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All Journal BioWallacea Journal of Biological Research Indonesian Journal of Biotechnology INDONESIAN JOURNAL OF PHARMACY Jurnal Medika: Media Ilmiah Analis Kesehatan Life Science JURNAL BIOLOGI PAPUA
Barinta Widaryanti
Akademi Analis Kesehatan Manggala Yogyakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Veterinary

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Journal : BioWallacea Journal of Biological Research

 1 
PENGARUH REBUSAN GAMBAS (Luffa cilindrica) TERHADAP KADAR GLUKOSA DARAH DAN PROFIL LIPID PADA TIKUS WISTAR DIABETES Barinta Widaryanti; Arshita Eka Kurniawati; Nuriansyah Putri
BioWallacea : Jurnal Penelitian Biologi (Journal of Biological Research) Vol 3, No 1 (2016): BIodiversitas
Publisher : University of Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33772/biowallacea.v3i1.1481

Abstract

ABSTRACT Diabetets mellitus is a common desease which is caused by insulin secretion and action disorder. Prevelence of the desease was predicted to be increase 2,5 times in 2030, therefore, special treatment were needed to improve the quality of life diabetic patient. Recently, many natural drug has been developed for diabetic therapy. The objective of this research was to investigate the effect of boiled sponge gourd in reducing blood glucose dan lipid profile on male diabetic rats alloxan induced. Eighteen diabetic male wistar rats were divided into three groups, first grup were normal rats, second gorup were diabetic rats,and third gorup were diabetic rats that were treated with boiled sponge gourd for fourtheen days. The research showed that boiled sponge gourd was able to reduce blood glucose, total cholesterol and triglyceride. Keywords : Diabetes mellitus, gambas, anti diabetic drug, alloxan
Efek Rebusan Sereh (Cymbopogon citratus) Terhadap Kadar Glukosa dan Profil Lipid Tikus Wistar Diabetes Barinta Widaryanti; F Linda Tripramatasari
BioWallacea : Jurnal Penelitian Biologi (Journal of Biological Research) Vol 8, No 1 (2021): BioWallacea : Jurnal Penelitian Biologi (Journal of Biological Research)
Publisher : University of Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (881.558 KB) | DOI: 10.33772/biowallacea.v8i1.16071

Abstract

Diabetes mellitus adalah kelainan metabolisme yang ditandai dengan hiperglikemia. Kenaikan prevalensi diabetes menjadi ancaman yang serius di dunia. Oleh karena itu  perlu pengaturan pengobatan yang sesuai untuk meningkatkan kualitas hidup. Penggunaan natural produk untuk terapi diabetes telah banyak dikembangkan. Tujuan penelitian ini adalah untuk mengetahui efek rebusan  sereh terhadap kadar glukosa darah dan profil lipid pada tikus diabetes yang diinduksi aloksan 150 mg/kg bb single dose. Duapuluh empat tikus wistar jantan dengan usia 8 minggu dibagi menjadi empat kelompok: kelompok tikus normal, tikus diabetes, tikus diabetes dengan perlakuan glibenklamid dan tikus diabetes dengan perlakuan sereh 0.9 ml/200 g berat badan. Rebusan sereh diberikan secara oral selama 14  hari pada tikus diabetes. Kadar glukosa darah, HDL, LDL, trigliserida dan total kolesterol  diukur menggunakan metode enzimatik kolorimetrik. Hasil penelitian menunjukkan bahwa rebusan sereh mampu menurunkan kadar glukosa darah, LDL, kolesterol total, meningkatkan kadar HDL, namun tidak berpengaruh terhadap kadar trigliserida. Gambaran histologi pankreas menunjukkan perbaikan sel. 
Co-Authors Anggun Permata Sari Simbolon Arshita Eka Kurniawati Edy Meiyanto F Linda Tripramatasari Habib Khayrul ikhwan Nur Hakim Masashi Kawaichi Masashi Kawaichi Muhammad Da'i Muhammad Da’i Nunung Sulistyani Nur Khikmah Nuriansyah Putri Subrata Tri Widada Tiya Kumalasari