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All Journal WMJ (Warmadewa Medical Journal) Biology, Medicine, & Natural Product Chemistry Warmadewa Minesterium Medical Journal
Made Dharmesti Wijaya
Warmadewa University
Biochemistry, Genetics & Molecular Biology Education Health Professions Library & Information Science Medicine & Pharmacology Public Health

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Journal : WMJ (Warmadewa Medical Journal)

 1 
Evaluating Helminth to Treat Type 2 Diabetes – A Review Made Dharmesti Wijaya; Anak Agung Gede Indraningrat
WMJ (Warmadewa Medical Journal) Vol 4 No 1 (2019): May 2019
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.4.1.1042.21-29

Abstract

Type 2 diabetes (T2D) is characterized by lacking production of insulin and impaired insulin sensitivity. Despite the availability of antidiabetic drugs on the market, exploration of new therapeutic drugs for treating T2D from nature remains necessary. This review provides insights on the potential of helminths and helminth derived products to modulate immune response for treating T2D. We discussed several helminths that are under investigation in animal models for treating T2D namely Schistosoma mansoni, Nippostrongylus brasiliens, Litomosoides sigmodontis, and Strongyloides stercoralis. Finally, application of Schistosoma mansoni soluble egg antigens (SEA) in T2D treatment is also examined.
Co-Authors Anak Agung Gede Indraningrat Anak Agung Gede Indraningrat I Gede Yoga Ayuning Kirtanayasa Ida Ayu Agung Idawati Wahyu Antari Wijaya