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All Journal Dentika Dental Journal Majalah Kedokteran Gigi Indonesia Journal Of Syiah Kuala Dentistry Society Jurnal Kesehatan Gigi Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Padjadjaran Journal of Dental Researchers and Students Jurnal Material Kedokteran Gigi MDJ (Makassar Dental Journal)

Winny Yohana, Winny

Bagian Oral Biologi Fakultas Kedokteran Gigi Universitas Padjadjaran

Author-ID : 3064867

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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MANAGEMENT OF TONSILLOLITH PALATINE: PENATALAKSANAAN BATU TONSILA PALATINA Yohana, Winny
Dentika: Dental Journal Vol. 21 No. 01 (2018): Dentika Dental Journal
Publisher : TALENTA

Tonsillolith Palatine are stones that logded in tonsillar palatine crypt, tonsillolith are stones that caused by an accumulation of sulfur-producing bacteria, fungus, desquamated cells, food debris, and mucus that collect in the tonsillar crypts. Tonsillolith also known as tonsil stones, tonsillar concretion, or lith. Tonsilloliths have been recorded weighing from 0,3g to 4g. It may be difficult to remove, but are usually not harmful. Tonsillolith can be unilateral or bilateral. Occurs in young adult and are rare in children. Etiologi is unknown, it has been shown that the calcification develop with mass of desquamated epithelium cells, serum, food debris and bacterial colony. This case reports a patient with tonsillolith palatine. A -55 years-old female came to a private clinic, she complained difficult to swallow, sore throat, itching in right tonsillar, a foreign body-like sensation. On clinical examination, a superficial tonsillolith may be seen as white hard mass within the right tonsillar, tonsillar slightly inflammation. The tonsillolith size is 2x3x1mm. Treatment is usually removal of the tonsilliths by excavator and although mouthwash, clindamycin 300mg three times a day, diclofenac sodium 50mg three times a day, gargling helps wound healing. After tonsillith excavated , a week later the wound healing is well. Her right tonsil palatine looks healthy, wound healing is normal no sore throat, prognosis is good. Healing will be perfect when eating soft food. Successful treatment depends on good cooperation between the patient and the doctor. Keywords: tonsillolith palatine, sore throat, excavated

Peningkatan Ketebalan Epitel Mukosa Bukal setelah Aplikasi Ekstrak Daun Sirih Winny Yohana; Ame Suciati; Myrna Rachmawati
Majalah Kedokteran Gigi Indonesia Vol 1, No 1 (2015): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Daun sirih termasuk tanaman herbal yang digunakan untuk bahan alternatif pengobatan, karena kandungannya yang berkhasiat sebagai antimikroba, antiplak, antioksidan, dan mudah didapat serta ekonomis. Penelitian bertujuan untuk mengetahui ketebalan epitel mukosa mulut tikus Wistar setelah aplikasi ekstrak daun sirih. Penelitian bersifateksperimental pada tiga kelompok yang masing-masing terdiri 9 ekor tikus Wistar. Kelompok pertama sebagai kontrol, kelompok kedua dan ketiga diberikan aplikasi ekstrak daun sirih 15 hari dan 35 hari. Tikus dikorbankan sesuai waktu yang ditentukan lalu dibuat sedian histologis dan pewarnaan HE untuk pengamatan ketebalan epitel. Data ukuranepitel diuji menggunakan uji parametric uji T independen. Hasil penelitian menunjukkan peningkatan ketebalan epitel yang bermakna dicapai oleh kelompok ketiga (±15,61 μm, p=0,002), sedangkan pada kelompok pertama dan kedua tidak terdapat peningkatan ketebalan epitel (p=0,261). Aplikasi ekstrak daun sirih dapat meningkatkan ketebalan epitel mukosa bukal tikus wistar. Increase in Buccal Mucous Epithelium Thickness after Application of Betel Leaf Extract. Betel leaf (Piper Betle Linn) is a herbal ingredient. It is widely used because of its antibacterial power, anti-inflamatory and antioxidant properties. It is readily available in affordable price. The aim of this study is to determine of buccal mucous epithelium thickness of Wistar rats after the application of betel leaf extract. This was an experimental laboratory research which was performed in three groups of Wistar rats. The first group was the control group. The second and third group were those given betel leaf extract for 15 and 35 days. Each group contained nine rats. The rats were sacrificed at the time determined and made histological slide with HE staining for observation of epithelial thickness. The data of the size of epithelium were tested using independent parametric T test. The result shows a significant increase in buccal mucous epithelium thickness on the third group (15,61μm, p=0,002). Conversely, there is no increase in buccal mucous epithelium thickness on another group (p=0,261). In conclusion, the increase in buccal mucous epithelium thickness of Wistar rats occurred after the application of betel leaf extract.

