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The Anti-proliferative Ability of the Ethanol Extract of Annona muricata Leaves on Widr Cancer Cells Yoni Astuti; Agus Suharto; Sabtanti Harimurti; Wahyu Joko Priambodo
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 22, No 1 (2022): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v22i1.13345

Abstract

Soursop (Annona muricata) leaves are widely distributed in the tropics, including Indonesia. Soursop leaves are known to contain many anticancer compounds. Research from various countries using soursop leaves provides a different picture of the size of the dose. This research is qualitative research to determine the antiproliferative properties of soursop leaf alcohol extract on Widr cells as a model of colon cancer cells. The soursop leaves were provided from Medicinal Plant and Traditional Medicine Research and Development Center inTawangmangu. The thin-layer chromatography method was used to analyze the profile of soursop leaf extract. Microtetrazolium (MTT) proliferation test was used to analyze antiproliferative effects. The result showed that the essence quality of soursop leaves in aquoes solution was (20.65 ±0.07) % ; in ethanol solution was (19.22±0.34 ) %. The profile of ingredient soursop leaves was more visible in 366 than in 254. The ethanol extract of soursop leaves showed an antiproliferation effect at IC 50 at a dose 450 ug/ml. In conclusion, the ethanolic extract of Annona muricata showed antiproliferative properties at a dose of 450 ug/ml and having a half cell dose of IC 50.
PENERAPAN SISTEM BUDIKDAMBER (BUDI DAYA IKAN DALAM EMBER) DALAM UPAYA PEMENUHAN ASUPAN TINGGI PROTEIN UNTUK PEMENUHAN GIZI KELUARGA Yoni Astuti; Agus Suharto; Retno Wulandari
SWARNA: Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 6 (2023): SWARNA: Jurnal Pengabdian Kepada Masyarakat, Juni 2023
Publisher : LPPM Sekolah Tinggi Ilmu Ekonomi 45 Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/swarna.v2i6.553

Abstract

Pemberlakuan PSBB secara serentak di seluruh kota di Indonesia menimbulkan efek samping kurang menguntungkan terhadap perkembangan masyarakat dan ekonomi. Usia lansia memiliki kerentanan akan resiko gangguan kesehatan baik penyakit degenerative maupun infeksi. Terlebih pada kondisi saat ini dimana penyebaran covid sangat masif ini. Oleh karena itu lansia membutuhkan kualitas hidup yang baik dengan terpenuhinya asupan makanan, rekreasi, olah raga, bersosialisasi, dan lain- lain. Lansia di Patukan belum memiliki kegiatan yang bersifat rekreasi yang berdampak pada ketahanan pangan keluarga. Pengabdian ini bertujuan untuk memberikan pengetahuan kepada lansia dalam mengurangi obesitas sentral dalam mengatur pola gizi. Selain itu memberikan pelatihan BUDIKDAMBER dan kangkung untuk ketahanan pangan serta mendapat hasil berupa makanan bergizi dan protein tinggi.  Metode pelaksanaan berupa penyuluhan gizi dan pembuatan budikdamber, dan praktek budikdamber peserta yang aktif mengikuti pelatihan sebanyak 11 orang dari pengaruh pengajian dan pengurus Lansia. Kegiatan ini dilakukan selama 5 bulan. Hasil pengabdian ini adalah terdapat peningkatan pengetahuan gizi sebesar 1,11%, pelaksanaan budikdamber selama 4 bulan dengan rerata 90,1% peserta berhasil dan bisa memanfaatkan lele serta kangkung sebagai asupan makanan. Kegiatan pengabdian ini berhasil dilakukan dan mendapat sambutan antusias peserta untuk terus melakukan budikdamber sebagai alternative penyediaan asupan gizi keluarga. Program ini dapat ditularkan ke tetangga lain  untuk diikuti dengan memanfaatkan sarana ember atau apapun yang bisa di gunakan untuk ternak lele.
Screening blood glucose and blood pressure to prevent the risk of diabetes mellitus and hypertension Yoni Astuti; Agus Suharto; Rifki Hulalata
Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Vol. 6 No. 3 (2022)
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jpm.v6i3.6689

Abstract

During the covid 19 pandemic, Gamping Lor did not hold activities that risk causing crowds in order to avoid the transmission of covid 19, thus they didn’t do any activity. This condition will worsen public health conditions, which are vulnerable to exposure to NCD (Non-Communicable Diseases). In Indonesia, the number of people with DM (Diabetes mellitus) is estimated to increase by 2 times in 2030. The purpose of this service is to conduct screening for early detection of diabetes and hypertension in vulnerable communities of Gamping Lor. The method used is counseling and examination practice. The results of the activity there were 68 participants consisting of women 89.7% men 11.3%. with a picture of the following conditions; Hypertension, 35.3% prehypertension 27.3%, Normal 29.4%, Low 7.3%; hyperglycemia 15.2%, hypoglycemia, 4.5%, normal 83.3%; BMI status; Thin 11.11%, ideal,22.22%, Overweight, 20.6% Obesity level 1 , 34.9%; obesity grade 2; 11.11%. Participants with high hypertension conditions, but more normal sugar levels. Participants overweight to obesity are higher than the ideal and thin. Conclusion : Service I I went well according to plan. More participants were affected by pre and hypertension, but normoglucose, on the other hand, experienced the most overweight and obesity. So it is important to do a diet and fat burning program according to age.