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All Journal Pharmaciana: Jurnal Kefarmasian JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Endang Darmawan
Fakultas Farmasi, Universitas Ahmad Dahlan, Yogyakarta
Chemistry Education Health Professions Medicine & Pharmacology Other

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Brief counseling by pharmacists enhances the knowledge, perceptions, and compliance of first and second-trimester pregnant women consuming ferrous fumarate at Jetis Community Health Center of Yogyakarta Nurul Kusumawardani; Endang Darmawan; Akrom Akrom; Sulistiari Retnowati
Pharmaciana Vol 9, No 2 (2019): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1048.858 KB) | DOI: 10.12928/pharmaciana.v9i2.13186

Abstract

In Indonesia, the prevalence of anemia during pregnancy increased from 37.1% in 2013 to 48.9% in 2018. It plays a significant part in elevated maternal mortality and perinatal rates. This research aimed to determine the influence of a brief counseling intervention by pharmacists based on the ‘5A’ strategy that had been modified to include the knowledge, perceptions, and compliance of pregnant women with the recommended consumption of ferrous fumarate as anemia treatment and prevention. It is a quasi-experimental study with a pretest-posttest control group design. The data were collected prospectively from December 2018 to February 2019. The sample consisted of 26 respondents, divided into a control group and an intervention group. Each group comprised 13 pregnant women in their first and second trimester (ranging from 12 to 27 weeks). The knowledge, perceptions, and compliance in each group were measured on the first day of visit (Day 1; pretest) and Day 31 (posttest) after the intervention. The results showed a significant difference in average scores between the pretest and posttest in the intervention group (p<0.001 for knowledge, perceptions, and compliance parameters) but an insignificant difference in the control group (p=0.185, p=0.366, and p=0.111, respectively). Score difference or improvement was determined from the relative risk (RR) values of the three parameters (4.55, 4.54, and 10.29, respectively, with p<0.50). As a conclusion, a brief counseling intervention based on the modified ‘5A’ strategy can enhance the knowledge, perceptions, and compliance of first and second-trimester pregnant women at Jetis Community Health Center with the proper consumption of Fe fumarate as an iron supplement.
Efek Kapsul Ekstrak Etanol Kelopak Bunga Rosella (Hibiscus sabdariffa L.) terhadap Kadar Bilirubin Sukarelawan Sehat Nur Azizah; Endang Darmawan; Laela Hayu Nurani
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 4 No. 1 (2017): Jurnal Farmasi dan Ilmu Kefarmasian Indonesia
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (248.832 KB) | DOI: 10.20473/jfiki.v4i12017.13-18

Abstract

Pendahuluan: Hibiscus sabdariffa adalah salah satu ramuan tradisional yang memiliki banyak manfaat termasuk efek imunostimulan, karena banyak mengandung antioksidan di dalamnya termasuk anthocyanin dan flavonoid. Berdasarkan aktivitasnya pada tes praklinis, H.sabdariffa telah memenuhi syarat untuk melanjutkan ke fase uji klinis. Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh kapsul ekstrak etanol kelopak bunga rosella (Hibiscus sabdariffa L.) pada kadar bilirubin  11 sukarelawan sehat  pria dan 10 sukarelawan sehat wanita. Metode: Penelitian ini menggunakan rancangan pre-post treatment. Sukarelawan sehat mengkonsumsi kapsul ekstrak etanol kelopak bunga rosella selama 30 hari dengan dosis 500 mg sekali sehari pada malam hari. Tes Bilirubin dilakukan pada hari ke-0; 31 dan 45, menggunakan metode Jendrassik dan Grof. Hasil dianalisis menggunakan SPSS dengan paired t-test dan uji Wilcoxon. Hasil: Perbandingan nilai rata-rata pada hari ke-0 dan 31, dengan hari ke-31 dan 45, dan perbandingan nilai rata-rata antara hari ke-0 dan ke-45 tidak menunjukkan perbedaan yang signifikan pada kadar bilirubin total dan direct (p > 0,05), sedangkan perbandingan nilai rata-rata untuk kadar bilirubin indirect hari ke-0 dan ke-45 menunjukkan adanya perbedaan yang signifikan (p = 0,05) akan tetapi kadar bilirubin indirect tersebut masih dalam rentang nilai normal. Kesimpulan: Kapsul ekstrak etanol kelopak bunga rosella tidak mempengaruhi kadar bilirubin total, direct dan indirect pada sukarelawan sehat.
Co-Authors Akrom, Akrom Kusumawardani, Nurul Laela Hayu Nurani Nur Azizah Sulistiari Retnowati