PERBANDINGAN CAIRAN FIKSASI BOUIN DENGAN BUFFER FORMALIN TERHADAP HEPAR TIKUS PUTIH Winny Yohana
Journal of Syiah Kuala Dentistry Society Vol 2, No 2 (2017): JULY
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.706 KB)

Histopathological examination plays an important role in assisting the diagnosis of disease. One indispensable ingredient is a liquid fixation. fixation is a critical step in the preparation of histological section by which body tissue immersed in fixation liquid and preserved from decay thereby preventing autolysis and putrefaction. The aim of this study is to determine the better fixation in between bouin liquid and buffer formalin. The study was an experimental laboratory of two rats. A rat is injected fluids Bouin, others injected buffer formalin. The rat’s liver is taken and immersed into a fluid according to the injection of a liquid fixation. The rat’s liver was histologically prepared with hematoxylin eosin staining. The assessment by microscopically examination at 450X magnification. As an indicator seen from the changes in the nucleus of the cell, if there is a cell necrosis (bad) and normal cells (good). The study result shows that Bouin liquid got more normal cells (84.61%), while buffer formalin (38.46%). In conclusion, bouin liquid better than buffer formalin Keywords: fixation, liquid bouin, buffer formalin

Neutrophil-to-Lymphocyte Ratio (NLR) as An Inflammation Degree Marker in Tongue Cancer Patient Syakira Husna Lathifah; Winny Yohana; Moch. Rodian
Jurnal Kesehatan Gigi Vol 8, No 2 (2021): Desember 2021
Publisher : Jurusan Keperawatan Gigi, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkg.v8i2.7024

Tongue cancer is one of the most common malignancies of all oral malignancies. Cancer staging is induced by a systemic inflammatory response with one of the markers, one of them is neutrophil-lymphocyte ratio (NLR). This study aims to provide an overview of the NLR as a marker of the degree of inflammation in patients with tongue cancer. This systematic literature review was conducted online from January 2021 to March 2021 against articles reporting RNL as a marker of inflammatory action in patients with tongue cancer. The search for articles referred to Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) and conducted through PubMed, PMC, ScienceDirect, and EBSCOhost with the publication year 2015-2020. Selected articles met the criteria according to the PICO framework (Population, Intervention, Comparison, Outcome). Article screening is done by reading the title and abstract, checking for duplication, and reading the entire text. Sixteen in 841 research articles with observational study design were identified, the NLR cut-off value ranges from 2.04-2.95. Nine in ten research articles suggested a relationship between the NLR value and several clinicopathological characteristics of the patient. Twelve articles mentioned that there was the association of RNL with patient overall survival (OS), disease-free survival (DFS), and disease-specific survival (DSS). The NLR value can be an indicator of the degree of inflammation in patients with tongue cancer as assessed from the parameters of the clinicopathological assessment and can be a predictive factor for patient's prognosis or survival status.

