Article Per Year (5 Year)
p-Index From 2019 - 2024
0
P-Index
This Author published in this journals
All Journal Journal of Mathematical and Fundamental Sciences
Tukiran Tukiran
Kelompok Penelitian Kimia Organik Bahan Alam, Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Institut Teknologi Bandung, Jalan Ganesa 10, Bandung 40132
Astronomy Chemistry Earth & Planetary Sciences Mathematics Physics

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Artonol B and Sikloartobilosanton dari Artocarpus teysmanii MIQ Lukman Makmur; Syamsurizal Syamsurizal; Tukiran Tukiran; Yoharmus Syamsu; Sjamsul Arifin Achmad; Euis Holisotan Hakim; Didin Mujahidin; Norio Aimi; Mariko Kitajima; Hiromitsu Takayama
Journal of Mathematical and Fundamental Sciences Vol. 31 No. 2 (1999)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Dua senyawa masing-masing turunan santon lakton, yaitu artonol B (1) dan turunan furanodihidrobenzosanton, yakni Sikloartobilosanton (2), telah ditemukan pada tumbuhan Artocarpus teysmanii Miq. (Moraceae), suatu tumbuhan langka yang endemik untuk Indonesia dan dikenal dengan nama Tipulu. Struktur molekul kedua senyawa tersebut telah ditetapkan berdasarkan data fisika dan spektroskopi (MS, 1H dan 13C NMR). Artonol B (1) dan sikloartobilosanton (2) memperlihatkan toksisitas yang tinggi terhadap udang Artemia salina, dan senyawa 2 juga memperlihatkan aktivitas antimitotik yang rendah terhadap target cdc2 kinase dan cdc25 fosfatase. Artonol B and Cycloartobiloxanthone from Artocarpus teysmanii MIQTwo compounds, a xanthone lactone derivative, namely artonol B (1) and a furanodihydrobenzoxanthone derivative, namely cycloartobiloxanthone (2) had been isolated from Artocarpus teysmanii Miq. (Moraceae), locally known as Tipulu. The structures of both compounds were elucidated based on physical and spectroscopic data (MS, 1H and 13C NMR). Both artonol B (1) and cycloartobiloxanthone (2) showed strong toxicity against Artemia salina in the shrimp bioassay, and compound 2 also showed weak antimitotic activity against cdc2 kinase and cdc25 phosphatase as the targets. Bagian ke-8 dari seri Ilmu Kimia Tumbuhan Moraceae Indonesia, untuk bagian ke-6 lihat pustaka [10].
Co-Authors Didin Mujahidin Euis Holisotan Hakim Hiromitsu Takayama Lukman Makmur Mariko Kitajima Norio Aimi Sjamsul Arifin Achmad Syamsurizal Syamsurizal Yoharmus Syamsu