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All Journal Buletin Veteriner Udayana
Ni Putu Trisna Asih
Praktisi Dokter Hewan Gianyar di Blahbatuh, Batuan Kaler, Sukawati Gianyar, Bali, Indonesia 80582
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Kesembuhan Fraktur Tulang Femur Kelinci Pasca Implantasi Bahan Cangkok Demineralisasi Serbuk Tulang Sapi Bali Ni Putu Trisna Asih; I Wayan Wirata; Luh Made Sudimartini; Ida Bagus Oka Winaya; I Made Kardena; I Wayan Gorda
Buletin Veteriner Udayana Vol. 11 No. 2 Agustus 2019
Publisher : The Faculty of Veterinary Medicine, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (663.053 KB) | DOI: 10.24843/bulvet.2019.v11.i02.p13

Abstract

The purpose of this study to determine the microscopic changes in rabbit femur fracture healing post-implantation of the graft material demineralized powder bone of bali cattle. Twelve local male rabbits were divided into two groups randomly. Group A consisted of three rabbits used as a control, in which the diaphysis rabbit femur bones were drilled with a diameter of 5mm and depth of drill to reach the medulla, without giving graft material. Group B nine rabbits that were drilled the same as group A and given a powder bone graft. Monitoring progress of bone healing was done in a row against one rabbits in group A and group B three rabbits at week 2nd, 4th, and 6th post-surgery with biopsy for sampling bone subsequently prepared to see microscopic changes the bone with using hematoxylin-eosin (HE) staining. The results showed that the group B bone healing observ by reducing inflammation, proliferation of fibrolast, osteoblasts, osteoclasts, osteocytes, woven bone, trabecular bone, and neovascularization. In conclusion, the origin of the bone graft material bali cattle was able to induce the healing process of bone fractures in rabbits.
Co-Authors I Made Kardena I Wayan Gorda I Wayan Wirata Ida Bagus Oka Winaya Luh Made Sudimartini