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AKTIVITAS ANTIBAKTERI EKSTRAK DAUN RAMBAI (Sonneratia Caseolaris) KONSENTRASI 70%, 80% DAN 90% TERHADAP Streptococcus Mutans IN VITRO Helda Helda; Didit Aspriyanto; R. Harry Dharmawan S
Dentin Vol 4, No 3 (2020)
Publisher : Universitas Lambung Mangkurat

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Abstract

ABSTRACTBackground:. One of the factors causing dental caries is a microorganism, namely Streptococcus mutans. Rambai leaf extract (Sonneratia caseolaris) contain triterpenoids, flavonoids, tannins, steroids and phenols which have antibacterial activity against the growth of Streptococcus mutans which has the potential to prevent dental caries. Purpose: This study aims to prove the presence of 70%, 80% and 90% antibacterial activity of rambai leaf extract (Sonneratia caseolaris) in inhibiting the growth of Streptococcus mutans in vitro. Methods: This study was a laboratory experimental study, with a post test only design, using a completely randomized design consisting of 5 treatment groups, namely: rambai leaf extract 70%, 80% and 90% (Sonneratia caseolaris), positive control. (Povidone iodine 1%) and negative control (distilled water) were repeated 5 times. Antibacterial activity was assessed from the clear inhibition zone formed on Muller Hinton media by diffusion method. Results: The Kruskal-wallis test showed that the clear inhibition zone formed had a significant difference. The average clear zone of rambai leaf extract (Sonneratia caseolaris) was 70% at 11.6 mm, 80% for 12.9 mm and 90% for 14.2 mm. Conclusion: Rambai leaf extract (Sonneratia caseolaris 70%, 80% and 90% have antibacterial activity in inhibiting the growth of Streptococcus mutans in vitro. Keywords: Antibacterial Activities, Rambai Leaf Extract, Streptococcus mutans. ABSTRAK Latar Belakang: Faktor penyebab terjadinya karies gigi salah satunya adalah mikroorganisme yaitu Streptococcus mutans. Ekstrak daun rambai (Sonneratia caseolaris) mengandung triterpenoid, flavonoid, tanin, streoid dan fenol yang  memiliki aktivitas antibakteri terhadap pertumbuhan Streptococcus mutans yang berpotensi sebagai pencegah karies gigi. Tujuan: Tujuan penelitian ini adalah untuk membuktikan adanya aktivitas antibakteri ekstrak daun rambai (Sonneratia caseolaris) 70%, 80% dan 90% dalam menghambat pertumbuhan Streptococcus mutans in vitro. Metode: Penelitian ini merupakan penelitian eksperimental laboratorik murni (true experimental), dengan post-test only design, menggunakan rancangan acak lengkap terdiri dari 5 kelompok perlakuan, antara lain: ekstrak daun rambai (Sonneratia caseolaris) 70%, 80% dan 90%, kontrol positif (Povidone iodine 1%) dan kontrol negatif (akuades) dilakukan pengulangan sebanyak 5 kali. Aktivitas antibakteri dinilai dari zona hambat bening yang terbentuk pada media Muller Hinton dengan metode difusi. Hasil: Uji Kruskal-wallis menunjukkan bahwa zona hambat bening yang terbentuk memiliki perbedaan yang bermakna. Rata-rata zona bening ekstrak daun rambai (Sonneratia caseolaris) yaitu 70% sebesar 11,6 mm, 80% sebesar 12,9 mm dan 90% sebesar 14,2 mm. Kesimpulan: Ekstrak daun rambai (Sonneratia caseolaris) 70%, 80% dan 90% memiliki aktivitas antibakteri dalam menghambat pertumbuhan Streptococcus mutans in vitro. Kata kunci: Aktivitas Antibakteri, Ekstrak Daun Rambai, Streptococcus mutans.
Association of Obesity and Negative Acid-Fast Bacilli Finding Among Pulmonary Tuberculosis Patients with Type 2 Diabetes Mellitus Nadya Magfira; Md Ikhsan Mokoagow; Ida Ayu Kshanti; Helda Helda
Jurnal Epidemiologi Kesehatan Indonesia Vol 3, No 2 (2019)
Publisher : Department of Epidemiology, FoPH, UI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (464.758 KB) | DOI: 10.7454/epidkes.v3i2.3470

Abstract

Obesity is known as protective factors of pulmonary tuberculosis (PTB) innon-diabetes mellitus population. However, it’s effect on PTB in type 2diabetes mellitus (T2DM) patient is unclear. The study aims to determinethe association between obesity and PTB in patient with T2DM. A crosssectional study was held in in-patient, The Department of Internal Medicine, Fatmawati General Hospital from January 2015 to December 2017.This study includes patient with T2DM who had been diagnosed with PTBand age > 18 years old. In this study negative Acid-fast-bacilli (AFB)founding defined as patient’s sputum is negative by smear microscopy,while obesity define as body mass index > 24.9 kg/m2. From 363 PTBpatient with T2DM, 22.59% were obese. Results showed that prevalenceof negative AFB founding in PTB patients with T2DM was 81.82% and itwas solely associated with obesity (p:0.002, OR=6.36, 95%CI 1.9-21). Obesepatients were likely to have negative AFB founding. It suggested thatdiagnosing PTB in patient with T2DM and obese can’t be solely based onbacteriological confirmation
THE EFFECTS OF SECTION CAESAREA TO EARLY BREASTFEEDING INITIATION: A SYSTEMATIC REVIEW Nur Annisa Fauziyah; Helda Helda
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Abstract

