Leni Rokhma Dewi
Bagian Penyakit Mulut FKG Universitas Jember

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Daya Hambat Ekstrak Daun Kakao (Theobroma Cacao L.) terhadap Pertumbuhan Candida Albicans Nadya Indah Permataningrum; Leni Rokhma Dewi; Ayu Mashartini Prihanti
Pustaka Kesehatan Vol 7 No 3 (2019): Volume 7 No.3, 2019
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v7i3.10824

Abstract

Candidiasis is an infection caused by overgrowth of Candida species in the oral cavity dominated by C. albicans. One way to inhibit the growth of the fungi is by utilizing medical plants that contain antifungal compounds. Cocoa leaves is a plants that has antifungal compounds such as caffeine, flavonoids and alkaloids. The aim of study was analyzing the effect of cocoa leaf extract on the growth of C. albicans and determining the optimal concentration of cocoa leaf extract in inhibiting the growth of C. albicans. The study used macerated cocoa leaf extract. The inhibitive testing method conducted by disc diffusion method. The concentrations of cocoa leaf extract were 25%, 50%, 75%, 100%, and nystatin was used as positive control and aquadest was negative control. All were possed on the disc and further incubated for 24 hours. The inhibition effect was measured by a caliper. Cocoa leaf extract can inhibit the growth of C. albicans, and the largest co-concentration in inhibiting C. albicans was 100%.
A comparison of the severity of oral candidiasis between gestational and type 1 diabetes mellitus Ayu Ragil Destrian Pangestu; Siti Nosya Rachmawati; Leni Rokhma Dewi; Mei Syafriadi
Dental Journal (Majalah Kedokteran Gigi) Vol. 52 No. 3 (2019): September 2019
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v52.i3.p110-116

Abstract

Background: Diabetes mellitus is a metabolic disorder caused by insufficient insulin production due to pancreatic β cell destruction, whereas in gestational diabetics an increase of hormone estrogen induces insulin resistance. Oral candidiasis constitutes an opportunistic fungal infection due to a compromised immune system that is a medical condition reported by diabetics, including those suffering from gestational diabetes. Purpose: To determine the severity of oral candidiasis in female Wistar rats with type 1 and gestational diabetes mellitus. Methods: This research constituted a laboratory experiment incorporating a post test-only group control design whose subjects were female Wistar rats divided along the following lines: group 1 consisted of diabetic non-pregnant rats, group 2 contained diabetic pregnant rats induced by streptozotocin and the control group members constituted normal female rats. Diabetes induction was performed by means of 40 mg/kgBW streptozotocin administrated intraperitoneally. Diabetes mellitus was confirmed when the blood glucose level ≥ 120 mg/dL. All groups were exposed to 0.2 ml Candida albicans suspension (5x108 CFU/ml) in the oral buccal vestibule between the distal incisors and mesial maxillary first molar for three days. A swab was performed on the third day after final exposure before the samples were observed under a light microscope. Candida albicans cultivation and calculation of the resulting colonies was carried out on Sabouraud Dextrose Agar after they had been identified by means of a germ tube test. Results: The result confirmed the absence of hyphae in the control group, while in group 1 all samples contained hyphae. Moreover, group 2 featured a dense hyphae population. A chi-square test indicated a statistical significance (p<0.05) between all groups. Conclusion: Oral candidiasis in gestational diabetes is more severe than that occurring during type 1 diabetes mellitus.
Laju aliran saliva dan insidensi kandidiasis oral pada pasien lansia perokok dan bukan perokokSalivary flow rate and incidence of oral candidiasis in elderly smokers and nonsmokers Dyah Indartin Setyowati; Leni Rokhma Dewi; Sri Hernawati; Iin Eliana Triwahyuni; Safira Zahra Marari
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 32, No 3 (2020): Desember 2020
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v32i3.28849