Characteristics of Age and Oral Hygiene Status on Palatine Tonsil Size in Chronic Tonsillitis Patients Tias Ayu Karina; Winny Yohana; Moch. Rodian
Jurnal Kesehatan Gigi Vol 8, No 2 (2021): Desember 2021
Publisher : Jurusan Keperawatan Gigi, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkg.v8i2.7023

Introduction: Tonsillitis is an inflammation of the palatine tonsils that caused by the invasion of microorganisms into the mucous membranes of the tonsils. Age is related to the tonsils immunological activity on the size of the palatine tonsils. Oral hygiene is one of determinant risk factor for chronic tonsillitis. This study aims to provide a characteristics of age and oral hygiene in determining the size of the palatine tonsils in chronic tonsillitis patients. Methods: This systematic literature review was conducted online from January to March 2021 against articles reporting on age, palatine tonsils size, and oral hygiene on chronic tonsillitis. The search for articles referred to Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) which conducted through PubMed, PMC, Science Direct, and Google Scholar with the with the publication year 2015-2020. Selected articles met the criteria according to the PICO framework (Population, Intervention, Comparison, Outcome). The articles were screened by checking for duplication, reading the titles and abstracts, and the full text articles. Results: Twelve in 16 research articles (75%) mentioned that there was a relation between age and enlargement of the size of the palatine tonsils in chronic tonsillitis patients, and one in 16 articles (6,25%) mentioned that there was no relation between age and tonsillar hypertrophy. Three articles (18,75%) mentioned the role and relationship of bacteria in the oral cavity related to the process of the occurrence of chronic tonsillitis. Two in 3 research articles (67%) mentioned that there was a relation between the oral hygiene status and enlargement of the size of the palatine tonsils in chronic tonsillitis patients. One in 3 articles (33%) mentioned that there was no relation. Conclusion: Ages 5-15 years had T3 tonsil size (70%), ages 13-15 years had T2 tonsil size (80%), ages 16-48 years had T2 tonsil size (76.30%) and ages 19-25 years had T3 tonsil size (53%). This means that all ages could be experience of tonsil enlargement in chronic tonsillitis. Adults had bad oral hygiene status (76.30%), meanwhile in children only 14.47% in chronic tonsillitis patients.

Analysis of Ki-67 expression as clinicopathological parameters in predicting the prognosis of adenoid cystic carcinoma Silvi Kintawati; Murnisari Darjan; Winny Yohana
Dental Journal (Majalah Kedokteran Gigi) Vol. 50 No. 4 (2017): December 2017
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Adenoid cystic carcinoma is a malignant salivary gland tumor located in the head and neck region. Although complete surgical resection and complementary radiotherapy have been shown to improve long-term survival rates, the prognosis of adenoid cystic carcinoma remains poor. Ki-67 expression is considered a marker for the cellular proliferation rate, the detection of its expression usually being related to the aggressiveness and unfavorable prognosis of adenoid cystic carcinoma in the salivary gland. Purpose: This study was conducted to quantify the expression of Ki-67 in adenoid cystic carcinoma and to correlate the result with clinical parameters and histopathological grading in determining the prognosis. Methods: Twenty three cases of salivary gland adenoid cystic carcinoma were identified at the Department of Anatomical Pathology, Dr. Hasan Sadikin Hospital between 2013 and 2015. Clinical data such as age, gender, location of tumor and histopathological grading was also collected. The expression of Ki-67 was assessed by immunohistochemical means to determine the correlation of Ki-67 with clinical parameters and histopathological grading. Results: There were no significant differences between the expression of Ki-67 and clinical parameters, although a very strong correlation existed between the expression of Ki-67 and histopathological grading (p < 0.01). Conclusion: There were no correlation between the expression of Ki-67 and clinical parameters, although a correlation existed between the expression of Ki-67 and histopatological grading in salivary gland adenoid cystic carcinoma. Thus, clinical parameters were unusable in determining the prognosis of adenoid cystic carcinoma, although Ki-67 expression could be used for this purpose.

