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All Journal Jurnal Kedokteran Diponegoro GIZI INDONESIA Amerta Nutrition
Deny Yudi Fitranti
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Journal : GIZI INDONESIA

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PENGARUH PEMBERIAN YOGHURT DAN SOYGHURT SINBIOTIK KAYU MANIS (Cinnamomum burmanii) TERHADAP KADAR TRIGLISERIDA DAN TOTAL KOLESTEROL PADA TIKUS PRA-SINDROM METABOLIK Galuh Dwi Astuti; Deny Yudi Fitranti; Gemala Yudi Anjani; Diana Nur Afifah; Ninik Rustanti
GIZI INDONESIA Vol 43, No 2 (2020): September 2020
Publisher : PERSATUAN AHLI GIZI INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36457/gizindo.v43i2.448

Abstract

Dyslipidemia is one of the metabolic syndrome risk factors characterized by elevated triglyceride serum and total cholesterol. The yoghurt and soyghurt cinnamon contain lactic acid bacteria, fiber, and bioactive components which play a role to improve triglyceride serum and total cholesterol. The study aimed was to determine the effect of yoghurt and soyghurt symbiotic cinnamon on triglyceride serum and total cholesterol in pre-metabolic syndrome rats. This research was experimental with pre and post control group design. 15 male Sprague Dawley rats that were divided into 5 healthy rats as a negative control group (K) and 10 pre metabolic syndrome rats which were induced with high fat and fructose diet for P1 (yogurt) and P2 (soygurt) which 5 rats per group. The intervention was given for 28 days with a dosage of 0,017ml/BW. P2 (25,50 %) showed reduction of triglyceride higher than P1 (11,34%) and K (12,37%). The total cholesterol reduction in P1 (5,65%) and P2 (7,10%) was lower than K (7,80%). There is no effect of yoghurt and soyghurt synbiotic cinnamon on triglyceride and total cholesterol in pre-metabolic syndrome rats. The other study which has a higher dosage and longer duration in subject with 2 criteria of pre syndrome metabolic is needed. ABSTRAKDislipidemia merupakan faktor risiko sindrom metabolik ditandai kadar trigliserida dan kolesterol total diatas batas normal. Yoghurt dan soyghurt sinbiotik kayu manis mengandung bakteri asam laktat, serat, serta komponen bioaktif yang dapat memperbaiki kadar trigliserida dan kolesterol total pada pra sindrom metabolik. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian yoghurt dan soyghurt sinbiotik kayu manis terhadap kadar trigliserida dan kolesterol total tikus pra sindrom metabolik. Penelitian ini merupakan true experimental dengan rancangan pre-post test control group. Subjek merupakan 15 tikus Sprague Dawley jantan yang dibagi menjadi 5 tikus normal sebagai kontrol (K) dan 10 tikus pra sindrom metabolik dengan diet tinggi lemak dan fruktosa untuk kelompok P1 (yoghurt) dan P2 (soyghurt) masing-masing 5 tikus. Intervensi yoghurt dan soyghurt diberikan sebanyak 0,017ml/gBB selama 28 hari. Uji beda sebelum dan setelah perlakuan menggunakan Paired t-test atau Wilcoxon. Uji perbedaan antar kelompok menggunakan uji One-Way ANOVA atau Kruskal Wallis. Tidak terdapat penurunan kolesterol total dan trigliserida secara signifikan pada masing-masing kelompok (p0.05). Penurunan kadar trigliserida pada P2 (25,50%) lebih tinggi daripada K (12,37%) dan P1 (11,34%). Penurunan kadar kolesterol total pada P1 (5,65%) dan P2 (7,10%) lebih rendah daripada K (7,80%). Tidak terdapat pengaruh pemberian yoghurt maupun soyghurt sinbiotik kayu manis terhadap penurunan serum trigliserida dan kolesterol total. Diperlukan penelitian pada kondisi pra sindrom metabolik dengan dua kriteria yang sama, dengan dosis yang lebih tinggi atau durasi yang lebih lama.
POTENSI FEMALE ATHLETE TRIAD PADA ATLET REMAJA PUTRI DEFISIENSI BESI Fillah Fithra Dieny; Deny Yudi Fitranti; Firdananda Fikri Jauharany; A Fahmy Arif Tsani
GIZI INDONESIA Vol 44, No 1 (2021): Maret 2021
Publisher : PERSATUAN AHLI GIZI INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36457/gizindo.v44i1.511