Abstract

Pendahuluan: Merokok merupakan salah satu kebiasaan yang sering dilakukan oleh masyarakat, termasuk kelompok lanjut usia (lansia). Kebiasaan merokok dapat mempengaruhi sekresi saliva pada lansia yang secara fisiologis mengalami penurunan sekresi saliva dan penipisan epitel mukosa mulut karena proses penuaan. Perubahan sekresi saliva dan penipisan epitel mukosa mulut dapat meningkatkan resiko infeksi rongga mulut seperti kandidiasis oral. Tujuan penelitian ini adalah untuk menganalisis perbedaan sekresi saliva melalui pengukuran laju aliran saliva serta terjadinya kandidiasis oral pada pasien lansia perokok dan bukan perokok, di Rumah Sakit Gigi Mulut  Universitas Jember (RSGM UNEJ). Metode: Penelitian ini merupakan analitik observasional pada pasien lansia RSGM UNEJ di Bagian Penyakit Mulut meliputi status merokok, pengukuran laju aliran saliva unstimulated, dan insidensi kandidiasis oral berdasarkan hasil pemeriksaan mikrobiologi oral swab. Populasi dalam penelitian ini adalah seluruh pasien lansia RSGM UNEJ Bagian Penyakit Mulut periode September 2019-Januari 2020. Metode pengambilan sampel yang digunakan adalah  total sampling. Hasil: Hasil uji Mann-Whitney menunjukkan tidak ada perbedaan signifikan antara sekresi saliva unstimulated pasien lansia perokok dan bukan perokok. Terdapat perbedaan kejadian kandidiasis oral antara pasien lansia yang merokok dengan yang tidak merokok (nilai p=0,065; derajat kepercayaan=90%). Simpulan: Tidak terdapat perbedaan laju aliran saliva pada lansia perokok dan bukan perokok, namun terdapat perbedaan terjadinya kandidiasis oral antara lansia perokok dan bukan perokok.Kata kunci: Laju aliran saliva, merokok, kandidiasis oral, lansia. ABSTRACTIntroduction: Smoking is one of the habits often carried out by the community, including the elderly. Smoking habits can affect salivary secretion in the elderly, who physiologically experience decreased salivary secretion and thinning of the oral mucosal epithelium due to the ageing process. The salivary secretion change and thinning of the oral mucosal epithelium can increase the risk of oral infections such as oral candidiasis. The purpose of this study was to analyse the differences in salivary secretion by measuring the salivary flow rate and the occurrence of oral candidiasis in elderly smokers and nonsmokers at the University of Jember Dental Hospital. Methods: This study was an observational analytic study in elderly patients of the Department of Oral Diseases University of Jember Dental Hospital, including the smoking status, measurement of unstimulated salivary flow, and the incidence of oral candidiasis based on the results of the oral microbiological swab. This study’s population were all elderly patients at the Department of Oral Diseases University of Jember Dental Hospital for September 2019-January 2020. The sampling method used was total sampling. Results: The Mann-Whitney test results showed no significant difference between the unstimulated saliva secretion of elderly smokers and nonsmokers. There was a difference in the incidence of oral candidiasis between elderly smokers’ patients and nonsmokers (p-value = 0.065; confidence level = 90%). Conclusion: There is no difference in the salivary flow rate in elderly smokers and nonsmokers, however, there are differences in the occurrence of oral candidiasis between elderly smokers and nonsmokers.Keywords: Salivary flow rate, smoking, oral candidiasis, elderly.
Hubungan Kebiasaan Merokok dengan Angka Kejadian Stomatitis Nikotina pada Nelayan Puger Jember Intan Maulia Cahya Hutami; Elyda Akhya Afida Misrohmasari; Leni Rokhma Dewi; Sri Hernawati; Kiswaluyo Kiswaluyo
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 16 No 1 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v16i1.19950