Variasi normal lidah manusia pada subras Deutro MelayuNormal variation of human tongue on Deutro Malay subrace Denta Asnatasia Nurmadhini; Winny Yohana; Marry Siti Mariam
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 31, No 1 (2019): April 2019
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Pendahuluan: Lidah merupakan organ yang terdiri dari otot rangka dan dilapisi oleh membran mukosa. Organ ini merupakan salah satu indikator yang baik untuk diagnosis secara klinis dan karakteristiknya dapat dipengaruhi oleh ras. Tujuan penelitian adalah untuk mengetahui gambaran variasi normal lidah manusia pada subras Deutro Melayu sebagai suatu karakteristik lidah. Metode: Penelitian deskriptif dilakukan pada 96 mahasiswa Fakultas Kedokteran Gigi Universitas Padjadjaran angkatan 2014 yang terdiri dari 87 wanita dan 9 laki-laki. Sampel diambil dengan teknik purposive sampling. Penelitian dilakukan dengan mengamati lidah secara visual dalam keadaan protrusif dan tidak tegang. Lidah diamati berdasarkan bentuk dan tekstur permukaan kemudian difoto untuk dokumentasi. Analisis data dilakukan dengan distribusi frekuensi relatif. Hasil: Persentase bentuk lidah yang paling banyak ditemukan adalah persegi, membulat, persegi panjang, dan segitiga tajam, masing-masing sebanyak 46,87%; 44,79%; 5,20%; 3,12%; dan tidak ditemukan bentuk segitiga tumpul. Tekstur permukaan yang paling banyak muncul adalah tanpa fisura, diikuti oleh fisura vertikal sentral, vertikal lateral, sentral, dan horizontal sebanyak masing-masing 54,17%; 18,75%; 14,58%; 8,33%; dan 4,17%. Simpulan: Variasi normal bentuk lidah manusia yang paling sering ditemukan pada subras deutromelayu adalah persegi, sedangkan tekstur permukaan lidah paling banyak tanpa fisura.Kata kunci: Variasi normal, lidah, subras Deutro Melayu ABSTRACTIntroduction: Tongue is an organ consisted of skeletal muscle and covered by mucous membranes. This organ is a good indicator of clinical diagnosis, and its characteristics can be influenced by race. This study was aimed to describe the normal variation of the human tongue on Deutro Malay subrace as the tongue characteristics. Methods: A descriptive study was conducted on 96 students of Faculty of Dentistry Universitas Padjadjaran batch 2014, consisted of 87 women and 9 men. Samples were taken by purposive sampling technique. The research was carried out by observing the tongue visually in a protrusive and relax state. The tongue was observed based on the shape and surface texture then photographed for documentation. Data analysis was performed by relative frequency distribution. Results: The most found tongue shape was square, followed by rounded, rectangular, and sharp triangles, which were 46.87%; 44.79%; 5.20%; and 3.12% respectively, with no blunt triangle was found. The surface texture most appeared was without fissure, followed by a central vertical, vertical, central, and horizontal fissure, which were 54.17%; 18.75%; 14.58%; 8.33%; and 4.17% consecutively. Conclusion: The normal variation in the tongue shape of Deutro Malay subrace mostly found is square and the most surface texture is without fissure.Keywords: Normal variation, tongue, Deutro Malay subrace

Enamel print pattern in Deutero-Malay sub race based on extracted female permanent maxillary central incisors Tan Kien Huat; Murnisari Dardjan; Winny Yohana
Padjadjaran Journal of Dentistry Vol 32, No 1 (2020): March 2020
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol32no1.23959

Introduction: Enamel print pattern is a series of lines representing the enamel rod ends pattern. These lines are seen running in varying directions creating distinct sub-patterns; thus, enamel print pattern allows for personal identification. This study was aimed to investigate the enamel print pattern in Deutero-Malay sub race based on extracted female permanent maxillary central incisors. Methods: This study used descriptive-analytic methods. The population of this study was Deutero-Malay sub-race female individuals who came to Batu Pahat Dental Surgery, Johor, Malaysia. The samples were 31 post-extracted permanent maxillary central incisors teeth in good condition, with closed root apex. Photomicrographs and a digital photo of samples were taken, then analysed using SourceAFIS-1.7.0 biometric software. Results: The results showed that there was a combination of few sub-patterns. The most prominent sub-pattern was linear-branched (21.36%), in decreasing orders of prominence were the wavy-branched (19.42%), wavy-unbranched (16.50%) and linear-unbranched (15.53%). The less common sub-patterns were the whorl-open (9.71%), loop (6.80%), whorl-closed (5.83%) and stem-like (4.85%). Conclusion: The enamel print pattern in every central incisor has no similarity; hence can be a possible tool for personal identification.