Background: The early breastfeeding initiation is one of the crusial process for successful in exclusive breastfeeding, unfortunately based on UNICEF, globally only 45% of newborns were put to the breast within the first hours of life. The other condition, nowdays caesarean sections have become increasingly common in both developed and developing countries, research showed that mothers who delivered their baby section caesarea have a higher percentage failure of early breastfeeding initiation than mother with vaginal delivery, from that condition his research aims to analyze effects section caesarea to early breastfeeding initiation. Methods: This study used systematic review based on the Prisma (Preferred Reporting Items For Systematic Reviews & Meta-Analyses) Protocol to identify all the published literature using relevant keywords. The initial screening was conducted by human population, the year of publication (5 years) and free full text, then reading the titles, abstracts than assessed for eligibility founded 6 articles, those studies included in this review after selected using inclusion and exclusion criteria. Inclusion are journal from rearch reported in english, has no accompanying disease or health problem as cardiac disease, cancer, herpes, HIV/AIDS, obesity ect. The baby is normal, baby can drink orally. Exclusion: the articles published less than 2013, after sectio caesarea mother and infant require special therapy. Results: The studies showed there were effects of section caesarea to early breastfeeding initiation, the mothers who birth their babies with caesarea most of them failure to initiate early breastfeeding. Conclusions: The way to Improve the rates of early breastfeeding initiation with giving antenatal breastfeeding education to all mothers especially who known to be having a cesarean section and health care professionals must support. All of the hospitals must apply baby friendly hospital initiative to support success of early breastfeeding initiation 
Aplikasi Probio_FMPlus melalui Air Minum pada Ayam Broiler di Politani Kupang Ella Hendalia; Fahmida Manin; Revis Asra; Helda Helda
Jurnal Ilmiah Ilmu-Ilmu Peternakan Vol. 20 No. 1 (2017): Mei 2017
Publisher : Fakultas Peternakan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.225 KB) | DOI: 10.22437/jiiip.v20i1.4362

Abstract

The aims of this study was to reveal the effectiveness of the use of Probio_FMplus broiler. Two hundret of day old chick (DOC) were used in this experiment. DOCs were randomly treated into five treatments with five replications consiting of eight DOCs. Treatments were the use of Probio_FMplus within drinking water of 0, 10, 15 and 20 ml/liter for treatment P0, P1, P2, P3and P4 respectively. The design of experiment was Completely Randomized Design with five treatments and five replications. Parametters measured were ration comsumption, weight gain, slaughter weight and feed conversion. The results of this experiment showed that the level of Probio_FMplus in drinking water did not significantly influence (P>0,05) on ration consumption, weight gain, slaughter weight and feed conversion. It could be concluded that the use of 10 ml/liter of Probio_FMplus in dringking waterwas the most effective in broiler. Kata kunci: probiotik, prebiotik, simbiotik, putak
STUDI EKOLOGI : DETERMINAN KEJADIAN GIZI BURUK DI INDONESIA TAHUN 2021 Desyana Endarti Hendraswari; Helda Helda
J-KESMAS: Jurnal Kesehatan Masyarakat Vol 9, No 1 (2023): J-KESMAS Volume 9 Nomor 1, Mei 2023
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Al Asyariah Mandar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35329/jkesmas.v9i1.3899

Abstract

Gizi buruk tidak hanya dapat meningkatkan angka morbiditas dan angka mortalitas, tetapi juga menurunkan produktifitas serta menghambat pertumbuhan sel-sel otak. Prevalensi Gizi Buruk di Indonesia pada balita usia 0-23 bulan (baduta) 4,5%, dan balita usia 0-59 bulan 3,5%. Penelitian bertujuan melihat korelasi antara kejadian gizi buruk dengan penduduk miskin, cakupan imunisasi dasar lengkap, cakupan vitamin A, desa melaksanakan Sanitasi Total Berbasis Masyarakat (STBM), rata-rata konsumsi kalori dan protein masyarakat. Penelitian deskriptif berbasis studi ekologi bersumber dari Profil Kesehatan Indonesia 2021 dan data BPS RI 2021. Hasil penelitian menunjukkan penduduk miskin menunjukkan hubungan cukup (r=0,347) dan korelasi positif, variable cakupan imunisasi lengkap (r=0,467), desa melaksanakan STBM (r=0,436), rata-rata konsumsi kalori (r=0,384) dan protein (r=0,347) menunjukkan hubungan cukup dan korelasi negatif, vitamin A menunjukkan hubungan kuat (r=0,529) dan korelasi negatif terhadap peningkatan persentase gizi buruk. Dapat disimpulkan Terdapat korelasi antara kejadian gizi buruk dengan penduduk miskin, cakupan imunisasi dasar lengkap, cakupan pemberian vitamin A, desa melaksanakan STBM, rata-rata konsumsi kalori dan rata-rata konsumsi protein masyarakat di Indonesia Tahun 2021.