Abstract

Smoking habit is a health problem that is found globally. Indonesia has the largest number of active smokers, reaching 65 million people. Fisherman is one of the occupation in Indonesia which have the largest proportion of active smokers, almost 44,5% compared to other occupation. Smoking habit triggers pathological conditions in the oral cavity. Smoking cause an inflammation of the palatal mucosa named nicotine stomatitis. The purpose was to determine the prevalence of nicotine stomatitis in fisherman at Puger Kulon and to find out the correlation between age, type of cigarette, the intensity of smoking and the incident of nicotine stomatitis in fisherman. Data were collected by interview with 301 respondents. Purposive sampling was used in this study. The chi- square test was used to examine the correlation between age, type of cigarette and the intensity of smoking with the incident of nicotine stomatitis. The prevalence of nicotine stomatitis in fisherman at Puger Kulon Village is 5.3% and age, type of cigarette, and intensity of smoking did not have a significant correlation to the incident of nicotine stomatitis in fisherman at Puger Kulon Village Puger District Jember Regency.
MANAGEMENT OF RECURRENT APHTHOUS STOMATITIS WITH PSYCHOLOGICAL STRESS (Case Report) Ayu Mashartini Prihanti; Dyah Indartin Setyowati; Leni Rokhma Dewi
UNEJ e-Proceeding 2022: E-Prosiding Kolokium Hasil Penelitian dan Pengabdian kepada Masyarakat
Publisher : UPT Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Recurrent aphthous stomatitis (RAS) is an inflammation of the soft tissues of the mouth characterized by recurrent ulcers in the absence of other underlying diseases. Pain and discomfort in the area around the ulcer can be caused by mastication, or during speech. The characteristics of RAS are in the form of recurrent ulcers in the oral cavity with a round or oval shape and edges surrounded by erythema with a gray-yellow base of the lesion. RAS occurs starting at a young age, namely children and puberty, and can occur in adults. RAS is clinically divided into 3 types, namely major, minor, and herpetiform. A 21-year-old female patient came to the RSGM Universitas Jember with complaints of stomatitis in the mouth. Canker sores recur at least 1 year 3-5 times, and usually heal on their own in about 10 days. Intra-oral examination of the lower and lateral labial mucosa of the right tongue found ulcers, round, 2-3mm in diameter, white center, erythematous edges, clear boundaries. Based on the examination, the patient was diagnosed with Minor Recurrent Aphthous Stomatitis with a predisposition to psychological stress. The patient was given topical anti-inflammatory aloe vera therapy with multivitamin becomzet (vitamin B complex, A, C, E, and Zinc). The patient showed a positive response to the therapy.
Nutritional Status and Prevalence of Angular Cheilitis on Children in Jember Agroindustrial Environment Dyah Setyorini; Sulistiyani Sulistiyani; Risma Nur Baiti; Niken Probosari; Roedy Budi Rahardjo; Berlian Prihatiningrum; Sukanto Sukanto; Dwi Prijatmoko; Leni Rokhma Dewi
Insisiva Dental Journal: Majalah Kedokteran Gigi Insisiva Vol 11, No 2 (2022): November
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/di.v11i2.15589

Abstract

Insufficient dietary intake in school-age children can result in a weakened immune system, leading to susceptibility to illness. Children will easily be exposed to infectious diseases such as angular cheilitis. Jember has a large population of farmers, categorized as a low-paid occupation. The type of food consumed will affect each person's nutritional status. This study aims to identify the relationship between nutritional status and food intake with the prevalence of angular cheilitis in children grades I–III SDN 7 Nogosari in the agro-industrial setting of Jember. Analytical observation with a cross-sectional design was employed with 58 students as samples, whose nutritional health was assessed using the BMI/U index, visual examination angular cheilitis, and 24-hour recall method of food intake. The SPSS test was undertaken to investigate how variations in macronutrient and micronutrient consumption affect angular cheilitis in each nutritional status. Micronutrient intake that affected angular cheilitis had exceeded the RDA. Furthermore, the SPSS test showed no difference in the consumption of macronutrients and micronutrients in each nutritional status, supporting the occurrence of angular cheilitis at a rate of 0%. In the agro-industrial setting of Kebun Renteng, Jember Regency, students at SD Negeri 7 Nogosari grades I - III had a good nutritional profile with zero percent of angular cheilitis prevalence. It was impossible to determine the association between dietary status and the prevalence of angular cheilitis.
Korelasi perilaku pencarian informasi kesehatan gigi dan mulut dengan faktor sosiodemografi pada remaja: studi cross-sectional Andriono Dermawan; Surartono Dwiatmoko; Leni Rokhma Dewi
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 35, No 2 (2023): Agustus 2023
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v35i2.47155