Evaluation of severity level, stress, and bad habit among dental students with exfoliative cheilitis Sangary Sri Sivabalasundram; Erna Herawati; Winny Yohana
Padjadjaran Journal of Dentistry Vol 34, No 1 (2022): March
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol34no1.28781

Introduction: Exfoliative cheilitis (EC) is one of the most common cheilitis found in the community. This lesion can cause difficulty in mouth opening, speech difficulties, and reduced aesthetical value of the lips. EC is a chronic inflammation characterised by desquamation, erythema, and crusting on the upper or lower lip. This study evaluated severity level, stress, and bad habit among dental students with exfoliative cheilitis. Methods: The method used in this research was descriptive with a total sampling method on the populations of dental students batch of 2016 to 2018 of the Faculty of Dentistry Universitas Padjadjaran, which obtained 83 dental students with EC. The lips were then examined, and data was recorded. EC was classified into three stages in clinical manifestation: mild, moderate, and severe exfoliative cheilitis. The data were presented with a simple frequency distribution table. Result: 30.1% of the research subjects had mild EC, 53% had moderate EC, and 16.9% had severe EC. The predisposing factors of EC in this research were stress and bad habits, where the percentage contribution were 53% and 16.9%, respectively. Students were also found with both stress and bad habits with a percentage contribution of 30.1%. Conclusions: Moderate exfoliative cheilitis is most commonly found with desquamation and erythema clinical features. The predisposing factor of exfoliative cheilitis is stress which has the highest percentage among dental students.

Salivary pH before and after cranberry juice consumption Dwiana Lisany Marunduri; Rosiliwati Wihardja; Winny Yohana
Padjadjaran Journal of Dentistry Vol 32, No 3 (2020): November 2020
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol32no3.16803

Introduction: Cranberry (Vaccinium macrocarpon) is commonly consumed as a source of antioxidants. The cranberry juice has a sour and a little bit of bitter taste that can affect the salivary pH. The sour taste is a result of its high content of proanthocyanidin. Cranberry juice plays a role in maintaining oral and dental health. Cranberries’ flavonol and proanthocyanidin content play a role in preventing dental caries by preventing the growth of Streptococcus mutans. This study was aimed to compare the salivary pH before and after cranberry juice consumption. Methods: This research was quasi-experimental. The research population was the students from the Faculty of Dentistry Universitas Padjadjaran, and the sampling method was purposive sampling. Thirty-five male and female students with no history of systemic disease and drug administration, no orthodontics appliance and denture, were involved in this experiment. Students with lesions on oral mucosa were also excluded from this study. The pH measurement was performed with a digital pH meter to record the salivary pH ratio before and after consumption of cranberry juice. Before salivary pH comparison analysis was performed, the normality test was conducted, then the analysis was continued using the paired t-test. Statistical analysis was determined at α=0.05. Results: The average values of salivary pH ratio before and after consumption of cranberry juice were 6.714 and 7.246, respectively. The normality test showed that the p-value before and after consumption of cranberry juice were 0.143 and 0.285, respectively (p-value>0.05), which categorised in the normal distribution. The paired t-test statistical analysis showed the p-value of 0.001 (p-value<0.05), which considered as significant. This result indicated that there was a significant difference in the salivary pH before and after consumption of cranberry juice. Conclusion: The salivary pH is increasing after cranberry juice consumption.

Co-Authors Alisha Zuchraini Pandji Ame Suciati Denta Asnatasia Nurmadhini Dwiana Lisany Marunduri Erna Herawati Kartika Indah Sari Marry Siti Mariam Moch. Rodian Moch. Rodian Murnisari Dardjan Murnisari Darjan Myrna Rachmawati Nabila Dara Lathifah Rosiliwati Wihardja Sangary Sri Sivabalasundram Silvi Kintawati Syakira Husna Lathifah Tan Kien Huat Tias Ayu Karina Willyanti Soewondo, Yurika Ambar Lita

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