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All Journal Dentino: Jurnal Kedokteran Gigi MDJ (Makassar Dental Journal) Jurnal Ilmu Bedah Indonesia
Kiki Akhmad Rizki
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Immunology & microbiology Medicine & Pharmacology

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MULTIDISCIPLINARY APPROACH IN THE TREATMENT OF SQUAMOUS CELL CARCINOMA AT REGIO GLOSSUS Tri Nurrahman; Seto Adiantoro; Kiki Akhmad Rizki; Farah Asnely
Dentino : Jurnal Kedokteran Gigi Vol 5, No 2 (2020)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v5i2.8976

Abstract

ABSTRACTBackground: Squamous Cell Carcinoma (SCC) is the most common case of oral cancer which often occurs laterally on the tongue and rarely develops on the dorsal surface of the tongue. More than half of the cases are diagnosed late, thereby reducing the survival rate of the patients. Objective: This report was intended as an evaluation for the management of squamous cell carcinoma under multidisciplinary approach between oral surgery and other departments, as well as the provision of further post-operative treatment. Case Report: The author presents a case of 68-years-old female patient with a lump and an ulcer on her tongue. Around six months prior to the visit, patient complained of tongue ulcer followed by the emergence of a lump in a size of a corn seed. The lump was gradually enlarged with constant widening of the ulcer. Pain on the tongue was also perceived. The patient was then referred to Hasan Sadikin Hospital for further treatment. Case Management: Patients underwent hemiglossectomy and Selective Neck Dissection (SND) surgical procedures performed by Oral and Maxillofacial Surgeon in collaboration with Surgical Oncologist. Furthermore, after surgery, the patient was consulted to the Hemato-Oncology Division of Internal Medicine Department for chemotherapy treatment. Conclusions: The exact diagnosis was made based on the histopathological biopsy results of the tongue tissue. Management of tongue cancer must be done multidisciplinary. Some things that must be considered in handling such cases are the eradication of the tumor, the return of oral cavity function, and the aesthetic/functional aspects of the patient. Keywords: Oral cancer, Squamous cell carcinoma, Tongue cancer
COMPLICATIONS OF RECONSTRUCTION PLATE INSTALLATION IN MANDIBULAR Leni Ruslaini; Asri Arumsari; Abel Tasman; Kiki Akhmad Rizki
Dentino : Jurnal Kedokteran Gigi Vol 6, No 2 (2021)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v6i2.12011

Abstract

Background: Mandibular resection will cause mandibular stability disturbance due to loss of some part of the bone. Instability of the mandible can cause aesthetic, physiological, and psychological malfunction. Installment of mandibular reconstruction plat on the remaining mandibular using screws were suggested to restore its stability. However, it is not uncommon that plat exposure occurs following mandibular reconstruction, caused by inaccurate adaptation of the plats to the mandibular bone. The aims of this report are to describe the various complications and managements after jaw resection and reconstruction with plates. Case Report: A 44 years old male patient complained the small defect in the chin, painless, and no fluid emited, accompanied by dermatitis. Intra oral examination showed no abnormalities. About 1 year ago the patient performed segmental resection of the mandible on the indication of ameloblastoma. The radiological x-ray showed all screw detached from the plat and radiolucent images appeared around the plat that attached to the mandible. The diagnosis was fistula at regio mentale, post resection and reconstruction surgery, suspected caused by titanium plate allergies. The provided therapies were fistulectomy, screw removal, and plate reconstruction. Post therapy conditions showed improvement and no patients complaints of pain. Conclusion: Plate exposure is a complication that can occur after the installation of the reconstruction plate, but besides that it can also cause an allergic reaction from the material used. Keywords: Complication, Mandibular Resection, Plate Reconstruction, Titanium Plate Allergies
Perubahan Volume Tumor, Jumlah Trombosit dan Kadar D–dimmer pada Karsinoma Payudara Lanjut Lokal Setelah Kemoterapi Neoadjuvan Fredy Rustomi Damanik; Maman Abdurahman; Kiki Akhmad Rizki
Jurnal llmu Bedah Indonesia Vol. 43 No. 1 (2014): September 2014
Publisher : Ikatan Ahli Bedah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46800/jibi-ikabi.v43i1.70