Abstract

ABSTRAKPendahuluan: Kesehatan gigi dan mulut merupakan hal yang penting untuk dijaga karena dapat memengaruhi kesehatan seluruh tubuh. Hal yang dapat memengaruhi kesehatan gigi dan mulut ada perilaku. Perilaku pencarian informasi dan perilaku kesehatan gigi dan mulut dapat dipengaruhi oleh faktor sosiodemografi. Remaja memiliki rasa ingin tahu yang tinggi, tetapi biasanya tidak mengevaluasi sumber informasi yang mereka gunakan. Penelitian ini bertujuan menganalisis korelasi perilaku pencarian informasi kesehatan gigi dan mulut dengan faktor sosiodemografi pada remaja. Metode: Jenis penelitian observasional analitik dengan rancangan cross-sectional menggunakan instrumen kuesioner. Variabel penelitian adalah perilaku pencarian informasi kesehatan gigi dan mulut dan faktor sosiodemografi (usia, jenis kelamin, tempat tinggal, pendidikan orang tua, dan pendapatan orang tua). Populasi penelitian adalah siswa SMP tahun ajaran 2021/2022 semester gasal sebanyak 70.913. Teknik penentuan jumlah sampel menggunakan rumus Slovin. Sampel diambil menggunakan teknik random cluster random sampling. Distribusi secara proporsional menggunakan rumus oleh Bowley. Data dianalisis menggunakan uji non parametric, yaitu Spearman Rank Correlation. Hasil: Nilai signifikansi untuk variabel perilaku pencarian informasi dengan variabel usia (p=0,001), jenis kelamin (p=0,000), pendidikan orang tua (p=0,000), dan pendapatan orang tua (p=0,000), dan lokasi tempat tinggal (p=918). Korelasi termasuk sedang pada daerah perkotaan (0,410) dan lemah pada daerah pegunungan (0,410) dan dataran rendah (0,314). Nilai hasil uji Spearman Rank Correlation menunjukkan bahwa perilaku pencarian informasi kesehatan gigi dan mulut berkorelasi dengan usia, jenis kelamin, pendidikan orang tua, dan pendapatan orang tua, sedangkan dengan lokasi tempat tinggal tidak berkorelasi. Simpulan: Terdapat korelasi antara perilaku pencarian informasi kesehatan gigi dan mulut dengan faktor sosiodemografi usia, jenis kelamin, pendidikan orang tua, dan pendapatan orang tua remaja di Kabupaten Jember, sedangkan variabel tempat tinggal tidak menunjukkan korelasi yang bermaknaKata kunciperilaku, informasi, kesehatan gigi dan mulut, faktor sosiodemografi, remajaCorrelation of oral health information seeking behavior with sociodemographic factors in adolescents: cross-sectional study ABSTRACTIntroduction: Maintaining dental and oral health is crucial as it can impact the body's overall well-being. Various factors can influence dental and oral health; among them, behaviours play a significant role. These behaviours encompass seeking information about dental and oral health and sociodemographic factors that can influence them. While often curious, teenagers overlook the evaluation of information sources they employ. This study examines the correlation between adolescents' behaviour in seeking oral health information and sociodemographic factors. Methods: This study employs an analytical observational research approach with a cross-sectional design, employing a questionnaire as the research instrument. The study focuses on two main variables: dental and oral health information-seeking behaviour and sociodemographic factors, including age, gender, place of residence, parental education, and parental income. The research population comprises 70,913 junior high school students from odd semesters during the 2021/2022 academic year. The sample size was determined using the Slovin formula, and the samples were collected using a random cluster random sampling technique. To ensure representativeness, the samples were distributed proportionately according to the formula introduced by Bowley. A non-parametric statistical test, specifically the Spearman Rank Correlation, was employed for data analysis. Results: The significance values for the information-seeking behaviour variable were as follows: age (p=0.001), gender (p=0.000), parental education (p=0.000), parental income (p=0.000), and location of residence (p=0.918). The correlation was moderate in urban areas (0.410), weak in mountainous areas (0.410), and coastal areas (0.314). The Spearman Rank Correlation test results indicated that dental and oral health information-seeking behaviour was associated with age, gender, parental education, and parental income. However, no significant relationship was found between dental and oral health information-seeking behaviour and the location of residence. Conclusion: Correlation of dental and oral health information-seeking behaviour and sociodemographic factors, including age, gender, parental education, and parental income, among adolescents in Jember Regency. However, the variable of residence does not exhibit a significant correlation.Keywordsbehavior, information, dental and oral health, sociodemographic factors, adolescents