Susy Andriani
Balai Penelitian dan Pengembangan Lingkungan Hidup dan Kehutanan Banjarbaru

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Karakteristik Fisika Sediaan Suspensi Ekstrak Etanol Daun Gaharu (Aquilaria microcarpa Baill.) dengan Variasi Carboxymethyl Cellulose Sodium (CMC-Na) Mia Fitriana; Wawan Halwany; Khoerul Anwar; Liling Triyasmono; Beny Rahmanto; Susy Andriani; Nur Ainah
Jurnal Pharmascience Vol 7, No 1 (2020): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i1.8087

Abstract

ABSTRAK Gaharu (Aquilaria microcarpa Baill.) merupakan salah satu hasil hutan yang memiliki aktivitas antioksidan. Ekstrak etanol daun A. microcarpa terbukti memiliki aktivitas antioksidan yang tergolong sangat aktif. Ekstrak etanol daun A. microcarpa kemudian dibuat menjadi sediaan suspensi dengan variasi CMC-Na sebagai agen pengsuspensi. Penelitian ini bertujuan untuk menentukan pengaruh konsentrasi CMC-Na terhadap karakteristik fisik suspensi ekstrak etanol daun A.microcarpa. Suspensi dibuat dengan variasi CMC-Na pada F1 (0,5% CMC-Na), F2 (1% CMC-Na) dan F3 (1,5% CMC-Na). Evaluasi sediaan suspensi meliputi organoleptis, uji viskositas, uji pH, uji homogenitas serta uji berat jenis suspensi. Nilai evaluasi suspensi dianalisis secara statistik dengan software SPSS 21. Hasil evaluasi fisik menunjukkan bahwa penambahan  konsentrasi CMC-Na akan meningkatkan nilai viskositas dan berat jenis sediaan. Kesimpulan dari pengujian ini adalah variasi konsentrasi CMC-Na mempengaruhi hasil viskositas, serta berat jenis suspensi (p<0,05) dan tidak mempengaruhi hasil organoleptis, homogenitas dan pH suspensi.  Kata kunci: Gaharu, suspensi, CMC-Na  ABSTRACT Gaharu (Aquilaria microcarpa Baill.) is one of the Borneo’s forest products that has antioxidant activity. Ethanol extract of A. microcarpa folium has been shown to have antioxidant activity that is classified as very active. The ethanol extract of A. microcarpa folium was then made into a suspension preparation with variations of sodium CMC as a suspending agent. This study aimed to determine the effect of sodium CMC concentration on the physical characteristics of the ethanol extract of A.microcarpa folium. Suspension was made with variations of sodium CMC in F1 (0.5% sodium CMC), F2 (1% sodium CMC) and F3 (1.5% sodium CMC). Evaluation of suspension preparations included organoleptic, viscosity test, pH test, homogeneity test and suspension specific gravity test. The suspension evaluation data were analyzed statistically with SPSS 21 Software.  The physical evaluation results showed that the addition of sodium CMC concentration would increase the viscosity and specific gravity of the preparation. The conclusion of this test was that variations in the concentration of sodium CMC affected the results of viscosity and suspension specific gravity (p <0.05) and did not affect the organoleptic yield, homogeneity and pH of the suspension. Keywords: Gaharu, suspension, 
Phytochemical content of traditional herbal medicines in South and Central Kalimantan Fajar Lestari; Susy Andriani
Jurnal GALAM Vol 1, No 2 (2021): Jurnal GALAM, Vol.1 No.2 2021
Publisher : Jurnal GALAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20886/glm.2021.1.2.79-92

Abstract

The use of medicine derived from natural ingredients had already begun since ancestors and passed down from generation to generation. However, the properties of those various plants were not clinically been proven. This study aims to find out phytochemical content of medicinal forest plants based on information from the local communities. The study was conducted in two ecosystem types namely wetland ecosystem in peat swamp of Sungai Rasau, Sebangau National Park, Central Kalimantan and dryland ecosystem in Meratus Mountain slope, Peramasan Bawah village, South Kalimantan. Vegetation data in the field was collected by making line transect. Phytochemical analyses qualitatively was done in the Faculty of Math and Natural Science laboratory of Lambung Mangkurat University, while specimen samples were taken from some species that commonly used by the local communities for medicinal purpose as 100 gr to 150 gr of gross weight of each plants. . Then the plant specimens were tested for their secondary metabolites comprised steroids/triterpenoids, quinone, tannin, flavonoids, saponins, and alkaloids tests in the laboratory. The research results showed that medicinal plants used by local communities were still available in their natural habitat In dryland ecosystem, there were 27 plant species discovered and 22 species found in peat swamp ecosystem that potentially use as herbal medicine. Phytochemical analyses showed that most of the plant samples were proved to have secondary metabolites in the form of steroid/triterpenoids, quinone, tannin, flavonoid, saponins and alkaloids. This condition showed that those plant species have potential as herbal medicine. However, those plant species still need further tests related to certain active ingredients potentially use as biopharmacy.Keywords: biopharmacy, peat, land, metabolite