latihan, hipertrofi miokard tidak hanya terjadi pada atlet. Jantung atlet dianggap sebagai fenomena fisiologis tanpa menimbulkan bahaya. Namun, bentuk lain hipertrofi miokard seperti kardiomiopati hipertrofi atau penyakit jantung hipertensi berhubungan dengan peningkatan risiko kejadian kardiovaskular. Echocardiography memainkan peran penting dalam diagnosis, strategi manajemen, dan prognostik penyakit kompleks ini. Perbedaan antara hipertrofi fisiologis dan patologis mungkin memiliki dampak besar, karena kardiomiopati hipertrofi yang tidak terdiagnosis merupakan salah satu penyebab paling umum kematian jantung mendadak pada atlet, sedangkan identifikasi penyakit kardiovaskular pada atlet dapat menjadi dasar untuk diskualifikasi dari kompetisi. Tinjauan pustaka ini akan membahas perbedaan hipertrofi fisiologis dan patologis.Kata kunci: Hipertrofi ventrikel kiri; jantung atlet; kardiomiopati hipertrofi; penyakit jantung hipertensi.
PERAN LEMAK EPIKARDIAL PADA PENYAKIT JANTUNG KORONER STABIL Ulzim Fajar; Mefri Yanni
HUMAN CARE JOURNAL Vol 5, No 2 (2020): Human Care Journal Special Edition
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i2.780

Abstract

Visceral fat tissue widely known have endocrine function by secreting Cytokines that provide it function in metabolism of visceral organ such as heart. It function have pivotal role under physiology and patology condition by secreting antiinflamatory cytokines in physiology condition, otherwise  proinflammatory cytokines in patology condition. Epicardial fat tissue as regard this function, have more important role to the heart, because it have two advantage than other visceral depots. First, this tissue have same microcirculation provided by small branch of coronary arteries, and second it were not boundary by any structure. Recent studies found that there were correlation between increased epicardial fat depot and coronary artery disease. It seems correlate with this unique structure and function. This literature review focuse on how is the role of epicardial fat tissue in atheroschlerotic process especially in coronary artery.
Co-Authors Adhi Kurniawan Alya Binti Azmi Andy Rahman Citra Kiki Krevani Dede Jumatri Tito Didik Hariyanto Efrida Efrida Finesa Hasye Gusti Revilla Hendra Permana Herman, Deddy Ihsan Otriami Ilmiawati, Ilmiawati Masrul Syafri Masrul Syafri Mentari Brillianti Permataranny Mohamad Reza Nandia Rizkita Nani Nani Nia Kasmiati Salsa Oktarin Letmi Saptino Miro Sitifa Aisara Syaiful Azmi Ulzim Fajar Ulzim Fajar Vera Yulia Yasmin Nabila Ramadhani Yayi Suryo Prabandari Yerizal Karani