Abstract

The female athlete triad (FAT) is a syndrome that occurs in female athletes who have a combination of 3 related conditions and are associated with sports. The aimed of this study to analyze the relationship between iron deficiency and the state of the female athlete triad (FAT) in female athletes. The design of this study was cross sectional with 80 subjects of female athletes aged 12-18 years from various sports, who were taken by simple random sampling. The research was conducted at the Central Java Student Center for Education and Sports Training (BPPLOP). Bivariate analysis was performed using the Spearman test. Based on Ferritin, as many as 15 subjects (18.25%) had iron deficiency anemia, and FAT syndrome was not found in the subjects, however, when each sign was seen, 20 percent were classified as polimenorrhea and oligomenorrhea, and 37.5 percent experienced eating disorders. There were a significant relationship between iron deficiency based on serum ferritin (p = 0.015; r = 0.273) and Hb levels (p = 0.002; r = 0.337) with the component of athlete's bone density. However, iron deficiency (based on serum Ferritin and Hb levels) did not show a significant association with menstrual cycle disorders and eating disorders (p 0.05). Female Athlete Triad has not been found among subjects, but athletes have experienced eating behavior disorders, menstrual cycle disorders and the risk of low bone density. Iron deficiency is associated with decreased bone density in young female athletes. ABSTRAK Female athlete triad (FAT) merupakan suatu syndrom yang terjadi pada atlet wanita yang memiliki kombinasi dari 3 kondisi yang saling berkaitan, dan berhubungan dengan olahraga. Tujuan penelitian untuk menganalisis hubungan defisiensi besi dengan keadaan female athelete triad (FAT) pada atlet remaja putri. Desain penelitian ini adalah cross-sectional dengan 80 subjek atlet putri berusia 12-18 tahun dari berbagai cabang olahraga yang diambil secara simple random sampling. Penelitian dilakukan di Balai Pemusatan Pendidikan dan Latihan Olahraga Pelajar (BPPLOP) Jateng. Analisis univariat untuk mendeskripsikan data berupa distribusi dan persentase. Analisis bivariat dilakukan menggunakan uji Spearman. Berdasarkan data serum ferritin, sebanyak 15 subjek (18,25%) mengalami anemia defisiensi besi, namun belum ditemukan kejadian FAT pada subjek, tetapi bila dilihat masing masing tanda sebanyak 20 persen tergolong polimenorea dan oligomenorea, serta 37,5 persen mengalami gangguan perilaku makan. Ada hubungan yang signifikan antara defisiensi besi berdasarkan serum ferritin (p=0,015; r=0,273) dan kadar Hb (p=0,002; r=0,337) dengan komponen kepadatan tulang atlet. Namun defisiensi besi (bedasarkan serum Ferritin dan Kadar Hb) tidak menunjukkan hubungan yang signifikan dengan gangguan siklus menstruasi dan gangguan perilaku makan (p0,05). FAT belum ditemukan pada atlet remaja putri, namun atlet sudah ada yang mengalami gangguan perilaku makan, gangguan siklus menstruasi dan risiko kepadatan tulang rendah. Defisiensi besi berhubungan dengan menurunnya kepadatan tulang atlet remaja putri.Kata kunci: atlet; remaja putri; defisiensi besi; female athlete triad (FAT) 
Co-Authors A Fahmy Arif Tsani Anjani, Gemala Diana Nur Afifah, Diana Nur Dwi Nina Wijayanti Etisa Adi Murbawani Fillah Fithra Dieny Fillah Fithra Dieny Galuh Dwi Astuti Hermina Sukmaningtyas Jauharany, Firdananda Fikri MARTHA ARDIARIA Ninik Rustanti Nurmasari Widyastuti Sekar Ratry Nurramadhani Zsa-Zsa Ayu Laksmi