Setiawan Setiawan
Bagian Bedah Mulut, Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

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Journal : Interdental Jurnal Kedokteran Gigi (IJKG)

AKTIVITAS ANTIBAKTERI EKSTRAK BUAH MAHKOTA DEWA (Phaleria macrocarpa) TERHADAP Staphylococcus aureus Mochammad Taha Ma’ruf; Setiawan Setiawan; Bayu Prayoga Deta Putra
Interdental: Jurnal Kedokteran Gigi Vol. 13 No. 2 (2017): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v13i2.360

Abstract

Tooth extraction though always not cause problems, but can cause some complications, one of which is endocarditis infection. The infection is caused by Staphylococcus aureus that causes abnormalities of the heart valves. The use of herbal ingredients to be an alternative to antibacterial bacteria as a result of increased resistance to antibiotics. Mahkota Dewa fruit (Phaleria macrocarpa) was selected as an antibacterial because it is active substances contains such as alkaloids, saponins, flavonoids, and polyphenols. The purpose of this study was to determine the effective concentration of the extract Mahkota Dewa fruit as an antibacterial against Staphylococcus aureus that can be made of a product in the form of a gel that can be applied to a tooth extraction wound to prevent endocarditis infection. The study is in vitro an experimental laboratory approaches Post test Only Control Group Design. Samples are distinguished by the concentration differences of the Mahkota Dewa fruit extract are 60%, 70%, 80%, 90% and 100%. The results showed that the Mahkota Dewa fruit extract concentration of 70% effective as an antibacterial against Staphylococcus aureus. The effectiveness of the extract Phaleria influenced by the ability of the active substance content of flavonoids lysis of bacterial cells.
EFEKTIFITAS MINYAK CENGKEH DAN PULPERYL® TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS (secara in vitro) Hendri Poernomo; Setiawan Setiawan; Senopati Senopati
Interdental: Jurnal Kedokteran Gigi Vol. 14 No. 1 (2018): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v14i1.369

Abstract

One of the complications that can occur after tooth extraction is an infection at the extraction site. Staphylococcus aureus is of the bacterias that plays a significant role in causing infection. Eugenol is an active substance of clove oil and pulperyl, where eugenol has antibacterial properties. The aim of the research is to compare the effectivity between clove oil and pulperyl in inhibiting the accumulation of Staphylococcus aureus. The research used in vitro laboratory experimental method by comparing the inhibition rate of clove oil 5% and pulperyl 5% along with a negative control of ethanol against Staphylococcus aureus in form of clear zone measured with a caliper. The medium of culture used was Mueller Hinton Agar (MHA). The result shows that the Pulperyl 5% has an average inhibition zone of 12 mm which is more effective compared to clove oil 5% which has an average inhibition zone 10 mm in inhibiting Staphylococcus aureus. The test result showed statistically significant results (ANOVA test = 0.001 with p<0.05). Pulperyl and clove oil contain eugenol that may damaged protein membrane and inhibit bacterial growth.The conclusion is that Pulperyl 5% and clove oil 5% can inhibit accumulation of Staphylococcus aureus, in which Pulperyl® 5% has higher inhibition rate compared to clove oil 5%.
EFEKTIVITAS MINYAK CENGKEH DAN PULPERYL® DALAM MENGHAMBAT AKUMULASI BAKTERI Streptococcus mutans SECARA IN VITRO Hendri Poernomo; Mochammad Taha Ma'ruf; Setiawan Setiawan; PA Nindya Winda Wati
Interdental: Jurnal Kedokteran Gigi Vol. 14 No. 2 (2018): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v14i2.372

Abstract

One of the complications that can occur after tooth extraction is dry socket. Bacterial infection is one among the various causes of dry socket where Streptococcus mutans become one of the bacteria that have a role as a cause. Eugenol is the main active substancethat owned by clove oil with eugenol as antibacterial properties. The research pyupose was to determine the effectiveness of clove oil in inhibiting the accumulation of Streptococcus mutans bacteria in the dry socket. The research method used to see the inhibition of clove oil 5% also the negative control of ethanol to Streptococcus mutans bacteria in the form of clear zone using a vernier caliper. The research result shows that the clove oil 5% effective in inhibiting Streptococcus mutans, with the average inhibition zone of clove oil 5% was 15 mm. Statistical test result showed significant results (ANOVA test = 0.001 with ρ <0.05). The conclusion that can be obtained from this study was clove oil 5%may inhibit the accumulation of Streptococcus mutans bacteria in the dry socket.