Mefri Yanni
Bagian Kardiologi Dan Kedokteran Vaskular Fakultas Kedokteran Universitas Andalas Padang (FK Unand)

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Journal : Human Care Journal

PERAN LEMAK EPIKARDIAL PADA PENYAKIT JANTUNG KORONER STABIL Ulzim Fajar; Mefri Yanni
HUMAN CARE JOURNAL Vol 5, No 2 (2020): Human Care Journal Special Edition
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i2.780

Abstract

Visceral fat tissue widely known have endocrine function by secreting Cytokines that provide it function in metabolism of visceral organ such as heart. It function have pivotal role under physiology and patology condition by secreting antiinflamatory cytokines in physiology condition, otherwise  proinflammatory cytokines in patology condition. Epicardial fat tissue as regard this function, have more important role to the heart, because it have two advantage than other visceral depots. First, this tissue have same microcirculation provided by small branch of coronary arteries, and second it were not boundary by any structure. Recent studies found that there were correlation between increased epicardial fat depot and coronary artery disease. It seems correlate with this unique structure and function. This literature review focuse on how is the role of epicardial fat tissue in atheroschlerotic process especially in coronary artery.
PERUBAHAN MORFOLOGI KATUP MITRAL PADA DEMAM REMATIK AKUT DAN PENYAKIT JANTUNG REMATIK Dede Jumatri Tito; Mefri Yanni
HUMAN CARE JOURNAL Vol 5, No 2 (2020): Human Care Journal Special Edition
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i2.779

Abstract

Rheumatic fever and rheumatic heart disease remains a significant cause of cardiovascular disease in the world, especially in industrial countries and developing countries. Rheumatic heart disease is the most serious complication of rheumatic fever which is characterized by the occurrence of heart valve defects are most of the mitral valve, aortic and tricuspid followed. Valvulitis or inflammatory process in the tissue of the mitral valve causing edema of the valve leaflets and chordae tendineae, causing disruption valve closure is causing mitral regurgitation. Eventually fibrosis and calcification of the valve that causes stiffness and the valve leaflets into mitral valve stenosis. The earliest possible introduction of cardiac involvement in rheumatic heart disease is an important part in the prevention of further heart damage.
PEMERIKSAAN FUNGSI ENDOTEL PADA PENYAKIT KARDIOVASKULAR Adhi Kurniawan; Mefri Yanni
HUMAN CARE JOURNAL Vol 5, No 3 (2020): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i3.817

Abstract

Cardiovascular risk factors have been known to play a role in vascular endothelial damage. Endothelial damage can cause a condition called endothelial dysfunction. Endothelial dysfunction  is the initial process of various cardiovascular problems such as coronary heart disease, stroke, peripheral artery disease, and  others. Early stage endothelial damage can actually be detected, but often patients present at the stage of cardiovascular problems. Various examinations of endothelial function start from invasive, non invasive, until biomarkers marking the occurrence of dysfunction can be done. So that we can prevent or reduce the occurrence of further damage