Abstract

Background. Locally advanced breast cancer places approximately 40–60% from all the new cases of breast cancer in developing countries. And this kind of breast cancer requires a combined therapy, i.e. chemotherapy, surgery and radiotherapy. Nowadays, the response of chemotherapy is evaluated from the reduction in tumor volume. There is also another parameter. Since half of patients with breast cancer show abnormalities of routine blood clotting factors, D–dimmer which is a fibrin degeneration product from vascular endothelial growth factor (VEGF) is used. There is an increase of plasma D–dimmer level among 86% of breast cancer patients. There is a strong relationship amongst serum VEGF and platelets count in breast cancer patient. Method. To analyze the correlation, we did an evaluation of the tumor volume, platelets count, and plasma D– dimmer among patients with locally advanced breast cancer, before and after cyclophospamide, doxorubicin, 5–fluorouracil (FAC) combined neoadjuvant chemotherapy. This was a prospective study enrolling 36 subjects. The data is obtained from the history, physical examination, laboratory and or radiological exams as it found in medical record. To have a normal distribution of the subjects, a Shapiro–Wilk test was done. Pearson correlation test was applied in evaluation of the relationship of tumor volume, platelet count and plasma D–dimmer level after chemotherapy. Data was analyzed using the SPSS program ver.19. Results. Tumor volume decreases till 153.811 cm3, the platelet level decreased till 4,958.333/mm3 and the plasma D–dimmer level also decreased up to101.389 ng/ml after FAC regimen. A significant relationship was found in platelet counts and tumor volume after chemotherapy with r of 0,391 (p=0,018). The relationship amongst the change in platelet level and plasma D–dimmer level showed a plateau which is quiet high with the value of r=0,473 (p=0,024). Conclusion. There is a positive correlation of the tumor volume, the platelet level, and plasma D–dimmer level after combined FAC neoadjuvant chemotherapy
Squamous cell carcinoma of the tongue Verawaty Mohan; Andri Hardianto; Kiki Akhmad Rizki
Makassar Dental Journal Vol. 1 No. 6 (2012): Vol 1 No 6, Desember 2012
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (396.698 KB) | DOI: 10.35856/mdj.v1i6.79

Abstract

Neoplasma rongga mulut merupakan keganasan yang jarang ditemukan di negara Barat, namun cukup banyak ditemukan di Asia. Di USA, angka insidensinya berkisar antara 3-4% dari seluruh keganasan, sedangkan di India, dapat mencapai 50% dan menjadi tumor ganas yang terbanyak. Sekitar 90% keganasan rongga mulut ini sangat berhubungan dengan konsumsi tembakau dan alkohol, sedangkan di Asia, berhubungan dengan kebiasaan mengunyah tembakau dan sirih. Predileksi terbanyak yaitu pada lidah 35%, bibir 30%, dasar mulut 15%, gingiva mandibula 12,1%, mukosa bukal 9,7%, palatum dan gingiva maksila 4,7%. Di Indonesia, insiden neoplasma rongga mulut adalah 1,5-5%, terbanyak ditemukan pada usia 55-65 tahun dan dapat bervariasi antara 40-70 tahun. Berdasarkan jenis kelamin, perbandingan laki-laki dan perempuan adalah 1:1 yang sangat berbeda dengan data dari negara Barat yaitu 4:1. Dilaporkan seorang pasien dengan keluhan benjolan pada ujung lidah bagian bawah kanan, mudah berdarah, dapat digerakkan dan teraba kenyal, tanpa disertai rasa nyeri. Penurunan berat badan disangkal dan pasien tidak merasakan adanya pembesaran KGB di lehernya. Kebersihan mulut pada pasien ini sangat buruk dengan banyaknya lubang gigi. Pasien juga mengeluh gangguan berbicara, mengunyah maupun menelan. Pasien lalu menjalani operasi pengangkatan massa tumor disertai tindakan radikal diseksi leher sebagai tindakan profilaksis. Jaringan yang diangkat diperiksakan ke laboratorium dengan hasil PA yaitu well differentiated squamous cell carcinoma.
Hemimandibulektomi disertai rekonstruksi plat AO pada ameloblastoma mandibula: Case report Eka Prasetiawaty; Herman Hambali; Kiki Akhmad Rizki
Makassar Dental Journal Vol. 2 No. 1 (2013): Vol 2 No 1 Februari 2013
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (537.907 KB) | DOI: 10.35856/mdj.v2i1.109

Abstract

Amelobloastoma adalah tumor jinak odotogenik yang lambat pertumbuhannya, paling sering terjadi pada mandibula, lokal invasif tetapi relatif, tidak ada keluhan dan jika tidak diobati dapat tumbuh menjadi ukuran besar dan menyebabkan kerusakan pada rahang dan wajah. Pengobatan yang tepat dari ameloblastoma masih kontroversial, karena tingkat kekambuhan ameloblastoma sangat tinggi, sehingga dokter melakukan pengobatan radikal dengan hemimandibulektomi. Laporan ini membahas tentang pengelolaan ameloblastoma mandibula dengan hemimandibulektomi dan rekonstruksi dengan plat mini AO titanium. Seorang wanita 30 tahun mengeluh tentang benjolan di rahang bawah kirinya. Radiografi mengungkapkan massa telah melibatkan dan menghancurkan bagian koronoideus dan kondil rahang bawahnya. Biopsi insisi mengkonfirmasi ameloblastoma di rahang bawah kirinya. Pasien dirawat di rumah sakit satu hari sebelum operasi. Setelah hemimandibulektomi dilakukan, kami melakukan rekonstruksi dengan menempatkan plat AO mini untuk mendapatkan kontur rahang bawah. Setelah itu tindak lanjut operasi kondisi pasca pasien. Disimpulkan bahwa hemimandibulektomi dan rekonstruksi dengan titanium mini plate AO adalah pilihan pengobatan yang ideal dalam mengobati ameloblastoma dari mandibula.
Co-Authors Abel Tasman Andri Hardianto Asri Arumsari Eka Prasetiawaty Farah Asnely Fredy Rustomi Damanik Herman Hambali Leni Ruslaini Maman Abdurahman Seto Adiantoro Tri Nurrahman Verawaty Mohan